SINEMET Reviews (LEVODOPA; CARBIDOPA)Average Rating: 2.5 (87 Ratings)Filter ResultsCompare SINEMET with similar:
Type: Rx Drug
|
Results are sorted by Satisfaction highest to lowest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SINEMET: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SINEMET | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | RLS | Only side effect has been some nausea but have learned how to deal with that. This drug has helped me get rest at night by keeping my legs still. Highly recommend this drug for RLS. | F | 42 | 1 years 100mg | 2/7/2017 | 5 | dopa responsive (partial) dystonia | Nausea and feeling rotten when first taking in morning, coming off effect, however if you take them correctly and with having something to eat (do not take on empty stomach) it's fine. It's been a great medicine for my family and I having a dominant gene. If we didn't have this medicine we would probably not be able to walk and be in much more terrible pain. | F | 37 | 1 years 6x62.50dai | 8/22/2014 | 5 | PD | Provider reduced sinemet while in hospital from 9 pills/day to 4. Side effect is inability to stand or walk, very unstable blood pressure. | it keeps abnormal thoughts to a minimum in combination with seroquel at bedtime. While sinemet is working, thoughts are normal and able to function | F | 83 | 2.5 years 25-100 3X day | 6/29/2012 | 5 | Restless Leg Syndrome | Works wonders. After 2 years use, I now need two tablets instead of one, but no noticeable side effects. | M | 63 | 2 years | 1/29/2007 | 5 | Parkinson's | None cause I started very slowly with much less than prescribed to allow my system to get used to it. | Very good / very bad. Classical situation where a drug seems to address exactly what is going wrong in the Parkinsonian's brain and that is the diminishing capacity to make our own levodopa (which is what sinemet is). Levodopa in a healthy person is made in our bodies from basic nutrients. Levodopa, in turn, is converted to Dopamine, which in balance with two other neurotransmitters, acethylcholine and GABA, provide for smooth and controlled movement. Throwing ready-made levodopa into our bodies causes a well known pharmacological effect called | F | 48 | 7 years | 6/10/2005 | 5 | restless leg syndrome | possibly night sweats, they started about the time I started the medication. The sweats could be from thyroid. | Before I started taking Sinemet, I could not sleep for all the jerking motions of my legs. That problem doesn't exist with the medication. I take one every night 30 minutes before going to bed. | F | 47 | 7 years | 4/30/2005 | 5 | Young Onset Parkinson's | Occasional dyskenesia if I dont dose correctly, ON/OFF periods | Saved my life! I medically retired at 33 from the Air Force. SINEMET is the medicine that helped, all the agonists had extreme side effects. SINEMET has allowed me to go back to work as an IT specialist. | M | 38 | 5 years | 1/11/2005 | 4 | Parkinsons | Nausea, insomonia, | M | 49 | 4 years 25/250 mg | 3/22/2017 | 4 | Parkinson's | Severe, chronic nausea Frequent vomiting Severe fatigue starting 30 minutes after each dose | If this medication were not saving my life, I would never, ever take it. | F | 63 | 3 months 150/50 2X day | 12/4/2016 | 4 | diagnosed with PD 39 years ago | I have all the side effects that you have with Sinemet also I take Comtan along with the Sinemet. . the last few years I have a lot of sweating as the drug wears off & before I can take the next dose. As the next dose takes affect my sweating just stops instandly until it starts wearing off again .That is the worst side effect that I have after all these years. | F | 69 | 39 years 100/250 7X day | 2/16/2016 | 4 | Parkinson's | Difficulty walking right leg leans toward left leg. Had left hip replacement and is doing well. | Just lately last few days started taking flexerell and also celebrex foir back spasms. | M | 77 | 2 years 100mg 3x d | 9/18/2015 | 4 | ideopathc young onset parkinsons | start of dose dyskinesia and severe dyskinesia at end of dose (evenings)Very tired during day,lack of energy and self motivation.. have now developed a new symptom -over-breathing whilst having evening dyskenesia which leaves me breathless till I fall asleep.I presume it is from all the exertion and ballistic movements. | i still have relatively good results from my sinemet (high dose)I have a lot of freezing episodes now lately even if i am "on"I know there is no way I can reduce my dose because if I start fluctuating, I will experience these horrible dyskinesia's. I know most pd patients that suffer from dyskinesia gets the peak dose