DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth control Im 18, just got my first shot in september. it is now the end of october and i have experienced all of the following: Extreme Mood swings, Depression, Increased apatite. I just recently started spotting and had continuous extremely painful cramping all day yesterday. My clear skin now had breakouts all the time. If i would have known all that woud happen before i got the shot, i woud never have gone through with it. it may be hassle free & easy, but the things you go through for it, isn't worth in the long run. F 18 2 months
 10/25/2009
 1  Only option for birth control No sex drive,moodiness and very vile attitude,too many hot flashes and severe cramping. If I had found this site before my first shot there is no way in hell I would have taken it.I got my first shot 8-20-09 and on 8-31-09 I started bleeding and 56 days later I am still bleeding,some days so heavy I use diapers to keep from bleeding all over the place.In two months times I have purchased 7 months worth of pads and tampons,I am afraid to leave the house out of fear of soiling my clothes.I started my first period when I was 12 and never had a cramp in my life,noe the cramps are so bad I just sit/lay in bed,hold my stomach and rock.My patience is short and everybody I know has started calling me mean,thank God I don't own a gun.The only reasons this works as birth control is because,#1.you are bleeding everyday,#2.your attitude is so stank,no man will come near you,#3.You have no desire to have sex and #4.If you have a man he will leave you beacuse no man will believe that his woman is having a 56 day period,I will definitely not be taking the second shot,I would rather have 20 kids than to go through this.The prayer that I pray everyday,all day is Lord please stop the bleeding.Thank you for such valuable information and I am so glad that I am not alone in this. F 46 2 months
 10/25/2009
 1  pregnancy prevention acne, headaches, increase appetite, no sex drive, discharge, nausea, weight gain, moody, and tired i had the worst headache yesterday i have only had 2 shots and the first one i did fine with but the second really changed me i have discharge now, i am very hungry all the time i have gaind like 10 pounds in 2 minths i have acne and i have never had acne in my life i feel sick all the time and sleepy and old F 21 2 months
 9/30/2009
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 1  birth control and regulate periods prolonged bleeding never satisfied when i ate sleepy moody and decreased sexdrive. as soon as i got on depo 2 weeks later i got my period and it lasted for a little over 2 months and withing the first month the doctor gave me a second depo to stop the bleeding it didn't work. i got 2 shots in 2 months. here i am 5 months later and i may not be able to have children because of this i have ovarian cysts and a uterus thats so thin it's laying on my back. needless to say if you cant take it out right away dont take it at all. i dont wish this pain on anyone. F 24 2 months
 10/4/2009
 4  birth control bone-joint aches severe fatigue nervousness no weight gain, but I cant loose my pregnancy wieght I have only had one shot so far, and I wasn't informed by my dr at all. But after looking up side effects I realize that the pain that I have been feeling in my bones and joints which worsens after a short walk is due to the shot, also lately I have been experiencing severe fatigue, like 12 to 14 hours of sleep whenever possible. F 23 2.5 months
 6/25/2007
 1  Birth Control slight headaches, cramps, period!, irritability out of the wazoo!! mood swings, random crying, laziness, i'm lethargic and unmotivated all the time, weight gain, etc. I'm getting married in a matter of days, and i started taking Depo 2 1/2 months ago so my body could be used to it... little did i know I would start a period and still be on it, so far a week later. And my poor family! This should be a happy time, but I get pissed at everyone for everything. I have never disliked people more, and I tend to snap on people where I used to be really laid back and apathetic towards most things. Then I randomly start crying- and I-- am NOT a crier! I hate crying, and i hate it more since I don't do it by choice-- it's just something that happens... My doctor said it would take some time to get used to it,and my friend said her moodiness went away after a few months... but I don't think all this is worth the high guarantee of not having a baby. gosh... I think I'd be less stressed if I had a baby! I'd probably cry less than I do now and not be so angry, let's hope. Regardless... I don't think I'm going to take the shot next week, and I will probably start F 19 2.5 months
 12/3/2008
