DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  birth control weight gain, painful sex, no sex drive, dryness during sex, spotting, three month long period after stopping the shot this was the worst thing i ever did to myself, i got the shot so i could have sex and then it kept me from being able to do it at all. its just not worth it. i was only on the shot 6 months, and its almost 3 months later and the side effects are still occuring F 19 6 months
12/22/2004
 1  Heavy,painful periods,contraception Anxiety/paranoia/panic attacks, lethargy, depression, hopelessness, became withdrawn, 10-15 lb. weight gain, increased hunger, strange food cravings, inability to lose weight, body aches, night sweats, dehydration, vaginal dryness, irritability, uncharacteristic mood swings,lactation- YES LACTATION, periods did not go away completely and after a year became prolonged and painful, mental cloudiness, blurred vision, osteopenia, NEAR COMPLETE LOSS OF SEX DRIVE, painful sex, crying for no reason, prolonged bleeding, passing blood clots and stringy menstuation, fleshy discharge. Besides not getting pregnant after sex, I cannot think of a single good thing about Depo. I am 19 years old and receieved shots for a little over a year. I am now a completely different person. It is hard to say whether what I was experiencing was genetic or from Depo.. but I had once been a thin, out-going, energetic, social butterfly with a great body.. that was completely and utterly destroyed by depo. My cravings for food became unsatiable. My mood swings are still uncontrollable and I won't feel better until I bawl my eyes out. My stress level has increased ten-fold. Not only did I lose 85 percent of my sex drive, but it only returned an aditional 20 percent 6 months after I stopped. MY BODY HURTS. I now have osteopenia. I have endometreoisis.. which I probably had all along, but depo hardly helped at all and it is NOT WORTH IT. My breast size went from a D which I could hardly stand (on my 115 lbs fram) and now I'm an intolerable, unbearable, embarrassing DD-DDD,(I starte F 19 1.25 years
4/19/2007
 1  birth control; stop periods Severe acne (that I'd never had), vaginal dryness and itching, decreased sex drive, severe depression, anxiety, weight loss DO NOT TAKE DEPO PROVERA. If you notice, the majority of people with good things to say about this drug are still currently taking it at the moment. I was once like them too. When I first got on depo provera I lost my periods almost immediately and was EXCITED. I am a very petite girl so I was ok with the idea of gaining 5 to 10 lbs. This backfired, because i LOST 14 lbs. everyone thought i was anorexic- my appetite diminished and I was no longer eating like i use to. This alerted my mother, but i told her that everything else was fine and I didn't want my period. I stayed on it for 2 years and January of this year(2005) was my last shot. About 4 or 5 months afterward my period returned and that is when ALL HELL BROKE LOSE. My skin completely erupted in Severe acne all over my face, chest, back, and even my butt! I've never had these problems before; I use to be a model and be very outgoing with lots of friends. I'm none of those things anymore. I am depressed and cry everyday and have F 19 2 years
10/9/2005
 1  I took it as a birth control method I did not have a period which will take a toll on you after awhile,I got migraines,I gained 20 pounds,lost all interest in sex,and when i did decide to have sex it was extremely painful.I kept getting repetitive sinus and yeast infections. These are side effects I am going through now but there is a list of long term effects i could expirience down the road. I wouldn't recomend it for anybody. There are some pluses with getting the shot, but it''s really not worth it compared to all the side effects and health dangers that go hand in hand with it. F 19 1 years
7/1/2005
 1  Birth Control Non- Stop Bleeding, Mood Swing, Weight gain, Cramps I took my first shot on October 22nd 2012, i never got my period in the month of October but i just felt cramps. In the month of Nov 11th 2012, i started bleeding lightly non stop for every day also i started getting mood swings and i was not able to have sex due to the bleeding. All through Dec 2012 i still was bleeding non stop. My last month which is Jan 2012, the shot is wearing off and the bleeding reduced but haven't stopped yet. I would not recommend anyone to take this. F 19 3 months
30 1X day
1/21/2013
Email
 1  birth control I hated it...I never got my period ..and now that I'm off of it I got cysts in my ovaries and unable to keep a baby full term!!! F 19 3 years
