PAMELOR Reviews (NORTRIPTYLINE HYDROCHLORIDE)

Average Rating: 3.2 (191 Ratings)

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 MIGRAINE HEADACHES ANTIDEPRESSANTS

 Type: Rx Drug

  

PAMELOR  (NORTRIPTYLINE HYDROCHLORIDE):  This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters) in the brain.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10


RATING  REASONSIDE EFFECTS FOR PAMELORCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Anxiety, Depression Dry mouth, other than that none. Pamelor has worked great for me at 25mg x 4 daily, best TCA in my opinion. M 41 22 years
5/12/2007
 5  Migraines I was originally on 100 mg but after 10 years i went to 50 mg. I was put on it for migraines when i was 4 months pregnant . I have had reduced migraines from taking pamelor. The only real side effect i had was for every 50 mg i took i gained 15-20 lbs.every time I have tried to go off of it the daily migraines have come back. It is supposed to make you tired but most meds i have an opposite effect of it so after i take it i have about 4 hours of energy. I have found to take it around 7;00 each night works best for me. I have tried several other migraine meds to help with my migraines and this is the first one that i have not grown immune to after a period of time.I have suffered from Migraines since i was four. F 46 20 years
50 mg 1X day
11/5/2013
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 3  Migraines Weight gain immediately and no real change to migraines. Helped somewhat with daily but continued severe migraines with menstrual cycle. Could not take generic and brand cost a fortune. Tried to go off after menopause and had severe anxiety and depression. Dr. Said probably could not stop taking after this many years. Have tried multiple times to ween off but haven't had any success. F 59 20 years
20 MG 1X day
10/10/2014
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 3  severe depression tiredness, vomiting, ringing in ears at first. Nightmares start and then subside with each increase in dosage, along with constipation and weight loss due to decreased appetite. Sometimes, the appetite loss runs for weeks at a time. started off with 50 mg dose and gradually increased it to 150 mg daily over the years. Scheduled to push to 200 mg daily by year's end, as depression symptoms have started reappearing. I'll need to ask my doctor just how many mg's of this stuff I can take on per day before having to switch or add meds. M 30 17 years
4/11/2007
 5  extreme panic disorder Felt a little zoned out in the morning but that side effect stopped after a week or two. I've been taking 10mg once a day for 15 years. This has been a miracle drug for me with the panic attacks. I've tryed Prosac, Zoloft and Paxil. Had very severe side affects from all of them. I have been almost panic attack free for 15 years. F 47 15 years
3/21/2007
 5  Depression/anxiety Weight gain...have gained 25 pounds in 10 years I can not take SSRI meds, and this has always worked for me. Tried both Celexa and Zoloft and they both made me very very anxious....so went back to Pamelor Have been on and off this medication for about 20 years F 52 15 years
6/21/2009
 4  depression, anxiety Yes, it's true that I've taken this medicine for over 15 years. Took a much higher dose initially (60 mg), but then tapered off to 10 mg/day (w/ option of 20 mg during high-stress times). It has been very effective for me--stopped or slowed down the panic attacks and increased my feelings that I could cope with my stressors. Eventually seemed to slowly help lift the black cloud surrounding me. Few bad side effects, except chronic constipation. Fortunately, way less noticeable negative effect on sexual function, unlike the SSRI's I tried initially. F 50 15 years
10 mg 1X day
2/9/2016
 5  ENDOGENOUS DEPRESSION CAUSES TIREDNESS IN EVENING BEST ANTIDEPRESSANT ON THE MARKET F 43 14 years
2/14/2005
 5  Anxiety & Panic Attacks Dry mouth, constipation, & weight gain(over 50 lbs) THis has saved my life! I started it about 12 years ago and even though the side effects are bothersome, they are nothing compared to the benefits of this medicine. I am on 50 mg 2x a day. I felt like my old self again. I definitely recommend this. It is also very affordable considering it is an older tryclics. I've tried a lot of the newer SSRI's but all had bad side effects. I really struggled with my weight gain, but it gave me my life back, so there was really no choice. F 33 12 years
7/27/2007
 5  Chronic Major Depression Dry mouth, sugar cravings...wt gain, constipation, crazy dreams with dose changes--only lasted 1-2 days. Pamelor (Brand name med----not generic) was the medication added to Zoloft 200mg and Wellbutrin SR 450mg that took me out of my deepest depression, allowed me to sleep soundly and be refreshed in the am, and just provided me the ability to function with ease and a positive sense of well being. Unfortunately there are side effects; however I had trialed 30 + medications and various med combinations over a painful 8 year time period; Pamelor was what it took to find normalcy. (no more crying, depressive/suicidal thoughts, irritability or insomnia.) Sorry to hear everyone else's experiences; but if it wasn't for this drug (part of my "cocktail" of 3 antidepressants)....I simply wouldn't have made it this far into my life. Age 44. As of today, my pharmacy can no longer obtain the drug!! My back up plan with 90% effiectiveness is a compounded form of Nortriptyline (generic form of Pamelor). Find an integrative doctor willing to prescribe "Nortriptyline from a compound pharmacy." They only use the "Nortriptyline" ingredient and no binders within the capsule form..........it's made all the difference in the world; but nothing beats the real Pamelor. I don't know why, but generic meds are ineffective compared to the brand name for me. Trusting compound pharmacy I highly recommend--- Abrams Pharmacy in Texas. (Only $50 out of pocket--- (-$12 shipping if you're local) F 44 12 years
30mg 1X day
11/6/2013
