DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Contraceptive Major mood swings. I can be sad one second and totally flip out on my fiance. No period for the entire time but severe & painful cramping. My breast/ nipples were so sensitive that I couldn't even put on a bra with out it hurting. Also, I was stuck with these symptoms for 3 months!! It was a nightmare!!! Do NOT use this birth control! DO NOT USE THIS BC!!!! F 18 3 months
1X M
9/4/2011
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 1  I don't want my ego prego. DON'T take it. My mom got me on it at age 16 and it made me the most miserable person ever. I'm actually very scared right now. I bleed constantly and my back kills like no other. I went off it once and I didn't bleed for months it was nice but then I actually had to have it and now I have mood swings and pains all day everyday. Everything bothers me. I've been bleeding for 3 months with period symptoms. I hate my life. I'm too scared to see a doctor so I guess I deserve this. F 18 3 years
1/16/2012
 1  Birth control Joint pain in knees, extreme fatigue, angry, crying for no reason, constantly hungry, feeling pregnant and depressed, constant breakthrough bleeding, decrease then increase in sex drive. I'm only 18 and am having very bad pains in my knees anytime I try to get up. I am so tired it's unreal. Im starting to fail all of my classes in college because I prefer to sleep instead of do homework. The tiredness is a big factor for me, it's also making me very cranky and angry ALL THE TIME and starting to ruin my relationship with my boyfriend. He's starting to say things like, "You never used to yell at me like this" or "You never used to act like this" If my boyfriend is at work and im home alone, most likely im crying for no reason. I feel very ugly and unhappy with myself now. Always seem bloated and craving foods, wanting to eat all the time! The day I got the shot it stopped my period immediately but as soon as my next period came around its been constant bleeding or breakthrough bleeding (which is a very dark mucus looking blood). I've had it for about a month now. The first month is when I cried alot and felt very down on myself at all times which made my sex drive completely disappear. I didnt want my boyfriend looking at me while I change, we stopped taking showers together, we stopped kissing and everything. But now it's kind of changed, I want sex all the time now, literally every second I see him, I'm making moves. It's a bit rediculous. The problem with that now though, is that since im constantly bleeding, we can't ever even have sex because it's pretty gross. So it's like im going through this all for no benfits for myself. F 18 2 months
1X AN
2/26/2012
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 1  Prevent pregnancy Extreme breast tenderness, tiredness, depression, dizziness, low libido, hot flashes, nausea, no energy. F 18 1 years
1x
2/28/2012
 1  Prevent Pregnancy I was on the depo provera shot for three years. I have to admit that while i was on it i loved it, i didnt have my period the entire time and experienced some weight loss. I got off of the shot a little under a year ago and have been experiencing terrible side effects ever since. I have gained 30 pounds, heavier periods, and severe cramping. The weight has made me very depressed and just wont seem to go away. F 18 3 years
2/15/2005
 1  to prevent pregnacy exreame vaginal cramps with continuous bleeding it's just not worth the risk i've been bleeding for a month.....this time F 18 1 years
2/10/2005
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 1  Birth Control I experienced anxiety, depression, weight gain, loss of bone calcium even though I took calcium supplements, irregular periods, and estrogen dominance. After discontinuing my injections, I have been experiencing pregnancy symptoms even though I am not pregnant. My body had started to mimic menopause while on depo which is what worried me and caused me to discontinue it. I am now worried that my ovulation and fertility will be damaged permanently from this drug. I was not informed that Depo should only be taken for 2 years, after being on it for 5 I am horrified as to what this has done to my body. When I started Depo I thought wow, I won't get pregnant and my periods will stop. After 5 years of injections I am now worried that I will never get my periods back to normal and my chances of having children will be compromised. If someone had told me this when I first started I would have never agreed to let a doctor inject this into my body. F 18 5 years
3/13/2005