30
2/4/2013
Email
 1  birth control Complete loss of sex drive, and lubrication. Painfull sex to the point of almost crying at times. headaches, weight gain only about 5 pounds tho. Hair loss that made me very self concious and afraid to style my hair for fear of loosing more. i bled for 4 months straight after i had just stopped bleeding from having my daughter im glad i switched to ovcon ive only been on it a few days but my headaches have subsided and hopefully my sex drive will come back, my husband is not to happy with the depo shot either. i have to say i wouldnt tell anyone to take the shot. it may be nice to not get ur period but honestly, id prefer to have painless sex and no hair loss with my period than to have no period and in pain and constant wonder if im pregnant. F 19 5 months
12/9/2005
 1  endometriosis I lost about 10 lbs in the first year and a half, then I gained 60 lbs in 9 months. I had SEVERE headaches and backaches, my hair fell out in big chunks, SEVERE breast tenderness, depression, mood swings, always thirsty, tiredness, lumps in my back and breasts. I would not recommend this drug to ANY one for ANY reason. I've been off for about three months and most of my side effects have gone away. F 19 2.5 years
2/6/2006
 1  birth control heavy spotting, weight gain, dizziness, nausea i was not told in the doctors office that depo provera could cause bone thinning, and that when i decided to try to concieve, it could take up to 12 months for the depo to completely leave my body before i could conceive. i DO NOT like this shot. i was due for my second one in december, and did not go in. i bled from the end of november to the beginning of january, stopped and now the bleeding is back. i only had one shot, but it did last 3 months as it should have. F 19 3 months
2/5/2007
Email
 1  Birth-Control/Stop Irregular Period I have taken the Depo shot for 15 months now, i was not made aware of all of the side effects. However, i was told about the mood swings and weight gain after i had my 1st baby. After one shot i noticed alot of my hair falling out, i assumed it was from the surgery or from having a baby, kept taking the shot and now 15 months later all my hair behind my neck is broken off to about 2 inches long. my hair was long, way past my shoulders. i never wear my hair up so i never noticed it was this bad, currently i have about half of my hair and have had to chop it off above my shoulders to make it look right, i have a gap close to my right shoulder where almost all my hair is broken off. I am severely depressed now because of my hair and my doctor swears its not the shot, dr.s do not listen i have tried everything to help my hair its not stress, not my shampoo, i take vitamins, and i am healthy. this is a horrible shot. I am 19yrs old and have no hair. I DO NOT RECOMMEND THIS SHOT TO ANYONE UNLESS YOU ARE ALREADY BALD. YOUR DOCTOR SHOULD TELL YOU ALL THE SIDE EFFECTS OF A DRUG, I MEAN AFTER ALL HAIR IS WHAT DEFINES A WOMAN FROM A MAN! F 19 15 months
7/21/2008
 1  Birth Control Severe memory loss and confusion, migraines, back pain, severe itching, total loss of sex drive, nervousness, shortness of breath, painful intercourse, blurry vision, increased liver function and many more... This injection has ruined my life. I thought I had something seriously wrong with me as my liver function was 636 (suppose to be between 1-50), my spleen was enlarged, my relationship is nearly ruined and I'm still trying to get over this pathetic excuse for contraception. Every day of my life has been painful and I was at the point where I was thinking of committing suicide. Now I know what it is, I just want to get better. I'm in the middle of a formal complaint about the bastards that gave it to me. All doctors love this injection and hate it if you show any doubt about it. These doctors are pricks. DO NOT USE IT. Its not worth it. I wish I just stayed on the pill. If you didn't know, this injection is used to castrate peadophiles. Bare that in mind. F 19 2 years
9/6/2006
Email
