DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  horrible periods HORRIBLE!! I had very severe periods since getting my first period at age 11. From Heavy bleeding to cramping so intense feeling as though being "gutted with an ice pick" as well as painful cramping in my thighs. I had tried every form of birth control known to man growing up. After having my child and not wanting to have any more at that time I first tried the Depo shot. It really sounded like a dream come true for someone like me who has gone most their life in such pelvic pain due to my menstrual periods. I quickly learned just how wrong of a decision it was I had made for my self. I no longer felt like myself. My moods were unpredictable and yet so destructive. I always felt tired, never wanting to do the normal things I have always done. I had no motivation for much of anything at this point. Tossing the idea back and fourth wondering if it was due to depression which I had experienced before but yet this still felt very different than any depressing moods I had befo F 29 2 years
30 mg 1X M
12/13/2013
 3  Couldn't remember to take pill. I am currently on the shot. I am sexually active. I've been on the shot since April and all of a sudden I started having light spotting and very weird cravings! Is this normal? F 18 8 months
Unknown
12/10/2013
 1  To prevent pregnancy I would not recommend a female take this shot. I got on the Depo shot In Oct which was my first dose im due to get another shot in jan. Do you think im going back? ? NO! They dont tell you that this causes memory loss. For the last month I have really been forgetful like i barely remember what went on the day before. I knew something wasn't right with me. Like to the point I was lookin up early damentia in the 20s . Yea thats how bad its been. I Finally looked up depo shot and memory loss and what do you kno, smh other women have experienced this as well. I read something that said people who have taken depo vs ppl who havent have more of a chance in developing cognitive issues such as memory loss, attention span, and thinking.. Dont take this shot. F 22 2 months
12/9/2013
 1  Could not remember to take the pill Depo has been awful for me. At first I thought it was great - no periods. But after the first 2 months I noticed significant weight gain. I have gained 6 kilos whilst on depo and that's when I've been exercising with a PT daily and eating very healthy. I am also always tired. No matter how much sleep I've had and I'm severely depressed. F 22 2 times
12/4/2013
 1  My period is horrible Since I have been on depo I've bled.. in January it would make 6 months of bleeding with this blood come a stanky brown discharge it makes me have a odor no matter how much I take a shower or shave ..also I always feel like I have to throw up , I have chest pain and my vigina be in pain , I'm really lazy , my face is breaking out I just don't know what to do it ruining me right now please help me ..I think it gave me a uti or interstitial cystitis F 16 4 months
Idk
12/1/2013
Email
 1  to prevent pregnancy NEVER and I repeat NEVER let this shot near you. Ever since taking it I have heart problems and aniexty through the roof I wake up shakey everyday, im always a nervous reck. The first time I received it was August 13th 2013 and I experienced BAD BAD dizziness couldn't even drive. The worst is the heart problems I developed mitral valve prolapse, and I NEVER EVER had heart problems, I went through my whole pregnancy amd before that with no heart problems, I take one shot and it ruined my life I no longer can do the things i once did , I feel like im a dead body. F 24 1 days
1
11/11/2013
Email
 1  pregnancy prevention Very irregular periods that would last up to three weeks, mood swings, lack of sex drive F 24 1 years
11/5/2013
 3  Contraception i wish i read all the reviews on this page before i got it, a friend recommended it to me claiming it to be amazing. First 2 months we're fine, slight weight gain and a few extra spots, nothing too bad. However the 3rd month i bled off and on throughout, ruined my sex life completely, i found myself getting aggravated over the simplest things, constant headaches, unbearable bellyaches, it was horrible. i've recently been put on the pill and hopefully this all improves (i started it 2 days ago) i would not recommend the DEPO to anybody, messes with your body so much & now i'm told my fertility could take up to 18 months to return! Avoid it. F 18 3 months
1X AN
10/29/2013
Email
 1  just had a baby I have not stopped bleeding since the day i got the shot. Alot of the time it's accompanied by a foul smelling brown discharge i cannot get rid of. My hair is falling out in clumps, I've probably lost about half of my hair. Depression and awful anxiety about everything. Extreme irritability. Absolutely no sex drive. I gained 15 lbs within the first month after the shot. I feel I'm always starving. I have not been able to get a good quality of sleep. My entire face has dried up and is cracking, and i have huge painful pimples all over the place, which i cannot do anything about. I was due for my second shot about a week ago, but there is no way i could do that to myself again. If my Dr. had actually told me of the side effects of the depo shot i would've never even thought about getting it. This drug should be made illegal. F 18 3 months
10/22/2013
Email
 1  birth control Coming off depo hard pelvic area like in pregnancy nipple tenderness dry no sex drive depression mood swings no period last shot was due June 7 2013 F 34 5 years
30 mg
10/22/2013
 5  Birth Control Weight gain of at least 20 pounds, however I have no period or period-like symptoms, my sex drive is completely fine, and I have no health problems to speak of. F 18 4 years
1X AN
10/20/2013
Email
 1  birth control Major weight gain! 25 lbs in 6 months!! I am hungry all the time, have had very low energy, mood swings, depression etc. It has prevented pregnancy, but at a cost of no sex drive, and due to the fact that 2 weeks after my last shot, I have been spotting for a month, and now I've been bleeding light-to moderate while experiencing other period symptoms for 3 weeks! Therefore, not been able to have sex for almost 2 months now. No wonder it has such high % of effectiveness!! This drug has completely ruined my sex life, including my self esteem (weight gain). I am very grateful that I have a very understanding, considerate husband!!! Who has since had a vasectomy, because this drug is SO TERRIBLE!!! F 26 6 months
