DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Birth control Fatigue, bloating, weight gain, migranes, nausia, aches and pains, emtiotional/mood swings, abdominal pain (being tested soon for infertility etc) dizzyness, loss of labido, vaginal dryness, hair loss. Alot of these side effects have only started in the last 6-12 months. The depo has been deceptive.....to start with it was a godsend as my periods completely stopped and the 3 monthly jabs were great, the high sucess rate grew my trust and made me rely on the depo. Now after 5 years i am stopping the depo....and DO NOT reccomend it to anyone who doesnt already know ALL side effects! F 20 4 years
1/11/2012
 3  because i forgot to take my pills at first it was great..yea spotting but i didnt care. nothing to worry about. but now after 2 and a half years i gained 15 pounds quickly i have headaches everyyyyyyday! no sex drive. low mood. mood swings. depression? F 20 2 years
11/2/2007
 3  don't want to get pregnant,convenience EXTREME vaginal dryness...painful sex as a result, discharge, stomach pain, slight mood changes, REALLY BAD INSOMNIA I didn't realize until I found this site where the vaginal dryness came from. It's awful and nearly destroyed my sex life with the guy I am seeing. I'm 20, I don't want to use lube! Sex was painful, almost with a stinging. Strange discharge and itching and I have been tested twice, with clean results, so it is depo's doing. I love the freedom of not worrying, but if I start gaining weight there is no way I will take my second shot. Also one thing I wasn't expecting, because I had been on an estrogen based birth control pill before, once I got the shot, my breasts have actually gotten SMALLER...which at an A already is pretty bad. I look like I'm 13. F 20 1 times
1/24/2009
 3  Regulate Menstrual Cycle & BC (-) NO sex drive, painful sex, dry as the gobi desert, the mother of all discharge, depression, anxiety, back aches, mood swings, and what is worse: a complete lack of confidence (+) No period for 3 years, no pregnancy I have been on depo for going on 4 years. Before the shot I enjoyed having sex (although I was WAY TOO YOUNG) I still enjoyed it. I don't remember the last time I really could do it without problems. It is very painful when I do want it, and for the most part I complain to my boyfriend when he touches me because I am not into it. (And it is not HIS fault) I've had bouts with depression since 2002 (6 months after I began depo) and severe anxiety in the past 2 years. I have SEVERE back ache and pain in my joints. I dont know if this is to do with the shot but recently I've been thinking so. It started after I began the shot. I have a total lack of confidence due to my decreased sex drive. The shot has made me feel unfeminine and totally not sexy. I feel like a failure in the sex department. The only reason I give it a 3 is because I have had no babies and no period. F 20 4 years
5/10/2005
 3  birth control panic attacks, no weight gain I believe this drug has caused panic attacks. I have had a history of panic attacks but they only occurred in highly stressful situations. But now I have panic attacks almost every single day even in situations that are normally not stressful! It has effected my life enough where I had to start taking Effexor. F 20 2 years
4/12/2007
 3  Prevent pregnancy Missing a shot caused me to have a period for atleast 2-3 months straight. Although I dont get periods anymore and dont miss my shots, i still get cramps and sometimes spot very lightly. Lately I have had weird pain in my abdomin. Not sure if thats the depo. F 20 5 days
1/28/2005
 3  birth control wanted no pills hair loss,weight gain 5-15 per shot, moodswings, no sex drive, headaches, dizziness, painful cramps in lower abdomin. Good for not getting pregnant but side affects not worth using this drug.I have gained lots of weight (30lb)and when i lose some the next shot brings back all i lost and more. Do not use this drug, it caused osteoproses. Did you know they use this drug to lower the libido of sex offenders? IT is illegal in many countries and it should be here too. I got my last shot in july and i am never going back, i rather have another baby!! F 20 13 months
8/18/2008
 3  to prevent pregnancy no sex drive whatsoever, incredibly moody, and tired ALL THE TIME. this is the first month of my second shot....so ive been taking depo for about 4-5 months now. F 20
5/21/2009
 3  Birth Control and Cramps Weight gain, I stopped getting a menstral cycle, barely any acne, no headaches, no pms I was on Depo-Provera for 2 years. I finally decided to get off of the injection because I gained 40 pounds in one year without changing any of my eating habits. I hated the injection at first because I still got my period for about 4 months after my first injection. The bleeding would last for three weeks. I did consult a doctor who said that my uterus was just getting rid of the build up on the wall of the uterus. Then my period completely went away. I loved it. Plus I got less acne and felt one hundred percent. I did however stop getting the injections because of my upcoming wedding and wanting to lose the weight I gained. F 20 2 years
7/14/2009
