UNISOM Reviews (DOXYLAMINE SUCCINATE)Average Rating: 2.5 (88 Ratings)Filter ResultsCompare UNISOM with similar:
Type: Over-the-counter Drug
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Results are sorted by Age oldest to youngest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on UNISOM: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR UNISOM | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | Sleep aid (doxylamine version) | Morning drowsiness. Fewer side effects than with Benadryl (can't remember Benadryl's generic name, it is used also in a different Unisom formulation): no hunger or dry mouth which I get with Benadryl. | This is a very powerful drug and should be available in a lower dosage. I am now taking a version (Donormyl) I buy in France which is 15 mg, divisible in two for a 7.5 mg dose, and I am very happy with that dose. Unisom is available only in 25 mg. tablets so that even if one splits the pill, as I did, the dosage is still too large. I recommended this (as the only version available in the US) to two friends who both tried and rejected it as too powerful. | F | 65 | 30 days | 7/28/2006 | 2 | Insomnia | Note: I took Doxylamine Succinate Equate Brand. Grogginess and lethargy on awakening; after a few weeks using half tablet (12.5 mg) at bedtime, couldn't fall asleep. Or, if asleep, felt awake. Worked well initially but taking a few nights in a row caused real problems. | This stuff, even at 1/2 strength (12.5 mg) caused insomnia, and also caused horrible irregular/doubled and racing heartbeat. Very stupid/scattered thoughts the next day, scrambled and disorganized. Nagging feeling of very empty stomach during day. It took me about 2 weeks to figure out it was exacerbating my sleeplessness. Couldn't fall asleep; couldn't stay asleep for more than 3 hours. Dangerous drug for some people. I would recommend being cautious with this medicine. | F | 63 | 3 weeks 12.5 1X day | 1/14/2018 | 4 | Occasional sleep aid | I experience mild personality suppression the next day, but few other side effects. | I use the Unisom sleep tabs, but have learned to break them in half, and only take 1/2 tab as my dose. When I use them I take it by 9 PM and am in bed by 9:30, as I get up at 6:30 AM -- so I'm able to get a full night's rest. Taking only the 1/2 tab seems to make it much easier to control the next day side effects, yet I always get a deep sleep. I find I take 1/2 tab maybe once a month when I need to catch up on my sleep. | M | 62 | 5 years 25 mg 1X AN | 3/25/2015 | 1 | Trouble sleeping | Anxiety Dry mouth Racy heart Heavy leg feeling Irritability | Terrible feeling left work early as the anxiety and irritability was awful and extreme dry mouth. | F | 62 | 1 days 1 1X day | 6/20/2023 | 1 | Insomnia | I take this drug only occasionally and find that I am very agitated and depressed the next day. Also, get constipation. | F | 61 | 2 days 1X day | 3/30/2013 | 5 | sleep aid | First day wonderful rested and energized. | F | 59 | 3 days 50 mg 1X day | 1/30/2011 | 5 | To fall asleep sooner | A full pill made me dopey until 5 p.m. the next day. | 1/8-1/4 of a pill has worked great for 16 years. I fall asleep in 1/2 hour, only wake up once to use the restroom, fall immediately asleep again, and wake up refreshed and alert at 6 a.m. One cup of coffee does the final morning perk up. Take 250-500 mg of magnesium before bed to soften stools. | 59 | 1/8-1/4 pi 1X day | 5/5/2015 | 3 | insomnia | I got a great nights rest. Took a whole pill first night. Then last 6, i only took half. Regardless of amount, i woke up to total lethargy. Left me with a dry throat too. I was useless at work until afternoon. | I gave it a week to see if my body would get used to it. I will not take it anymore. | M | 57 | 7 days 15mg | 8/11/2015 | 5 | Insomnia | I am using Doxylamine already for a few years. I live in Australia and take it in tablet form with the brand name Restavit. However, I take only 1/2 a tablet (12.5mg) about an hour before going to bed. I then take also a Valerian capsule and 1/2 teaspoon Tryptophan. The combination seems to work exept when I have been overstimulated by having visitors or working too late on my computer etc. I have Fybromyalgia and find that the anti-histamnine is something I also need for some of my allergies. | So far I have not found problems with taking this but I may not recognise them because of the complaints I have with Fybromyalgia. | F | 56 | 7 years | 4/14/2008 | 4 | sleep | Lots of dreaming | There are two different Unisom pills. One contains Diphenhydramine and one