DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  birth control Manic weight loss, racing heart and palputations, stiff neck, extremely tired all the time, very irritable, chest pain, dead legs, spots, extreme loss of sex drive - non exsistant, increased appetite but am loosin weight rapidly, depressed, majoryly stressed all the time. I am 26yrs old and only weighed 8 and half stone before takin this drug. in the space of 2 wks i am now only 7stone. i get really bad chest pains going through to my shoulder. i have almost passed out and went a yellow colour. i suffer with anxiety anyway and it seems to have emphasized depressing feelings. my sex drive has completely gone, i tried it a few weeks ago and it felt completely wrong to the point where i felt dirty. i am snapping at my toddler and my partner. I am gettin really BAD night sweats to the point where i have to change my bed clothes the sweat is literally running off me. through the day i am shivering from cold and then randomly get a hot flush. i am eating more and more, the more i eat the more i seem to get hungry and i cant keep the weight on me, i have 2 children and dont have the energy to be the mother i was before having this horrible injection. i am only half way through my first shot and have to put up with this nightmare for another 6wks! Am definate F 26 6 weeks
 3/9/2009
 1  Way too many side effects. I have taken the depo shot in the past w/ no side effects other than gaining weight. My period is very heavy, soaking a "super" tampon in under 45 minutes for 4-5 days straight. So, I went on depo. I was actually on my period the day I got the shot, and the bleeding stopped immediately. So far, so good. I have had a lot of issues lately, and, after doing research, see that many of them can be traced to Depo: Hot flashes--I sweat at work every time I go in, while others are cold. I'm talking SWEAT--it's very uncomfortable & icky. I had what was described as a panic attack--I ended up going to the ER, b/c I thought I was having a heart attack, had all the classic symptoms. They told me everything was normal, and asked if I'd ever had a panic attack, which I haven't. Irritability. Headaches. Had sores in my mouth and tongue, looked like the skin was sloughing off. Diagnosed as erythema multiforma. Now, since Sunday night, I have had blurred and/or double vision. I can't even F 34 6 weeks
 10/19/2007
 1  For extreme period pain EXTREME mood swings, no energy/weakness, lightheadedness, heavy bleeding, rash, constant pain in my abdomen I was given this injection as I was told it could help me with my periods which are incredibly painful. I was told to expect some spotting and that was it. For the first 2 weeks after the shot everything seemed okay, I then developed a rash that went from my feet to my knees and from my hands to my elbows, antihistamies stopped the itch but the rash didn't go away for about 1/2 a week. Then I started to bleed. Not spotting. Proper HEAVY bleeding, clots and all. Initially I was in less pain than I would have been prior to having the shot, but by day 10 of the bleed, my pain was increasing more and more to a point where I was having to take the same old regimen of painkillers as I had done prior to the depo. Eventually the bleeding pettered out after 11 days, but I am left with constand and really bad pain in my pelvis, in the same 2 locations I have always experienced pain, and despite the fact the bleeding has stopped I am still on high strength painkillers for this pain and I don't know when it is ever going to stop. I also have a lot less ebergy than usual; I was running 20k a day on my crosstrainer but now I struggle to stand up from the setee without a wave of lightheadedness hitting me. The bleeding has caused me to go anaemic again (so much for light to non-existant periods!!) I also had the most unbalanced mood swings about a week prior to, and during, my 11 day bleed, ranging from feeling suicidal to teary, angry, all very negative. I wish I had never had th F 33 6 weeks
1X O		 6/16/2010
 1  I'm anemic I have had bleeding for over three weeks now. I did the Depo Provera shot ten years ago and never had side effects. But now...I'm moody...bleeding...extremely tired because I'm anemic to begin with...and NO ONE told me this drug could affect my hepatic levels...which is not good since I've been treated for Hep C. Would NOT recommend this shot to ANYONE!! F 39 6 weeks
1X O		 9/23/2011
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 1  Long(er) term birth control Long, drawn out period. Severe depression. Suicidal thoughts. Mood swings. Weight gain. Appetite change. Stomach ulcers. ZERO sex drive. I got this shot at my local Planned Parenthood after talking to the nurse about different options. I had done some research on the shot, but without knowing WHAT symptoms to type in, all I was finding as a side effect was "weight gain," which the nurse assured me would be 5lbs average. Within 2 weeks of getting the shot, I fell into a deep, dark depression, and within the last week I have been having suicidal thoughts. Never before in my life have I felt like this. My fiance is worried about me and told me basically whoever I am, it's not me. He knows it's the drug, but there have been moments where I wanted to call it quits with us (again - NEVER before) just because of my severe mood swings. My period is non stop now for 9 days and doesn't look like it's stopping any time soon. My sex drive is ZERO. Not only is it just not there - but the fact that I have gained almost 10lbs in SIX WEEKS, and the fact that I am constantly on my period, just makes me feel gross. This drug has got to be taken off the market. A girl with no history of depression or mental/emotional issues suddenly having suicidal thoughts for NO REASON?! That is not ok! Someone in the FDA needs to take notice. Oh wait, they're the FDA... ok it's hopeless. F 23 6 weeks
