DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  safe for breast-feeding Please stop this medication. Only side effect while on was weight gain. It is when you stop the true side effects come out. Hormonal imbalance(high testerone and high cortisol levels and normal to low estrogen, infertility, became polycystic, hair loss, joint pain, depression and inability to loose weight, insominia, insulin resistant. I was 25 when introduced to depo. I just had my son (who I got pregnant with while on regular birth control) and they ask if I wanted to breast feeding then told me the only thing I could take was depo. So being young and it new I agreed. Loved it at first no periods, but had weight gain I thought no big deal. My husband was mad told me not to take it. Should of listened. I stopped taking at 27 to try and get pregnant. I couldnt get a period so doc put me on birth control to start my periods finally a period after a year. Then trying to get pregnant. I did get pregnant at 30 miscarried told just a percentage. Then got pregnant at 31 miscarried. Finally doc start to investigate. Relized I had PCOS and body did not produce enough progesterone when pregnant to hold baby. I am now 35 still have not been able to get pregnant, tried fertility pills nothing is working. Periods still not back to my normal 28 cycle. It has been 8yrs and hormonally I am still a wreck. Went to new MD and she ran F 35 2 days
9/10/2007
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 1  I have stage 4 endomitriosis Side Effects: Extreme mood swings, (i have never been so angry, irritable, personality change and depression) Knees aching, cramping, terrible periods, Discharge (yellowish color and alot of it..its horrible and embarressing!) Vaginal Dryness, Hurts having Sex, Trouble remembering things, Insomnia, Fatigue, Energy Loss, Increased appetite, Weight Gain.... Just way to many side effects for me. I have had 3 surgeries within the past 2 years due to endomitriosis and ovarian cysts. They put me on Lupron which I loved. Took me off of it because of the bone loss...I work out 4 days a wk and eat healthy. Dr. decided that depo-provera...informed me of some side effects. I do not like this drug. I have felt like crape and wouldnt wish this on anyone. F 35 2 days
1/26/2009
 1  CONTRACEPTION I gained alot of weight and I feel that it did something to my metabolism. My body hasn't been the same since I took it and I know that even though I haven't taken it in quite sometime I feel it left a irreversible side effect with me. BEWARE!!! I KNOW ALOT OF PEOPLE THAT FEEL THIS WAY ABOUT THIS DRUG. THE LASTING EFFECTS THAT IT HAS ON YOUR BODY ISN'T WORTH IT IN MY BOOK. F 40 2 days
12/8/2004
 5  irregular/debilitating periods After the first two years w/ few side effects the shot was changed (injection location) to my upper thighs instead of butt. I have since experienced dimpling at the site which hasn't shown any sign of healing/going away in a year. All things concidered I've been extreemly pleased with this shot. I haven't felt an ounce of pain or seen a drop of blood in almost 2 1/2 years though it did take about 6 months to adjust. No weight gain. I do experience notable vaginal dryness but it hasn't affected my sex drive. I am concerned about the dimples in my legs however. My doctor has one other similar case but no one seems to be able to offer me any explanaition for the reaction or any geuss as to whether these are now permanant markings. I've had no reaction in the shoulder, butt, or abdomin. If theres any one out there who's noticed something similar and might have found a better answer than just changing the injection sight I would love to hear from you. F 23 3 days
8/27/2007
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 4  bc weight gain iv been using this in regards to bc for just about 3 years now. My mood has changed dramatically for the better. its easier to make a dr appt at the end of a 3 month window than it is to take a pill everyday-personally. I wouldnt rule out other forms of contraceptives however. I have gained a bit of weight these past few years. Not enough to have to go out and buy a new wardrobe but enough to want to hit the gym. Its deffinatly not for everyone. And each person getting this shot has their own reason. Dont be afraid to ask your dr questions. And most importantly dont be afraid to stop getting the shot if you no longer think its right for you. One thing i have noticed about getting this is that i feel sometimes obligated to continue with it. Just keep asking yourself- is this still something im interested in? F 19 3 days
10/11/2009