variant-I get the diphasic type which come in effect when my brain reaches certain (low) levels of levadopa (dopamine).There is no effective treatment yet and it leaves most specialists puzzled,The doctors always say to come down with the dose, but it is wrong to compare this type of dyskinesia with "peak dose" dyskinesia as it seems to work just the other way around. amantadine also has no effect on this type of dyskinesia.Lowering the dose of sinemet is also disastrous because then I experience more fluctuations and dyskinesias.My Doctor once made the following remark." we'll have to come way down with your dose,you don't need to be Tarzan the whole day"My word! As I still contribute to the household as a whole and my sinemet still carries me through the day albeit a high dose,I cannot go into total freeze- up, or suffer with the low dose fluctuations/dyskinesias I am afraid adding agonist medications will just prolong the dyskinesia when I take my last dose of sinemet in the evening. I know there is some research going on long time in finding a treatment for this side effect,and that some anti epileptic medications shows pr | M | 59 | 7 years 25/100 8X AN | 5/15/2015 | 4 | for Parkinson's | I get spells where my jaw gets stiff, my hands get stiff, my toes curl up, I have difficulty walking, my blood pressure goes up, i sweat and have to lay down. Doctors can't figure it out. I was doing okay until I got the flu last January and have been miserable ever since. One doctor went so far as to tell me I don't have the disease because my brain MRI does not indicate such. | F | 76 | 14 years 25 - 100 9X day | 12/5/2014 | 4 | Dopamine responsive dystonia | None at first as dose was increased slowly. Main side effect now are sickness and yawning fits. It stops tremor, releases tension in neck, stops twisting of foot, takes hand out of a dystonic hold. Allows me to function without my body feeling it is 100 years old. Must be taken on time with no gaps. Downside was i could never get them out the packet as they were so small. Dosage increased so now take co careldopa. | F | 38 | 2 years | 8/25/2014 | 4 | Pd | Confusion joint pain sleepless constipation greed impulsive | M | 55 | 2 years 25/100 | 1/3/2014 | 4 | parkinsons | I have so far Gained from this medicene. I do find myself bored alot. but I live in the country an its quite here. | F | 52 | 3 months 10/100 4X day | 7/22/2011 | 4 | Sinemet | weight gain, sleeping problems | Works well for me so far. I also take Mirapex so don't know if Sinemet is helping or not, but with the minimal side effects, I will continue taking it. | M | 59 | 6 months 25/100 mg. 3X day | 2/19/2011 | 4 | Parkinson's | Initial nausea, burning and bad taste in mouth, and some trouble sleeping. | HANG IN THERE if you can. Sinemet did improve my PD symptoms but it did take about six long weeks to get passed the nausea and some of the other side effects...I had to give it (Sinemet) a chance and just put up with the bothersome side effects for a while. I did find that taking the pills with a full glass of warm water and not taking them on an empty stomach did help. Sugar-free hard candy also helped with the bad taste in my mouth. Currently, I am in the process of adjusting the dose and adding an agonist (Requip) at bed time to find the right combination and dosages to best address my symptoms. Summarily, response to this medication appears to be variable just like the symptoms of PD. | M | 62 | 5 months | 4/6/2009 | 4 | Restless leg syndrome | I would take one pill 3o minutes before bedtime and sleep for a good four or five hours. Then I could not get back to sleep. Now I seem to have restless legs during the day instead of just at night and on airplane trips. I like the medication for what it does for me at night but can't help but wonder if I am addicted to it inorder to get to sleep - and wonder why my legs are so antsy during the day - off and on. | F | 56 | 40 days | 11/7/2008 | 4 | Young Onset Parkinson's | Brief stomach upset when taken in the morning. Dosing is tricky. Restless when taken too much; very evident when it wears off. Flatulence (yuck), daytime sleepiness, nighttime insomnia, and some memory issues. | I started tremoring at age 27. I was diagnosed with essential tremor for a long time. My symptoms got progressively worse until it became difficult to function. After suggesting PD to my doctor for over a year, I finally got properly diagnosed. Sinemet has made my life so much better. I'd take the side effects over the inability to write, walk, and engage in normal life activities ANY DAY! | F | 35 | 4 months | 7/2/2008 |