 1  so I would no longer get my period. I super regret taking this shot. No one warned me! My breasts hurt, joint pain, headaches severe acne, and mood swings from Hell. I never had acne issues before this shot and my face turned super oily and filled with white heads! I feel so insecure! I'm so afraid it will leave scars, I made an appointment to get acne medication till it's out of my system. The worst part is having uncontrollable anger. I told my to f off last night - TWICE. I feel so bad! I can't believe I said that! My sister took this shot and had no issues so I figured I'd be fine. NOPE. I have been avoiding my boyfriend and friends because of how psycho I am and disgusting my face is. I have severe depression and seriously considered suicide. I'm only a month in and I don't want to go on another two months of not being able to control my anger and hurting people. I am so not this person this shot is making me. Don't get this shot. Just don't even risk it. It has destroyed my entire fucking summer. Oh and it didn't even so what it was supposed to. I had nasty dark discharge for over a week. With horrible cramps. I'm not even sexually active! And with my face like this and gaining weight slowly? That might STAY that way. Don't do it. Just don't. F 19 3 weeks
6/30/2013
Email
 1  Prevent pregnancy This shot makes me have horrible mood swings and it messes with my depression and makes me feel hungry all the time and I have pregnancy side effects. F 19 3 months
4/26/2012
 1  Contraception Had this injection once, 3 Months ago yesterday! WORST Choice I ever made!! Literally 2 days after I had the shot I just felt different, hard to explain but I just was not myself, I literally thought I was losing my mind, had no appetite whatsoever have lost over a stone, constantly crying & no idea why, paranoid wreck, became depressed, almost completely destroyed my relationship because I became so insecure! It was hell, and when I tried to explain this yesterday to the doctor at family planning they laughed & looked at me like I had 2 heads! I wasnt warned of any side effects! I am now back on the cerazette pill that didnt agree with me before but anything has to be better than depo, do NOT put Yourself through it!!! F 19 3 months
6/20/2013
 1  Birth control This shot is horrible. I do not recommend it at all! The first shot i had made me bleed until i got my second one (three months of a never ending period.) I was also an emotional wreck. I'd cry over the stupidest things. The second shot, the periods stopped, but I got ovarian cysts. Excruciating pain from the cysts rupturing, lack of sex drive, crazy mood swings, depression (and I have that already, so the depo provera just made it worse), anger, constant anxiety and panic attacks, and much more. Do NOT get this shot. I turned into a crazy bitch just from two shots! I'm currently on ovcon (pill), and it's so much better. F 19 6 months
6/18/2013
 1  period regulation, birth control Hair loss, lowered libido, aggression, depression, weight gain, moody, Breast tenderness, headaches, increased appetite, fatigue, lack of periods, pain around injection site, cramping, spotting, weakened bone density. Horrible horrible Birth control I experienced all these side effects from Oct 2011 until now they just linger like crazy. I haven't had a shot since Oct 2012 and I'm still experiencing these side effects. Worst ever!! I switched back to the pill...levora. F 19 1 years
??
2/10/2013
Email
 1  Birth Control Beyond terrible, an intense amount of pain, constant headaches and mood swings are awful. This is ruining my life. Bled for 3 weeks straight with lots of abdominal pain. No one should take it F 19 2 months
9/16/2016
Email
 1  contraceptive Constant headaches,nausea,loss of appetite,constant bleeding. With this shot I felt sick all the time. If it wasn't a headache I felt like I had to vomit. The last time I was on the shot before I had my daughter I got sick really bad around the time of my next shot. It was horrible. F 19 3 months
2/22/2016
 1  Prevent Pregnancy The first weeks since the shot I was normal everything was good but when I got my period that month I began having anxiety attacks, heart palpitations, migraines,insomnia, horrible depression, was extremely tired, hair loss I have bold spots since then!, I lost twenty pounds in two weeks, I've been so weak. In the beginning I seriously thought I was dying! This is poison my mental health has never been this bad and I regret taking this so bad. It really just depends on your body it may work for you. My sister has been on it for two and a half years with no side effects. I do keep telling her to stay far away from that as possible but she wont listen. I lost my semester of college because of this I really hope they had something to give us for this but with what I've been reading you just have to wait for it to get out your system. F 19 3 months
1X O
5/24/2018
Email
 1  Birth control Extremely tired. Loss of appetite. My mood is fine. Some days are better than others. F 19 18 days
1X M
8/18/2020

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