1X day		 10/25/2012
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 1  Pregnancy prevention Extreme mood swings, depression, anxiety and claustrophobia, heart palpitations, low potassium(never had this issue prior to depo), no sex drive, painful intercourse, lethargy, and fatigue Worst experience of my life. Depo has changed me into a hateful psychotic bitch. I'm not myself. I used to be happy!! I can't stand to be around my fiancé and his touch literally repulses me which was absolutely not the case up until receiving this shot. I don't want to be around people because my patience is gone. I'm always anxious and I cry almost everyday for no reason. I've begun having panic attacks and heart palpitations randomly. This stuff is poison and I wouldn't wish this experience on my worst enemy. F 28 6 weeks
 5/30/2016
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 4  birth control Weight gain and sex drive decreased F 18 7 weeks
40 mgs		 5/16/2012
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 2  to gain weight i had 2 weeks of bleeeding and then some spotting. the only reason why i went on it was to gain weight and i havent gain anything which really sucks because i heard all these stories of weight gain on it. it doesnt look like im going to gain anything. F 17 7 weeks
 11/16/2004
 1  pregnancy prevention 7 weeks of non-stop spotting (and still going), weight gain, mood swings, loss of sex drive I have not stopped spotting since the day of the injection. Beacuse of this, or possibly as another sdie effect I was not warned about, I have lost all interest in sex. I have also gained about 5 lbs in 2 months with no change in my diet. I cry all the time and my boyfriend is understandably getting frustrated. I went on this to stop my periods and have a safer more spontaneous sex life, but instead I've been bleeding for almost two months and am not having any sex. Do not take this medication! Nothing is worth the havoc it wreaks on your body. F 23 7 weeks
 8/7/2008
 1  seemed easy and simple no weight change, normal sex drive, but my moodiness is out of control. I cry every day, several times a day. Anything that can touch my emotions can make me cry. This has caused major problems with my boyfriend because we fight all the time now, I'm always nagging at him for something and end up crying and making him feel terrible. I have not been myself since the day after my doctor gave me the shot. That say I cried for three hours straight because of some little thing and had to leave work because I could not stop. Since then it's been a regular thing for me to burst into tears at any given moment. My boyfriend and I had a wonderful, healthy relationship and now we fight all the time. I'm not taking another shot EVER F 25 7 weeks
 9/13/2005
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 1  prevent pregnancy I am a total nutjob. I wanted to have another child and didn't want to go back on the iud. So I opted for depo. I have back pain to the point that I can barely move and it's not just related to motion. I can be dead asleep and wake up with such a spasm and shooting pain it takes my breath away. I hate everyone and on the verge of a divorce because I am so angry all the time. I am not a violent person but now I find myself wanting to smash things, yelling and screaming all the time. Having fits of rage that actually scare me. Not to mention the depression. It's the worst, I don't want anything to do with anyone I cry for no reason nothing makes me happy and when I do become happy I cry even more because I feel so guilty for being so angry all the time and that puts me back into another depressive fit. I was diagnosed with uterine fibroids which the doc is pretty sure that I am seeing due to the shot. I feel totally out of control and am miserable. I got the 3 month shot and am 7 weeks i It may seem like a great thing but really check into this. I am scared what the residual side effects may be for me. And how long it will take to get out of my system, also not to mention the fibroids I now have because of taking it and if they will go away or get worse. I can't believe this is still on the market. F 31 7 weeks
? 1X O		 2/6/2012
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 1  Birth control Anxiety, hot flashes, period for 3 weeks so far, constantly paranoid, weight loss, fatigue, abnormal sleeping habits I took the shot for the first time Sept 18th I've been on the pill before and the first time I was on the pill it was ortho cyclen..well i go back to my doctor and she asks me if I've gained weight or was crying a lot and I had been so she switched me to a lower dose and said the pill would do that sometimes...well the shot was fine at first then about 20 days after I started getting nervous..over everything..I work in the lab so I constantly worry that I'm going to get exposed to hepatits...I accidentally touched my eyelash and started crying...I cry for no reason sometimes. I sleep 3 hours wake up then stay up..I've lost 15lbs from the stress. I'm scared to death constantly..I'm nervous all the time..My boyfriend is about to lose it from dealing with me..I went to my gyno and he said the hormones won't do that ..He said it was all in my head because I knew the hormones were there.. he gave me nerve pills to help with anxiety and sent me to another doctor for followup..If it's not t F 23 7 weeks
 11/4/2008
 1  To prepare for having the essure. Non stop bleeding, gushing. 7 weeks since I got this shot and haven't stopped. I am hungry, mood swinging irritated. I got it to prepare for a sterilization procedure at the suggestion of the nurse so they could make sure I wouldn't be pregnant on my appointment date. I'm also supposed to get another one after procedure until they're sure that it took. Not at this point. This is good example of why I want to get off the hormonal bc. F 34 7 weeks
