SINEMET Reviews (LEVODOPA; CARBIDOPA)Average Rating: 2.5 (87 Ratings)Filter ResultsCompare SINEMET with similar:
Type: Rx Drug
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Results are sorted by Gender with females listed first (reviews with no gender reported listed before females). Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SINEMET: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SINEMET | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 2 | Parkinson disease. | 2 days 200 3X day | 11/8/2016 | 5 | RLS | Only side effect has been some nausea but have learned how to deal with that. This drug has helped me get rest at night by keeping my legs still. Highly recommend this drug for RLS. | F | 42 | 1 years 100mg | 2/7/2017 | 5 | PD | Provider reduced sinemet while in hospital from 9 pills/day to 4. Side effect is inability to stand or walk, very unstable blood pressure. | it keeps abnormal thoughts to a minimum in combination with seroquel at bedtime. While sinemet is working, thoughts are normal and able to function | F | 83 | 2.5 years 25-100 3X day | 6/29/2012 | 5 | Parkinson's | None cause I started very slowly with much less than prescribed to allow my system to get used to it. | Very good / very bad. Classical situation where a drug seems to address exactly what is going wrong in the Parkinsonian's brain and that is the diminishing capacity to make our own levodopa (which is what sinemet is). Levodopa in a healthy person is made in our bodies from basic nutrients. Levodopa, in turn, is converted to Dopamine, which in balance with two other neurotransmitters, acethylcholine and GABA, provide for smooth and controlled movement. Throwing ready-made levodopa into our bodies causes a well known pharmacological effect called | F | 48 | 7 years | 6/10/2005 | 5 | restless leg syndrome | possibly night sweats, they started about the time I started the medication. The sweats could be from thyroid. | Before I started taking Sinemet, I could not sleep for all the jerking motions of my legs. That problem doesn't exist with the medication. I take one every night 30 minutes before going to bed. | F | 47 | 7 years | 4/30/2005 | 5 | dopa responsive (partial) dystonia | Nausea and feeling rotten when first taking in morning, coming off effect, however if you take them correctly and with having something to eat (do not take on empty stomach) it's fine. It's been a great medicine for my family and I having a dominant gene. If we didn't have this medicine we would probably not be able to walk and be in much more terrible pain. | F | 37 | 1 years 6x62.50dai | 8/22/2014 | 4 | for Parkinson's | I get spells where my jaw gets stiff, my hands get stiff, my toes curl up, I have difficulty walking, my blood pressure goes up, i sweat and have to lay down. Doctors can't figure it out. I was doing okay until I got the flu last January and have been miserable ever since. One doctor went so far as to tell me I don't have the disease because my brain MRI does not indicate such. | F | 76 | 14 years 25 - 100 9X day | 12/5/2014 | 4 | Dopamine responsive dystonia | None at first as dose was increased slowly. Main side effect now are sickness and yawning fits. It stops tremor, releases tension in neck, stops twisting of foot, takes hand out of a dystonic hold. Allows me to function without my body feeling it is 100 years old. Must be taken on time with no gaps. Downside was i could never get them out the packet as they were so small. Dosage increased so now take co careldopa. | F | 38 | 2 years | 8/25/2014 | 4 | Restless legs | daytime fatigue | I've been taking just 4 days, but so far it is a godsend. I was extremely sleep deprived 5 days ago from RLS. My ferritin level is low, so I am also taking iron therapy and the hope is that in a couple months my ferritin level will be up to 50 or 60 and I won't need the sinemet any more. (RLS is rare in people with ferritin levels of 50 or more.) I am on the lowest possible dose, so I don't take it before bed, I wait till the RLS kicks in, then get up and take the Sinemet. I am usually back to sleep in 30-60 minutes. One night I slept 10 hours and it was heavenly! | F | 51 | 4 days | 4/13/2008 | 4 | Restless leg syndrome | I would take one pill 3o minutes before bedtime and sleep for a good four or five hours. Then I could not get back to sleep. Now I seem to have restless legs during the day instead of just at night and on airplane trips. I like the medication for what it does for me at night but can't help but wonder if I am addicted to it inorder to get to sleep - and wonder why my legs are so antsy during the day - off and on. | F | 56 | 40 days | 11/7/2008 | 4 | Young Onset Parkinson's | Brief stomach upset when taken in the morning. Dosing is tricky. Restless when taken too much; very evident when it wears off. Flatulence (yuck), daytime sleepiness, nighttime insomnia, and some memory issues. | I started tremoring at age 27. I was diagnosed with essential tremor for a long time. My symptoms got progressively worse until it became difficult to function. After suggesting PD to my doctor for over a year, I finally got properly diagnosed. Sinemet has made my life so much better. I'd take the side effects over the inability to write, walk, and engage in normal life activities ANY DAY! | F | 35 | 4 months | 7/2/2008 | 4 | Frequent, severe muscle cramps | Mild constant backache/night sweats | Don't like the backache or the night sweats, but so far, this is the only thing that has helped alleviate most of the cramps I was getting in the muscles of my legs, feet, arms, and hands. | F | 57 | 10 months | 11/15/2006 | 4 | Young onset Parkinson's disease | It is the Gold standard of PD drugs for me, it helps tremor or the lack of movement, it is a good drug but it has an = on /off phenomena after 3-6 years, to much can be as bad as not enough. | Sinemet is a good medication for me, yet it is not a cure. | F | 37 | 7 years | 9/28/2004 | 4 | parkinsons | wearing off | F | 10 months | 10/2/2004 | 4 | Parkinsons | None noted. | F | 66 | 4 years | 4/17/2006 | 4 | parkinsons | I have so far Gained from this medicene. I do find myself bored alot. but I live in the country an its quite here. | F | 52 | 3 months 10/100 4X day | 7/22/2011 | 4 | Parkinson's | Severe, chronic nausea Frequent vomiting Severe fatigue starting 30 minutes after each dose | If this medication were not saving my life, I would never, ever take it. | F | 63 | 3 months 150/50 2X day | 12/4/2016 | 4 | diagnosed with PD 39 years ago | I have all the side effects that you have with Sinemet also I take Comtan along with the Sinemet. . the last few years I have a lot of sweating as the drug wears off & before I can take the next dose. As the next dose takes affect my sweating just stops instandly until it starts wearing off again .That is the worst side effect that I have after all these years. | F | 69 | 39 years 100/250 7X day | 2/16/2016 | 3 | Mild parkinsons | Have had a queasy feeling in stomach for 2days but not sure if its the drug.Have a tremor in one arm and its almost gone. | F | 55 | 1 weeks Quarter 2 | 7/3/2016 | 3 | Parkinson | Pins and needles in my feet making it hard for me to walk. Feeling sick. Sleepless nights. | I think that Sinemet should be taken off the market.It is clear that it is making people more ill than better. My brother took sinemet unfortunately he passed a away in February age 46 he been taking Sinemet for 10 years he always said that they were making him feel a lot worst,but he would not stop taking them because the doctor told him to take them,and my brother always said that the doctor knows whats best.He sufferd. | F | 47 | 2 years 62.5 3X day | 5/18/2010 |