SINEMET Reviews (LEVODOPA; CARBIDOPA)

Average Rating: 2.5 (87 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5


RATING  REASONSIDE EFFECTS FOR SINEMETCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  symptoms after Keppra increase muscle weakness in both arms and legs within 36 hours; inability to stand or walk without two large people helping to lift him up, in doctor's office, fatigue--whereas prior to drug he could walk slowly to bathrooom with a walker just fine. (In short, same results as when he tried this same drug in 2005) It concerns me that the neurologists keep pushing Parkinsons meds like this one and Mirapex on my dad. An 84-year old man with a prior cerebral hemorrhage from a vehicle accident, who's on increased Keppra dosage needed to avoid new seizure problems, plus BP meds, cholestrol drugs, Terazosin, Plavix, Zoloft and others, who also has neuropathy, severe sleep apnea and no CPAP yet (getting retested) could have increased slowness, problems walking and falls for a number of reasons. I am guessing that treatment via Parkinsons meds for symptoms of slowness and falls is likely a standard AMA protocol once someone is in their 80's, even if other causes are a possibility, especially since Parkinsons diagnosis is limited to observing visual symptoms. Therefore neurologists are afraid not to prescribe Parkinsons meds? A respected Chicago hospital had already declared my dad does not have Parkinsons disease; only features of Parkinsons (shuffling, etc.), yet once we come back home, that's all we get from the local neuros. All I can say is beware: consider looking at other causes of the symptoms AND getting other opinions before using this drug--every article I have seen written by patients/families on the internet seem to contain a number of horror stories about this drug. I'm adding ours. Our loved ones deserve better. (Time length taking Sinemet in 2009: 2 days. In 2005: about a month) M 84
3/27/2009
Email
 2  parkinson headache M 66
8/6/2009
 1  My brother takes it for Parkinson's My brother has been taking it for several years. I'm not sure of the dosage but he's 65 and has had Parkinson's since he was in his mid thirties. The side effects are terrible. He's convinced his house is full of rats - big fat ones. He's convinced people are in the garage at night starting the lawn mower over and over again. He sees people in black leotards in the hallway at night. When I try to rationalize with him that this isn't real, he just gets mad at me. M 65
not sure 5X day
10/26/2012
Email
 1  Assumed Parkinson's M 74
1X day
12/25/2012
Email