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 3  Prevent Pregnancy I've been on Depo-Provera for a little over a month now and I was kind of scared and cautious about what I was doing with my body but I decided to get the shot anyway. I got the pill about a day or two about before I was due to have my period. After getting the shot, I never got my period (even to this day). The shot is good for what it's supposed to do (prevent pregnancy) but it has many side effects. About a week after getting the shot, I experienced mood swings and I would get upset and cry over everything. I was an emotional wreck. I still get this every once in a while. I've also experienced hot flashes. I'm only 20 and still too young to be experiencing hot flashes. I would start sweating and getting really hot to the point wear I needed to sit down because I felt that I was going to pass out. I also just started spotting and it's not any normal spotting to wear you would have with a regular period, I would spot dark brown stuff. It was really gross. I'm getting abdominal pain (which isn't as bad as if I would have a normal period), I get occassional headaches and I've been gaining weight really quick. I would always be hungry and have a taste for different foods. I think this would be my first and last shot of Depo-Provera. I would not recommend this to people unless you've fully read up on all the effects and know what your getting yourself into. F 20 1 months
30MG
4/6/2014
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 3  To prevent pregnancy My period has completely stopped since I began the shot (not complaining) but I have headaches, back aches, thinning of my hair, knots in my neck, acne and I have no sex drive. I have 1 child and the shot has prevented from getting pregnant for 2 1/2 almost three years but the side effects are terrible. It is bad for you bones, skin . The only positive thing is that i dont have a period but i don't recommend it to anyone. F 20 2 years
2/4/2016
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 3  Contraceptive Depression, weakness, tiredness, low sex drive, headaches feel like migraines, nausea, high appetite. The first time I took depo provera I didn't have any of these symptoms. I got the shot about a week ago, and I've been feeling shitty for two days now. My emotions are all over the place. I wake up feeling weak with a headache. It gets the job done, however the side effects are the worst. Switching my method after this is done. F 20 10 days
12/7/2016
 2  Pregnancy prevention Loss of period, vaginal dryness, muscle pain (only a few days after getting the shot), and painful sex After being on the shot after a year I am going to switch to another method because the vaginal dryness and painful intercourse ruined my sex life. F 20 1 years
30 MG
5/23/2020
 2  Prevention of Pregnancy It was too hard to remember to take the pill, so I opted for something I didn't have to take consistently. I was so excited to get this shot, the first two days or so were okay, except my attitude was very nasty and I found myself very easily angered. I actually got the shot the first day of my period, so once I got off my period there was only minimal spotting. Less than a week, I started feeling short of breath and one day it had gotten so bad I had gone to the ER. They told me I had a blood clot in my lung. Now, I have a history of blood clots and I informed my nurse. She insisted Depo Provera would actually thin my blood, and be less of a risk than the pill. Bullshit. F 20 1 weeks
4/1/2017
Email
 2  bad periods bad cramps weight gain (nearly forty pounds) acne mood, swings to the extent of being diagnosed bipolar, migraines well it stopped the periods for the most part i never new i shouldnt take it for more than two years goof thing two years is the next shot.but i always have pimples never stable in my mood. and always in pain of some form or another F 20 2 years
7/20/2009
 2  Birth control Weight loss and minor issues I will cover in comments. Very negative change in vaginal discharge and bleeding: thicker, drier, and everything started to turn brown or black! I came off of Depo in January ('09). It never did what it was supposed to because after taking it I spotted (sometimes bled) almost every day and any discharge was brown or black and tacky. After about 2 months off Depo I noticed a definite change. Improved consistency and wetness of discharge, and my sex drive improved. I have never been regular and though my periods have always been super heavy, I never experienced anything else. But since starting (and stopping) Depo, I have experienced small headaches on a regular basis, cramping (sometimes severe) and I bloat and/or experience gas pain almost daily. F 20 9 months
10/29/2009
Email
 2  prevent pregnancy i started the shot late july 2009 after terminating a pregnancy. since then i have only gained 4 pounds, no acne, sex drive hasn't changed but it seems like since i have been on the shot i spot everyday. about a week ago i got my first period since being on the shot and its heavier than my regular period has ever been. i've passed 3 huge blood clots in a matter of 3 days [which scared the life out of me] and its lasting longer than usual. honestly if i would've known that i'd be bleeding the whole summer and some i'd have rather not taken any bc. F 20 45 days
9/4/2009
 2  not become pregnant nausea,headaches,loss in sex drive,major mood swings, gained weight,being unhappy for no reason, depressed.hot flashes, and being a time bomb. at first it seems all cool then its like your experiencing so many symptoms.who would wanna feel depressed like half the time.not recommended if your in a relationship or have any social gatherings. its just not worth it. F 20 2 years
8/4/2008
 2  I kept forgetting to take pills tired all the time...nauseated all day every day... mood swings.... bloating headaches... also light headed...n im not sure but feels like i gained some weight I did miss my period this month which i like because im not cramping but i hate the side effects im having they are horrible F 20 1 months
7/26/2008
 2  Birth Control Weight Gain 35+ ,sleeplessness, headaches, depression I was on depo for 7 months and gained 35 pounds.I cannot stop eating I am so hungry all the time now.Its been 7 months that ive been off it and im still gaining. F 20 7 months
1/15/2005
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