SINEMET Reviews (LEVODOPA; CARBIDOPA)

Average Rating: 2.5 (87 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SINEMETCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Parkinson's Disease My Mom has severe depression and anxiety. She was originally diagnosed with PD and given Sinemet to help with slight tremor and balance issues. Has become addicted to Sinemet and can't come off of it. takes 4 pills a day. Don't believe that perscribed Sinemet has ever worked for her slight tremors. I believe it has only made things worse for her. F 77 5 years
25/100
3/2/2022
Email
 1  Parkinson's Hallucinations, confusion, increased falls, not recognizing family, non responsive, no appetite. After being admitted to the hospital and doctors reducing and then taking me off of this drug, I'm just about back to how I was before taking Sinemet. After seeing what I went through, my family would never recommend this medication. I don't remember a lot of what I went through other than the increase in falls and now having a broken clavicle. M 68 4 weeks
25-100mg 6X day
2/2/2017
 1  pd fatigue, want to sleep, insomnia, dry mouth, imbalance, fall risk, can't walk, right hand constant grasping, can't write any more, speech slurred F 58 1 years
1 pill 3X day
5/25/2016
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Patient History
 1  parkinsons totally addictive - brings on parkinsons symptoms, this is the worst drug I have ever taken M 61 5 years
10-20 4X day
11/11/2015
 1  Parkinsonism Dad is experiencing acute hallucinations, anxiety, paranoia with dosage increase. Thinks there are children in his room along with what he describes as "a menagerie". Weaning off/stopping med. and hoping the hallucinations will subside. His tremors and shuffling are minor compared to the side effects he has been having. Not glad that others had these symptoms but relieved to know Dad wasn't alone in his experience. M 78 3 months
25/100 3X day
6/30/2015
 1  Restless Leg Syndrome My husband took this many years ago and had extreme hallucinations--swore that things happened that no one else saw, but he wouldn't believe us when we told him that. His doctor gave it to him again recently, saying that it should be okay on this low of a dose. Not true--he started getting extremely mean, agitated, hallucinating. Pills went down the toilet--NEVER AGAIN!! M 62 21 days
30 mg. 1X day
4/20/2015
 1  Parkinson's disease Terrible confusion, weakness, hallucinations, difficulty in walking. Every.time I suggest that this drug is causing problems, the neurologists deny it. It is their answer to everything. I also discovered how much neurologists get from their conferences connected with drug companies. It was so discouraging to see the money they make on a drug that is causing more problems for the people who are already suffering. F 63 5 years
4X day
2/14/2015
 1  Restless leg syndrome Addiction, acute anxiety, suicide ideation, Augmentation, severe dyskenesias, weight loss, weakness and muscle loss. She became a shadow of her previous self. This drug should never be prescribed at This dosage to elderly. No help from her docs weaning her off so I moved in briefly to get her off it myself. A nightmare drug! F 88 1 years
25/100x6
7/16/2013
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 1  PD My father was prescribed this medicine for PD. Within 48 hours of starting to take this, he started hallucinating. He couldn't tell what was real and what wasn't real. He was convinced the police were coming to force him back to the hospital. He was up for over 30 hours conversing with people who weren't there. When I talked to him about what was or was not happening - he would sometimes say "so this is all fictitious" but then go right back into that world I couldn't see. It was horrible. I took him off the sinemet. Within 8 hours the hallucinations were completely gone. M 75 2 days
3X day
5/13/2013
 1  Parkinsons Like those already mentioned. Dangerous medication is my opinion after all my husband suffered taking it. WHAT IS THERE THAT A PARKINSON PATIENT CAN TAKE. MIRAPEX AND SINAMET WAS DESTRYING MY DEAR HUSBAND. HE IS OFF THEM AND IT IS THE WORST TIME IN MY LIFE WATCHING HOW BAD HE IS., WE ARE TOLD THERE ISNT ANYTHING ELSE TO GIVE HIM. MY PRAYERS FOR EVERYONE SUFFERING THIS HORRIBLE DISEASE AND I KNOW SO WELL THE PAIN YOU FEEL THAT ARE CARING FOR YOUR LOVE ONE. F 78
4X day
4/21/2013
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 1  Parkinson's Terrible hallucinations, paranoia, weight loss, thirst for cold water, crazy dreams, anxiety, aggressiveness. After 3 years Sinemet has made my husband insane! If I up his dose even a little he says he feesl like he wants to crawl out of his skin. He feels like my son and I are his enemies when all we are trying to do is help him. Most of the time he can not be reasoned with. His doctors are not helpful. Life is a living hell! M 61 3 years
10mg 3X day
2/19/2013