contains Doxylamine. I take the one that contains Doxylamine, as the other one does not let me sleep through the night and can me me jittery once awakened. | F | 56 | 90 days 25mg 1X day | 8/6/2016 | 1 | trouble sleeping | Tried two nights a few days apart. The first night sleep came easy. BUT the next day I was a basket case and had a complete melt down. So out if character for me. I never even thought it might have been a reaction.I took again several nights later and spent entire next day in a dark depression. Very scary Will never take again Count sheep, pray, read anything else | F | 56 | 2 days 25 | 5/15/2015 | 4 | insomnia | sinusitis, cough, dry mouth, swollen eyes | 1/2 a tablet really did help me sleep. However, because of side-effects, I will only use as a last resort. | M | 55 | 15 mg 1X day | 3/3/2010 | 1 | Insomnia | I didn't realize until reading all of these reviews that this medication is responsible for my heart palpitations, anxiety and tight chest! I dreaded bedtime and had sleep anxiety but after 2 weeks without taking it everything went away!!! It was also making me gain weight which I could not figure out! Hate this crappy med! Don't take it!!! | This medication also was also responsible for my tight chest and squeezing sensation which hurt and felt like i was having a heart attack all the time! | F | 55 | 6 months 25 mg 1X day | 5/31/2021 | 5 | Insomnia | did not feel any side effect. | Very satisfied | M | 54 | 2 days 1/2 25mg | 4/18/2015 | 3 | Insomnia | Sometimes it worked well for me, helping me fall and stay asleep for most of the night. Other times, however, I felt exhausted, spaced out and foggy the next day, and also suffered nausea on a few occasions. I also experienced bizarre, vivid dreams on a few occasions after taking this medication. | Doxylamine succinate is supposed to be the most sedating over-the-counter medication available, so use caution when taking it. When taking this medication, make sure you avoid other sedating substances such as alcohol, benzodiazepines (e.g., Xanax, Klonopin), and prescription sleeping pills (Ambien, Restoril, etc.). Because of the potency of this medication, you may want to start out with a smaller dose—half a pill, say, which equals 12.5 MGs—to see how you react to it. | M | 54 | 25 MG 1X day | 3/27/2014 | 2 | insomnia | It still took me nearly 5 hrs to get to sleep and an hour later I was awakened with restless feelings, twitching legs and feet. And very tired the next day. | F | 54 | 1 days 1 tablet | 2/19/2015 | 1 | Insomnia | Took this for sleep! Slept well but next day had a hungover feeling! Muscle twitching foggy fuzzy weird head feeling in the ear as well! Bad dreams and weird obsessive thinking! Off balance feeling and tired face feeling on one side of my face! | It also gives you anxiety And depressed feelings! I think this is more than just an antihistamine! You get that next day nervy stressed foggy headed feeling both in the head And ears! Sounds amplified and shocks your head and ears causing anxiety or panic! | M | 54 | 1 days 25 1X day | 2/11/2021 | 1 | Trying to help sleep | I did sleep but woke up groggy and nauseated. Brain fog, lethargic unable to concentrate and feeling of depression the next day. 24 hours later and I still feel bad. | I do not recommend this medication. | F | 52 | 1 days 30 1X day | 5/28/2021 | 4 | Insomnia | Having used sleeping meds for years and after having become highly addicted to them, Unisom brought me wonderful relief from extended insomnia when I had to stop the sleeping pills. Be warned though! I now have HYPER acidosis! Have to take up to 80mg's of acid blocking P.P.I's due to a totally messed up gastric system now. This has lead to ulcers and now gout type arthritis which the Physician says all stems from having used Unisom for close on 3 years. | F | 51 | 3 years | 1/21/2008 | 4 | Insomnia | Lingering grogginess in the morning. | Even though this is an over-the-counter drug, as far as inducing the feeling of sleepiness, it is one of the most powerful I've tried and, in that respect, works better than both Ambien and Lunesta. The problem with it for me is that it can take over an hour to kick in -- but when it does you'd better be in bed or close by. It's so strong that I have to buy it in the oval tablet form and break them in half. If I took a whole one, I'd still be in a fog for over half of the next day. As it is, even with the half tablet, I'm still too groggy in the morning which is why I don't use it more. But it's a very effective sleep medicine. | M | 51 | 18 months | 10/9/2006 |