10/9/2013
 1  Period regulation Depo has made me feel mentally insane I would not recommend this to anyone who has a family history of depression because it will just amplify your feelings of depression. I first got my depo shot in the end of June everything was okay for the first couple weeks I was spotting bad then all of a sudden I have terrible mood swings and I always feel bloated and gross. Then comes the depression and violent negative thoughts of hurting myself or others. In my mind I know I've never thought like this my entire life or this depressed. I've recently had panic attacks when I start getting really depressed and having negative thoughts feeling like I'm out of control. It's October now my 3 months have been up but I can still feel the depression slightly and some random negative thoughts. Also agreeing with other reviews zero sex drive in general. Very terrible anxiety..! I've recently felt like crying for no reason and felt sad for NO apparent reason I don't know if this is depo withdrawals kicking in or what but I hope this evil drug gets out of my body soon. And I would never recommend this to anyone. Stay away from this drug. It will make you want to kill yourself or hurt others. F 22 3 months
30mg
10/3/2013
 1  just had my second baby extreme moodiness, irrational thoughts, severe depression, severe anger, suicidal thoughts, hair loss, weight gain. After I received the shot I became very depressed and moody towards my husband and my 2 yr old daughter. I just snapped over the littlest, dumbest things and I couldn't figure out what it was. I thought it was bc I was stressed about caring for 2 kids full time and bc I'm breastfeeding and that made me hormonal. Now after reading all the other reviews I know it has to be the shot. My hair is falling out in clumps and I'm definitely not going to get another shot. F 24 3 months
9/28/2013
Email
 1   This shot has ruined me, I have terrible anxiety since the day after the second shot. All sorts of GI issues, hair loss, itchiness, depression,. I really feel like I was losing my mind. I felt like every pain I felt meant I had cancer and was going to die. I had can scans, blood work, upper GI series and nothing is wrong with me yet I'm in this total panic all the time. It's comforting to read others experiences as I feel like I'm not crazy...... I got my tubes tied and my gyno have me a D&c and that helped for about 3 weeks, I was symptom free....... 6 more weeks and I will be die for another shot that I won't be getting!!!!!! Hopefully relief in sight...... F 36 4 days
9/25/2013
 5  Uncontrolled bleeding No menstrual cycle, EVER! Irritability, dryness, stopped the shot to explore other options though I was reluctant because I love it. 5 years is a lot for the shot I guess.... Now that I am being weaned off the shot I am extremely crazy horny all the time! 30 5 years
9/24/2013
 1  Previously had a blood clot Hair loss, itchy breast and 'down there', absolutely no sex drive/didn't want to be touched at all, severe depression and worst temper I have ever seen, can not lose weight, awful stomach pains, dizziness, headaches, anxiety. F 29 9 months
9/24/2013
Email
 1  Heavy periods, birth control Loss of sex drive, weight gain, depression, mood swings, headaches. Also I was diagnosed with interstitial cystitis, a disease where you have Utis everyday. And this disease has completely ruined my life. I'm 20 years old and had to quit having a social life, work, and school. I spend everyday sitting on the toilet and crying or in a hospital bed. I also got diagnosed with IBS which causes horrible stomach pain. I have a 3 year old and depo has really effected my ability to care for her. Most days I don't even wanna live I'm in so much pain. Not to mention all my hair fell out. I not leave my house anymore cause I have bald spots. I hate myself and how I look I feel so ugly. I don't know how this stuff is on the market it's horrible. Please no one take this. Everyday I'm miserable depo has ruined my life F 20 3 months
15mg
9/22/2013
Email
 1  for pelvic congestive syndrome Complete Iibido Loss, weight Gain, urinary tract infections, pelvic infections, depression, mood swings, gasterontestinal upset, bad acne, hypothyroidism. I will never EVER use this poison again. Once I got off I experienced short term withdrawls after stopping in march of 2013 and still waiting for a period and body to come back to normal. I hated being on it and myself and my husband didn't like the person I was while on it and the health complaints. I do NOT reccomend this B/c. F 30 1 years
9/17/2013
Email
 1  pelvic congestive syndrome Complete loss of libido, weight gain, severe anxiety attacks, depression, urinary infections, pelvic infections, severe mood swing, digestive upset, constipation, nausea, headaches, developed hypothyroidism just while on it, weakened immune system, urinary irritation constantly, withdraws, upon getting off it, lack of menstruation even after stopping. I would recommend that NO ONE use this as a form of b/c method. It has ruined my life and cause so many health issues. while being on it I have never had so many health issues that sent me to the doctor back and forth and to the emergency room. My tubes are tied so I only used it as a method to calm my pelvic congestive syndrome and wished that the pcs was the only issue and rather had dealt with only that instead of all the issues after taking the shot .The withdraws were awful after stopping the drug. And I developed a hypothyroidism while on it then it went back to normal after going off shot. my last shot was suppose to be march of 2013 but I refused it. since then im still waiting for my period to return so that my body be restored back to its normal self. I HATE this b/c and will NEVER use it again. It may work for some but its not for me. Its poison!!! NOT a good drug! F 30 1 years
4 shots 1X O
9/17/2013
Email

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