 4  very painful periods When I first started taking this, i was about 165-170 not very husky.. ive been on this for about 3 years and ive ballooned to a whopping 230 pounds. And on top of that I have a hernia. Doubt if the depo caused that but all this extra weight that im carrying around is hard to get rid of. I dont know. I dont recommend this to anyone but I am kinda satisfied because I havent had a period. I would like to switch but im not sure. F 23 3 days
1/16/2014
 4  Birth control just a little sleepy I have been readind some of the comments and wonder if most of the women on here were completely healthy or have any family illnesses that the shot could trigger. Because I am very healthy only allergy I have is penicllin. It is rare for me to get side affects from anything I take so it could just be your family history or your health. If I were to get mood swings I would not let it distroy my marriage or loose my boyfriend because you have to learn to control your anger we are adults here you dont have to say what pops into your head if you know its going to hurt the other person. Weight gain I believe there is no way you are stuck being 20 or 45 pounds if you dieting and excercising. It makes no sense you are either not keeping up with excercising or overeating. The only thing I am worried about is the bone lost so I wont be on the shot for more than 3 years. F 22 3 days
1X AN
6/11/2011
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 3  birth control I took the generic version of depo for three years until April of 2005. I experienced horrible acne across my back, shoulders, face & neck (I never had acne before). I took tetracycline to control the acne but it was only moderately effective. I also experienced eczema covering about 80% of my body. I'm prone to eczema anyway, so I feel it threw it into overdrive. It was so bad it kept me awake all night. I still have acne scars on my back. Its been nine months since I was on it; the eczema is SLOWLY starting to go away. The acne is GONE. It also decreased my sex drive and increased my appetite. I'm slowly losing weight (I gained 20 pounds and have lost about 4.) I tried to exercise to reduce the weight but the heat and sweat irritated my eczema to the point it burned like poison ivy. I LOVED the absence menstrual periods, but the side effects were intolerable. My husband has since had a vasectomy (may the gods bless him.) F 38 3 days
1/27/2007
 3  to stop my period during chemo MAJOR weight gain,(75 pounds in all) still get PMS, toenail fungus I read one ladies comment saying that you don't gain weight, get toe fungus, get PMS etc, and I'd like to say, SHE is insane! I am currently on chemo, and throw up from it on a regular basis, and still have gained 75 pounds! I also never had toenail fungus before going on the depo shot, and now I DO have toenail fungus, coincidence? I think not. Also, I still get MAJOR PMS even though I don't get my period. I am having a hysterectomy this summer, because the cancer has spread, and I can't WAIT to be off of the depo shot :) F 33 3 days
5/5/2006
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 3  birth control painfull sex, hair in places i dont want it and loss in places i do. lack of lubercation during sex,spotting, headaches,body pain and aches in back,shortness of breath, loss of energy,depression, and i gained 20 lbs. i have been on the depo for 3 years and i have never felt so bad in my whole life. But, IM NOT PREGNANT! thats the only good thing!!! 19 3 days
2/28/2005
 2  birth control/to gain weight with in the first year - great. now i hate it i never feel happy, i don't smile any more because i don't feel i have anything to smile about, and i always feel depressed and that something wrong is going to happen for no apparent reason,im always tired, trouble getting to sleep & NO SEX been 19yrs old with 3 children i thought the depo. was perfect for me, as it worked for my mom for 18 yrs although she had side affects for the last 2 yrs of having it. Now for me i hate it because i have horrible mood swings, pain in the bottom of my stomach, totally loss of sex drive, and loss of natural lubrication which only leeds to painful (rape like) sex. there have been times during love making that i have just lay there and cried until it was over, because been on the depo i hate sex. i am now coming off the drug after been on it for 3yrs and going back to the alternatve route of condoms - no major or horrible side affects from them!!! i wouldn't recommend this for any lady who still wants to feel like a lady F 22 3 days
7/29/2005