 1  Assumed Parkinson's M 74
1X day
12/25/2012
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Patient History
 1  parkinson like symptoms Was taking 3 half pills a day, did stop the tremors, then DR upped it to 1 full pill 3x a day, started suffering from extremely detailed, terrifying hallucinations, confusion, tremors, complete madness, seemed like living in a parallel universe where no-one could hear me, had to throw myself on the floor to make sure I was awake, couldn't take care of myself, tell what time of day it was, talked to my dead wife's ghost, people were sitting on my bed talking to me that no-one else could see. Stopped taking sinemet, dr prescribed it for minor tremors and stiff gait, have none of those symptoms currently, no longer hallucinating, no longer confused, no tremors, able to function far better than before I started taking the drug - will not take it EVER again. Went against Dr's orders to stop taking the drug, and glad that I did. M 69 5 months
10mg 3X day
11/15/2012
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 1  My brother takes it for Parkinson's My brother has been taking it for several years. I'm not sure of the dosage but he's 65 and has had Parkinson's since he was in his mid thirties. The side effects are terrible. He's convinced his house is full of rats - big fat ones. He's convinced people are in the garage at night starting the lawn mower over and over again. He sees people in black leotards in the hallway at night. When I try to rationalize with him that this isn't real, he just gets mad at me. M 65
not sure 5X day
10/26/2012
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 1  Parkinson's Disease Absolutely horrible nausea all the time. Neurologist tried adding Lodosyn to reduce nausea with no luck. Also weak with profuse sweating. Tried everything to get rid of nausea - ginger products of all types, eating protein 30 minutes after med. Nothing worked. Had to be taken off of it. I'd rather shake than be so nauseated I'm dysfunctional Would not recommend unless you like being nauseated all the time. F 53 1 months
25/100mg 3X day
10/5/2012
 1  PD This drug combined with depression causes many problems with my mom. I feel the Dr. over prescribed this drug and my mom became addicted. She was obsessed with getting her pills on time. The hallucinations this drug causes for my mom are horrible. She is like a schizophrenic now thinking that everyone is out to get her. At 62 my dad did not want to take care of her so she ended up in a psych ward at 62 and than a dementia nursing home ward. STAY OFF THIS DRUG AS LONG AS POSSIBLE. F 67 10 years
10X day
7/8/2012
Email
 1  Parkinson's Disease Dystonia in left leg, with toes curling, foot twisting at the ankle, aching leg, cringing feeling in ankle/foot and difficulty walking. I had very minor Parkinson's symptoms. After about 3 months the dystonia started. I thought it was the Parkinson's worsening. The neurologist suggested increasing the dosage and it seemed to make things worse, and I started noticing the dystonia would come & go depending how long it had been since I'd taken the medicine. The doctor suggested botox injections in my leg which didn't appeal to me. After much research in books & on the internet, I began to suspect the medicine was causing the dystonia. I told the doctor I wanted to stop the meds & got instructions on how to stop it. The dystonia is gone and I feel great. It was much worse than my current symptoms. F 60 7 months
25/100 3X day
4/6/2012
Email
 1  Osteoperosis My father has been taking Sinemet for 5 years. He has experienced dreadful hallucinations, paranoia and psychosis. Shocking visions of ugly monsters and people trying to murder him and his loved ones. If he had alcohol at his disposal he would have become an alcoholic too, there we're signs of additiction type of behaviours. My father began taking this drug at the age of 80 and we believe he was overmedicated by the nursing home he was living in. This high dose has now caused terrible mental problems for my father that he would have been better off without it and at least sane. M 86 5 years
250mg 4X day
5/21/2011
 1  help with dystonia of left foot Tingling in my head and irratic heartbeat. It makes me feel like I'm going to have a seizure and or heart attack. F 23 2 days
10mg 1X day
10/18/2010
Email
 1  parkinsons hallucinations...confusion..joint pain.. upset tummy..depression moody sickness insomina nightmares my dads been taking these meds for 3 yrs and has ended up in a terrible state constant hallucinations..sickness somnia depression his had to stop driving and hasnt been out of the house for a year... also i find theres not much help out there within the nhs for people with parkinsins his had parkinsons sine he was 53 12 yrs now its a horrible diesease that slowly takes the person u onced knew and loved x M 65 3 years
3X day
8/4/2010

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