150		 5/13/2014
 3  Prevent pregnancy Fatigue Headaches Loss of Libido Oily Skin Irregular and Frequent Bleeding Weight Loss F 21 8 weeks
1X AN		 4/27/2015
 1  Birth Control Loss of sex drive, hair loss, dramatic weight fluctuations, strange moods, anger at my partner, constant vaginal blood flow, heavy periods, severe period cramps, back ache, dry skin, passing enormous blood clots the size of a small fist, anxiety. I have had a successful run on the pill (triphasil) for about twenty years. My sex life is very active and experimental and I found the pill perfect for my sexual lifestyle. I went off it because I have a history of heart disease in my family (though I am very healthy) and because I decided on a period of abstinance after a tricky breakup. I started dating a man a few months ago, and we decided to take steps to have unprotected sex. I was recommended the Depo Provera shot by my (male) doctor even though I later found out that it is just as dangerous for people with heart disease in the family. (Same doctor wouldn't give me the pill, but would administer Depo) I was sick right away, but put it down to adjustments etc - bad period cramps etc - but at 7 weeks my sex drive completely fell away and that has never happened to me in my life before. I was horrified and it had a terrible effect on my relationship because I assumed it was our problem, not a chemical one. I will never, ever touch this shot again. It is used to castrate sex offenders and it is outdated medical research that imagines this doesn't affect women. At 8 weeks my side effects have not subsided. My partner is being patient but I am terribly upset about this and feel that something of great value has been stolen from me. F 48 8 weeks
1X AN		 4/2/2016
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 1  heavy bleeding Severe nausea and vomiting, shakes, chills, panic attacks, sweating, elevated liver enzymes,rash and itchiness, dizziness, continued and prolonged bleeding I would never ever reccommend this drug to anyone. I have now talked to 6 people that have had similar or worse reactions than mine. How is this drug even legal? F 44 8 weeks
1X day		 4/21/2014
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 2  To prevent pregnancy Acne. Weight gain. Irregular vaginal bleeding. Tendon/ligament pain. I was on estrogen/progestin contraception off and on in my late teens and early twenties, with few side-effects. I recently had a child and my ob/gyn and I decided a progestin-only form of birth control was right for me because I am currently nursing. Within a couple of days of the shot, I developed acne. Not typical teenager, oily-skin acne, but the cystic, deep-tissue variety. No exfoliating or scrubbing can solve my problem. I began having my period almost constantly. I would have a period for 7 days and then have a few days off, and then it would start up again. I had tendon/ligament pain in some of my joints, during pregnancy, which I attributed to elevated estrogen/progesterone during pregnancy. I assume the elevated progestin (synthetic progesterone of Depo) has a similar effect. I am breastfeeding exclusively, which should allow a moderate weight loss (1-2 lbs/week) with a healthy diet (which I eat). My weight hasn't budged since going on Depo 12 weeks post-partum. F 28 9 weeks
 4/26/2005
 2  Birth Control severe back pain, breast thickening/lumpiness/extreme tenderness and pain, mood swings, headaches, fatigue, extreme and nonstop spotting/bleeding for the first 3-5 weeks, multiple yeast infections and vaginal discomfort, vaginal tenderness/discomfort/pain after intercourse, decreased sex drive I have only been on this method of birth control for about 2 months, has anyone noticed that their side effects decrease with continued use or do they continue even after multiple shots? Has anyone found another birth control that works for them without many extreme side effects such as these? F 19 9 weeks
 4/27/2007
 1  birth control increase in appetite, mood swings, irregular bleeding, decreased interest in sex. Like others, I have had the WORST mood swings imaginable. My sex drive is practically non-existant, and although it says that your periods may stop all together, it is like mine has never stopped. Like someone else said, a big reason why this works for birth control is because you either don't want it, can't have it (because of spotting), or are far too moody for your boyfriend/husband to want to have anything to do with you. F 21 9 weeks
 9/14/2009
 1  Birth Control Weight gain, moody, easily irritated, bloated, and an overall feeling of being pregnant and I am not. This medication has been horrible from the very first week. I immediately began my cycle and bled for 6 weeks with only a day or two in which I wasn't bleeding heavily with occasional "chunks of tissue." I continue to spot almost daily. I am so bloated I can no longer fit into most of my clothes. My breasts are huge and feel like they weigh 3 pounds each - my bra size was a small "C" prior to this injection; but now I think I must be a "D" or bigger as I'm busting out of my bras. I am constantly hungry and have gained 6 pounds over the past 9 weeks. Prior to this medication I was fun, happy, and easy going. Now however I am easily irritated and will go off for no apparent reason. I will NOT be taking an additional injection and i am emailing all of my friends to avoid this medication. THIS IS THE WORST MEDICATION I HAVE EVER PUT INTO MY SYSTEM AND I REGRET THE DAY I MADE THE UNINFORMED DECISION TO DO IT. F 41 9 weeks
 9/1/2009

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