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 4  Depression Weight gain (20lbs), major sweet tooth, crave carbs, sleepiness after taking dose (take in the evenings), dry mouth, constipation, arrhythmias. I tried about 10-12 different antidepressants and none of them worked for me. Pamelor was the only drug that had any positive effect on my depression. When I am depressed, I stop sleeping and eating. With Pamelor, I am able to sleep and eat normally again. And that makes all the difference for me. I am a migraine sufferer and Pamelor has not eliminated my migraine attacks. Perhaps it does for others, but for me, they continue to occur regardless of being on the highest possible dose of Nortriptyline. F 36 12 years
6/22/2007
 4  depression/panic disorder constipation, dry mouth, dermatitis, rapid heartbeat This med helped me cope with a major depression/panic disorder about 13 years ago. It was most effective for the first few years. Gabapentin and alprazolam helped mitigate the anxiety. I stopped taking it over a year ago- It had outlived its usefulness. I mistakenly thought it contributed to a urinary problem (most likely was a separate- age related issue) However, the drying effects of this drug can mess with your digestive and urinary system. All in all, it was much more helpful than not- especially since I was terrified of ssri's after a miserable experience with zoloft. M 60 12 years
150mg 1X day
9/5/2010
 1  Anxiety/headaches I took it for 12yrs and it helped my anxiety and headache issue like a charm however I was very over emotional during that time and quick to fly off the handle. I didnt realize this until I went off of it last year due to increase heart palipitation that began and have since stopped since going off this. I have longterm affects from this drug, although my severe constipation i had during that time I was on it has cleared up thank goodness I have lots of urinary and stomach problems since stopping this. I feel as though this medication and its drying affect on the system created these over the long period of time i took them but didnt realize it due to nortriptyline being a pain receptor. However as soon as i went off of it everything hit me full force, constant uti's, kidney issues, pancrease issues everything in my stomach just went to hell and a year later I am still batteling this, Ive only had one doctor say that he thinks that because of the pain recepting propertys of this drug F 45 12 years
10mg 1X day
10/25/2012
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 5  headaches and mild depression None Incredibly pamelor not only reduced amount of headaches from almost everyday to 3 or 4 times per month, it also regulated my period (which i had been consulting a gynecologist for) as well as brought relief to a sun enduced skin alergy, regulated my sleep and helped me feel better overall in the mornings. F 46 10 years
7/11/2007
 4  Depression / Tension Headache Intense sedation .... dizziness when standing ... light headedness .... low sperm ejaculation .... extended orgasms. I was prescribed this for headache/chronic pain in my neck/head and major depression from having been sick for years. This drug for me worked great, not so much for my headaches but for the deep refreshing sleep it gave me to cope with the pain. It also lifted my depression and gave me extended orgasms. The only weird side effect was reduced sperm output during ejaculations. I would probably be dead if not for Pamelor. It really brought me out a sever depression. I guess for some people it works on headaches, but for me not so much. Desipramine on the other hand works good for my headaches but ruins my sleep cycle. M 46 10 years
275mg 1X day
4/27/2012
 5  Anxiety/Panic Disorder I was on 100 mg a day. I did experience weight gain. I had severe thirst and dry throat to the point of choking and have developed a habit of carrying around a route 44 from sonic all the time. (which didn't help the weight gain) Also, very sensitive to heat and my head would sweat under my hair. Pamelor would knock me out when I first started taking it. Even five years later, I slept very deeply and had a hard time waking up in the morning. If I had to be up super early for some reason, I had to skip the previous night's dose or take it in the late afternoon or I'd never wake up early enough. I have stopped taking it over the last six weeks or so. It did help so much with my anxiety and panic disorder. I would recommend it despite all of the side effects to someone with that diagnosis. F 40 8 years
5/7/2009
 4  Extreme anxiety, panic, insomnia Constipation, weight gain, dullness, "jerking" at night, laughing in my sleep (really!) In spite of the side effects, I think Pamelor is one of the best meds out there--it helped pull me out of overwhelming anxiety/depression with relatively mild side effects. I like the fact that it (or at least a pharmaceutical "close relative") has been on the market for decades, so we assume it doesn't suddenly produce bizarre or dangerous long-term effects. Also, it (or the generic) doesn't add financial stress to the patient's already-stress-filled life. Furthermore, it doesn't seem to kill off the libido like so many of my friends report the SSRI drugs like Prozac and Paxil can do. While not a euphoria-inducing "cure-all," it helped me cope, sleep, return to life. F 49 8 years
2/18/2006
 3  Migraines Knocks me out cold for hours- so i take it at night, which helps since i also have insomnia. I find that sleeping is the best medicine for Migraines, so i take Pamilar to help me sleep longer so when i wake up my migraine is gone. No side affects besides Prolonged drowsyness to the extreme! I've been taking it for about 8yrs, no complaints except i still get migraines up to 4 days a week so i don't think its helping much besides making me sleep good! F 25 8 years
4/8/2009
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 5  Migraines Before starting this medication I had migraines every day. Now, I only have them right before and right after menstruating. I haven't had any side effects, but I am on a low dose. F 27 5 years
20 mg
6/18/2013
 4  migraine drowsiness, very bad, violent nightmares It helps my headaches, but I get a bad nightmare about once a month due to the medicine. Also, night terrors- but that may not be due to Pamelor F 23 5 years
4/3/2009
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PAMELOR  (NORTRIPTYLINE HYDROCHLORIDE):  This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters) in the brain.    (Sources: U.S. Centers for Medicare Services, FDA)

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