 5  birth control brief spotting, annoying at first, but it never returned i've had very little problems with the shot since i've taken it. i've gained weight, but i've had problems with that way before i started taking it. i can't say that i'd recommend it to anyone because not everything is suitable for everyone. i didn't have any problems before taking it and my body's adjusted to it since. not everyone's body will be right for it...and all side effects aren't necissarilly caused by the shot, some people might've had previous problems to begin with. so far, it's only benefitted me. F 17 3 months
 6/23/2007
 5  Doctor recommendation. weight gain of 20 lbs, a 3 month long period (still hasn't ended), may be cause of weakened immune system, moodyness, back pain, acne, extreme fatigue. I only rated 5 to get at top of the lost. Depo should be banned from the market! The side effects are insane! I was only 14 when I got recommended the shot. My mom said it was just that time to look at my options. Well, my doctor recommended the Depo shot. She said side effects of 5 lbs weight gain (10 lbs at most), and that was it. She said my period would stop a few days after the period. What a joke. I gained 20 lbs in the first month! I now eat salads and have changed my diet and still no weight gain. I hope when I put up my pool that will help with the weight loss. Also, after the shot my period did stop. Only to come back a month later and it hasn't stopped since. My period started Dec. 26. It's now March 16 and I still have this wreched period that I was not informed I would possibly get. I also have extreme fatigue, which has pretty much ruined my Freshman year. I'm always too tired to go anywhere. I'm a straight A student and because of my fatigue and slight depression from th F 15 3 months
 3/16/2007
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 5  Birth Control Weight gain, ovarian problems, menstrual cycle that lasted for 4.5 months straight! You can go to fda.gov and file a report to help get the drug off the nasty Depo off the market. I and several others have. The more people to do it, the more serious they will take it. Please do this. F 15 3 months
 5/7/2007
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 5  Prevent Pregnancy Unexplained bruising. I started Depo in November when I got fed up with the ring. I've been on various birth controls since I was 15 and I think this is the best yet. As a person who has migraines with aura, it was important for me to go on a non-estrogen birth control. I'm too busy for mini-pills, and after talking with my doctor, I got my first Depo shot. I was very reluctant after reading about all of the weight gain, mood swings, and bone density loss. My only other choice, really, was an IUD...An idea I wasn't fond of either. Within three days of receiving the shot, the two month long bleed-a-thon I experienced while on the Ring stopped and I've had light spotting only twice in three months. I have gained no weight...in fact, I think I've lost a little weight! I've had no headaches, and I can't blame the shot for my moodiness. My libido has increased since coming off the Ring and I have natural moisture again. The only negative side effect I've noticed is a tendency to bruise for no apparent reason. I've always tended to be anemic, so I'm hoping that increasing my iron and calcium will combat this problem. Otherwise, I've been incredibly happy with the shot. F 29 3 months
1X AN		 1/31/2011
 5  In the Upper Arm AMAZING - I ABSOLUTELY LOVE IT When I tool my first shot I will admit I was engaged to get married, and a month later I wasnt anymore =D lol but were still togeather. I had mood swings, and Lashed out at people, and some moments I could have beat my Fionce up, and the poor man didnt do anything. I will be honest I WASNT myself .... But My doctor said to just give it a couple trys. So since then I have had 2 shots and I feel great. I dont have mood swings, No periods, No Spotting Nothing. MY Sex Drive is amazing, When I first took the shot I weighed 186 and now I weigh 160... I feel amazing. After that second shot everything adjusted and fell into place! And ive yet to get pregnant! Wich is the best thing... F 20 3 months
1X day		 5/19/2011
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 5  Prevent pregnancy Have had no issues have lost weight, have had prolonged period but not heavy. No more migraines, feel great. Not for everyone but I've tried them all and this is the best for me F 33 3 months
 2/12/2012
 5  Bad Cramps/ Birth Control I crave certain foods at times, that's all. I love it! My cramps were unbearable and now I'm fine! F 18 3 months
n/a 1X M		 11/28/2011
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 5  bad headaches.migaines.crampin Well I had bad headaches and crampin bad befo I started usin depo....period was heavy in would get so upset.in flash out.but er since I took depo it world miracles ilove it nomre periods jsst spotted too weeks after gettin ma shot in ma right bootock spotted for 'bout three weeks but cnt complain. F 22 3 months