Patient History
 1  Parkinsons Like those already mentioned. Dangerous medication is my opinion after all my husband suffered taking it. WHAT IS THERE THAT A PARKINSON PATIENT CAN TAKE. MIRAPEX AND SINAMET WAS DESTRYING MY DEAR HUSBAND. HE IS OFF THEM AND IT IS THE WORST TIME IN MY LIFE WATCHING HOW BAD HE IS., WE ARE TOLD THERE ISNT ANYTHING ELSE TO GIVE HIM. MY PRAYERS FOR EVERYONE SUFFERING THIS HORRIBLE DISEASE AND I KNOW SO WELL THE PAIN YOU FEEL THAT ARE CARING FOR YOUR LOVE ONE. F 78
4X day
4/21/2013
Email
 1  Parkinson's My Husband has been taking Sinemet for about 7 yrs. Over the last year he has been having terrible confusion, insomnia and very bad dreams. We are now finding out the trouble is being caused by Sinemet. We went to a Parkinson's doctor and she told use she has heard the same comments from other patients. She said if it bothers you this much, just quit taking the medicine. So, as of today he will no longer take Sinemet. M 80
10/3/2008
Email
 2  PD My mother took her first pill this morning and then I discovered this website and after reading several posts, I'm not sure if I should proceed with Sinemet. Please feel free to contact me with suggestions or recommendations. My mother has what I would describe as "light" tremors in her hands which is a problem when she's eating. She also has problems walking sometimes. What's most important to us is that she has good quality of life. The comments about not sleeping, nightmares, nausia, etc. from taking this medication concerns me. F 75 1 days
3/19/2009
Email
 3  Depression/Anxiety/OCD a weird burny feeling in my chest, worsening of OCD symptoms, a little bit more anxiety than before, i take half of a yellow 100/25 pill ........overall, this medicine can help a little bit or a lot with the depression, but it makes anxiety and OCD worse, obviously. if u have no other options this can help with depression, but u should take it with an MAO-B inhibitor (such as selegiline or rasagiline) to prevent possible neurotoxic damage caused by the dopamine matabolism in the brain. M 18 2 days
10/6/2009
 2  Parkinson disease. 2 days
200 3X day
11/8/2016
 1  PD My father was prescribed this medicine for PD. Within 48 hours of starting to take this, he started hallucinating. He couldn't tell what was real and what wasn't real. He was convinced the police were coming to force him back to the hospital. He was up for over 30 hours conversing with people who weren't there. When I talked to him about what was or was not happening - he would sometimes say "so this is all fictitious" but then go right back into that world I couldn't see. It was horrible. I took him off the sinemet. Within 8 hours the hallucinations were completely gone. M 75 2 days
3X day
5/13/2013
 1  help with dystonia of left foot Tingling in my head and irratic heartbeat. It makes me feel like I'm going to have a seizure and or heart attack. F 23 2 days
10mg 1X day
10/18/2010
Email
 4  Restless legs daytime fatigue I've been taking just 4 days, but so far it is a godsend. I was extremely sleep deprived 5 days ago from RLS. My ferritin level is low, so I am also taking iron therapy and the hope is that in a couple months my ferritin level will be up to 50 or 60 and I won't need the sinemet any more. (RLS is rare in people with ferritin levels of 50 or more.) I am on the lowest possible dose, so I don't take it before bed, I wait till the RLS kicks in, then get up and take the Sinemet. I am usually back to sleep in 30-60 minutes. One night I slept 10 hours and it was heavenly! F 51 4 days
4/13/2008
 1  Parkinsons My brother has been taking this medicine and we have had so many problems with him, he is now in fact on remand for a crime we belive was caused by this drug, now he has spent time in a mental hospital he has been taken off this drug and is now his oldself again, This drug is awful and I would love to hear from anyone else that has experienced mental issues whilat taking, we need your help please. PLEASE HELP M 55 4 days
11/6/2008
Email
 1  suspected Parkinsons Dementia, COD, anorexia Please beware side effects M 75 7 days
1/27/2008
 1  Restless Leg Syndrome My husband took this many years ago and had extreme hallucinations--swore that things happened that no one else saw, but he wouldn't believe us when we told him that. His doctor gave it to him again recently, saying that it should be okay on this low of a dose. Not true--he started getting extremely mean, agitated, hallucinating. Pills went down the toilet--NEVER AGAIN!! M 62 21 days
30 mg. 1X day
4/20/2015
 4  Restless leg syndrome I would take one pill 3o minutes before bedtime and sleep for a good four or five hours. Then I could not get back to sleep. Now I seem to have restless legs during the day instead of just at night and on airplane trips. I like the medication for what it does for me at night but can't help but wonder if I am addicted to it inorder to get to sleep - and wonder why my legs are so antsy during the day - off and on. F 56 40 days
11/7/2008
 3  Mild parkinsons Have had a queasy feeling in stomach for 2days but not sure if its the drug.Have a tremor in one arm and its almost gone. F 55 1 weeks
Quarter 2
7/3/2016
Email
 3  Restless Legs Syndrome Augmentation, daytime sleepiness, fatigue F 43 3 weeks
7/1/2004
 3  Restless Legs Syndrome Augmentation, daytime sleepiness, fatigue Gave me 4-5 hours of continuous sleep for the first couple of weeks, now it's hit and miss. F 43 3 weeks
7/1/2004
 1  Parkinson's Hallucinations, confusion, increased falls, not recognizing family, non responsive, no appetite. After being admitted to the hospital and doctors reducing and then taking me off of this drug, I'm just about back to how I was before taking Sinemet. After seeing what I went through, my family would never recommend this medication. I don't remember a lot of what I went through other than the increase in falls and now having a broken clavicle. M 68 4 weeks
25-100mg 6X day
2/2/2017

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