 2  Birth control Weight gain, headaches, body aches, severe mood swings, low sex drive I started getttig the shot when i was 17. It worked with noo side effeect for a year. I stopped getting the shot( broke up with my BF) I started it again when i was 21 it worked fine for a year but once I experienced my first anxiety attack right before my wedding I went totaly out of wack. I started gaining weight, crying uncontrolably, having horrible mirgaines that would lasdt for days, ot have weird shooting pains in my head. I had an MRI of my brain bc they were so often. I had no sex drive (being a newlywed this really upset my marriage) I stopped the shots in November 2010 and have not gotten my period yet. My doctor said that i might be three months after my last shot to get out of my system before I got my period. That was supposed to be February but nothing. Ive had alot of PMS symptoms off and on through out the entire time. The crying, severe moods swings, and really low sex drve have all kind of gone away but the migraines, fatigue, body aches still remain :( F 23 3 days
1X O
5/18/2011
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 1   im 19 have been on depo for the last 2months and can not stand the side effects that come with it. sure it stops you from getting preg but at the same time the side effects make you feel as if you are. i get really dizzy tired all the time moody and get bad anxiety which makes me think of sucidel thoughts i really feel like i am going crazy and hope it will where of soon i have a 20month lil boy and can not deal with these side effects working and looking after him. F 19 3 days
1X day
2/8/2010
 1  control my periods severe anxiety attacks, blurred vision, already gaining..moody my mom had gone this route because the pill made her a bitch from hell.. the pill wasnt working for me due to nausea.. so i switched.. its only been three days but last night i had a severe anxiety attack and stare3d being hysterical. scared my to death. also my boyfriend has noticed me being way moodier and also like an instant weight gain.. i got on it to avoid this.. three more months.. can i do it? anyway i thought i was alone but i see im not.. M 17 3 days
not sure 1X O
11/14/2010
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 1  birth control ive only been on it for 3 days and i hate it! i decided to take it because my doctor convinced me that it was best. i just had a little boy (c- section) 2 months ago and my doctor said my body needed time to heal. So Consequently i listened. now i regret it! im already experiencing severe mood swings and depression. i cant imagine what im going to be like when i start gaining wait. girls this is TERRIBLE never take it!!!! my doctor gave me a packet of all the different kinds of birth control so i could decide which was the best for me. i trusted that everything i needed to know about depo was in there. unfortionally i was wrong! i was never informed about the acne,depression,moodswings or "miscarriage" you can have after discontinuing use of depo. if i had known about all these terrible side effects i would have never decided to take this. F 20 3 days
10/26/2008
 1  prevent pregnancy major hairloss, cystic like acne, unwanted hair growth in areas it shouldn't, unexplained mood swings, a period that never stops, zero sex drive, vaginal dryness I only got the shot once and will never again. My period lasted straight for four months after I got the shot. And now when I do get my periods they last for 2 wks or more and it's a black or brown discharge...how embarrassing!! One thing is for sure is the effectiveness of this drug...how the hell can I get pregnant when I can't have sex cuz my gross period won't stop???? I would never ever recommend this form of birth control to anyone!! F 36 3 days
1/21/2007
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 1  birth control Severe anxiety depression mood swings paranoia muscle pain panic attacks F 29 3 days
9/30/2012
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 1  Birth control Weight gain increased cancer risk F 36 3 days
10/1/2012
 1  Easier than the pill I had bled almost constantly after the first month on it, i did not get my second dose in september, and up untill two weeks i bled off and on and had three different heavy periods before finally the bleeding/spotting ended. Also lumps in my breast, bad cramping. I would never get this shot again. F 3 days
11/29/2012
 1  contraceptive method Taken for 3 years - never had any STD'S, been tested every year & negative. Then, eptopic pregnancy, PID,then Infertility!! It sounds great. No pregnancy & of course the real reason women take this contraceptive..no period. In the long run, not so good. Definately not recommend taking this drug! F 26 3 days
7/24/2007

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