2		 12/2/2012
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 5  Birth Control Spotting alot in the first month, spotting/bleeding after sex-3 months on is still happening, slight increase in acne, (but far less acne than the week around my period when i was taking the pill). All in all so far I'm pleased with Depo. Yes there are side effects and I understand that the severity of the side effects depends on person to person. The spotting/bleeding after sex is the worst thing I've experienced so far (try explaining it to your boyfriend!)My docor says that within the first 3 injections these side effects will stop, I do hope so! F 27 3 months
 6/11/2006
 5  BIRTH CONTROL NO PERIOD CONTINUOUS PERIOD FOR 6 MONTHS. SEVERE ANXIETY AND DEPRESSION THIS SHOT HAS RUINED MY LIFE. I DIDNT KNOW WHAT COULD BE WRONG WITH ME UNTIL I REALIZED WHAT IT HAS DONE TO OTHER WOMAN. I USED TO BE HAPPY AND UPBEAT AND LOVING LIFE. I HAVE A WONDERFUL BOYFRIEND AND FAMILY. GREAT JOB NO WORRIES WHAT SO EVER BUT BECAUSE OF THIS SHOT I HAVE STARTED HAVING AWFUL MOOD SWING AND DEPRESSION. I WORRY ALL THE TIME ABOUT NOTHING AND HAVE NOT STOPPED BLEEDING SINCE JUNE. IT IS NOW NOVEMBER! I WILL STOP USING THIS SHOT AND HOPEFULY WILL BE MYSELF AGAIN IF NOT ITS GOING TO RUIN MY RELTIONSHIP WITH THE MAN OFMY DREAMS AND RUIN MY CARREER AND THE DRIVE I USED TO HAVE FOR LIFE. DOCTORS SHOULD BE ASHAMED OF THEMSELVES AND THE FDA NEEDS TO DO THERE JOB BETTER!!!! WHATS IT GOING TO TAKE TO MAKE THEM REALIZE WHAT THERE DOING TO POOR WOMAN. DONT RUIN YOUR LIFE WITHTHIS SHOT!!! F 22 3 months
 10/27/2005
 5  prevent pregnancy ACNE, fatique, loss of sexual desire, vaginal dryness, spotting I was very happy with Yasmin but only tried the depo shot out of interest of not having a period or having to remember a daily pill. Since I have received the shot I have been extremely fatiqued and (NEVER had acne before-not even in highschool) am now battling acne! I have also put on 5 lbs. For the last two weeks I have been consistently spotting. I will NOT use Depo again and am already going back to Yasmin (a mild daily pill). I have heard of MUCH worse horror stories, PLEASE do yourself a favor and research Depo or any drug before trying it. F 34 3 months
 4/22/2006
 5  Because i was stupid i got depression and anxiety which i had never suffered before the shot, I'd never recommend it F 38 3 months
 6/6/2020
 4  A safety net to fall on I wake up every morning & have hot flashes. My legs hurt randomly. My back hips hurt randomly sometimes too. I could just be laying or sitting down & they start to hurt. I haven't had any periods. Maybe a week or less on being on the drug I had a little bit of spotting but haven't had any again. My right arm where I got the shot injected also hurts randomly. It's the feeling of it being sore from barely getting the shot but the pain comes every so-often. Ive had some mood swings. I don't think I've gained or lost any weight I've stayed the same. It's not all that bad, it keeps me protected bc I have had sex and I'm not as worried or paranoid. Overall it's not horrible, I suggest it for girls my age bc we may tend to forget to take the pill. It's not horrible bc I don't ALWAYS feel these side effects. They're all an every so often thing. I do recommend the shot. F 15 3 months
 3/25/2017
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 4  Birth Control I haven't noticed any weight gain. My friend mentioned the other day that it looked like I had lost some weight though I've started excercising and eating right so I don't think it has to do with the shot. Some spotting that I think will go away. Biggest thing is the acne...I never had acne before. Now I keep breaking out. It's driving me nuts! I've liked not getting periods; my periods are usually pretty heavy. I haven't noticed any weight gain and I'm not particularly worried about it; if I gain weight then I'll just eat less and work out more to lose it. (Burn more calories than you eat=weight loss people, it's not any more complicated than that). I don't like the zit problem. I used to have problems with dry skin, and now it's oily all the time. This is the biggest drawback. I haven't noticed any problems with depression or anything like that, but I've only been on it 3 months. The bone loss has me a bit concerned (even though I work out and take in more calicum). Between that and the oily skin, I'm not sure if I want to stay on it or not. But not getting your period is nice! I'll have to think about it some more. I'll probably stay on the shot until I'm done with boot camp so I don't have to worry about periods and stuff. Then go back to the pill for health reasons. F 22 3 months
 6/5/2006
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