 1  Contraceptive/No period About 30 lbs weight gain, extreme hair loss, total loss of sex drive, loss of lubrication,I freak out over the smallest things, depression, constantly hungry, insomnia, bloating, fatigue. I started taking depo because I was starting to getting into a serious relationship and didn't really want to worry about getting pregnant and the no period thing was awesome. But the only thing my doctor told me was that I might gain about 5 pounds. yeah right!!! My now husband thinks that I don't really want him anymore, and when we do attempt to have sex it's very painful. I have always had thick hair but since I started taking the shot my hair has thinned out a lot. I still get my period right before I'm due for another shot and I never really had severe cramps bfore, but now it's terrible almost unbearable at times. My muscles ache almost all the time especially my back and neck area, My bra size used to be a 36C now it's a 38C. Just about everything seems to get me down. But the crazy thing is I know I'm not pregnant but it sure looks like I am. I am due for a shot in December but I'm not going back. Taking this shot was the worst thing I have ever done and I really don't recommend depo for anyone. F 18 1 years
12/8/2004
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 1  contreception constant bleeding,memory loss,anxiety,difficulty speaking/ thinking clearly,depression this stuff is absolute shit! DONT GET ON IT!!!! the doctor told me all his patients loved it and never had a problem w/it so i started taking it and have had my period the entire time on my first shot i went from a size 6 to a size 9 then when i was sopposed to get my next shot i started stuttering and messing up on words and stuff i couldnt think clearly at all it felt like i was losing my mind then i got my second shot late and it went away they told me it would help the bleeding but its just the same as before i also went from a size 9 to a size 3 this time cuz i went on a diet ( depo makes you gain 200 cals on top of everything you eat) and i feel anxious all the time its almost time for my next shot and im starting to have alittle trouble thinking clearly but nowhere near as bad as before i think im gonna get on b/c after 12 weeks and see if it helps i will NEVER do this again F 18 6 months
5/10/2005
 1  Birth Controll Severe depression(which I had to begin with this made it worse), EXTREME irritability, Lowered sex drive, lack of energy, pain in left side of my body (mainly my joints, specifically ankle, knee, wrist, and elbow.)Mood swings, Loss of appetite, weight loss I thought this would be a great idea but I was wrong, I got the shot and that same day my moods starting shifting crazily. This shot is causing nothing but trouble, its put my realtionship with my boyfriend on rocky ground because everything he does irritates me. which it never used to untill I got this. I can hardly stand for long cause my left ankle and knee hurt so bad, and my left wrist aches so much I try to avoid using it. ONly 2 more months of this crap. I'm going back on the pill, this crap isnt worth it. F 18 1 months
5/25/2007
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 1  birth control pregnancy Have been on the shot for a long time, had punctual injections, never took antibiotics.... and I found out 3 days ago that I'm 4 weeks pregnant.... THANKS DEPO!!!!!!!!!!! F 18 1.5 days
3/15/2008
 1  birth control, heavy painful period depression, anxiety, panic attacks, paranoia, but NO period i had no idea that depo could mess with your head.ive just come off it coz my partner an i want to have a baby. my depression and self esteem levels are out of control and i really do think im going crazy! also, i had no idea that it would mess with my body so badly. i havnt bled for 4 yrz. how can that be healthy? i was young when i started taking it and im stil young now and im not impressed with how little info i was given F 18 4 years
3/22/2008
 1  Birth control Itchy rash at injection site that lasted 3 months, severe panic attacks, depression and anxiety that I never had before and am now being medicated because of, shoulders and neck hurt like hell, cysts that burst on my ovaries, displaysia of my cervical cells that could lead to cancer, no motivation, memory loss, chest pain, sweat, weight gain. I never thought it could be this causing everything until I saw this site. Do not take it. Ever. It has made me violent. I have scars on my feet from kicking holes in the wall. Before Depo, I never would have done anything like that. I am a completely different person that I can't stand. I have an increased risk of cancer due to abnormal cells. My knees and shoulders hurt like I'm 80 years old. I have been to the emergency room for cysts bursting on my ovaries. I have severe panic attacks where I can't breathe. I went from 120 to 145 and haven't changed my diet. The first time I took it I had a rash on my butt that itched for 3 months. That didn't happen in my arm. I live in pantyliners. I have no motivation. I was valedictorian in high school and I failed out of college. I could sleep for 15 hrs. at a time. Seems like the majority have the same problems. Let's sue the bastards. F 18 2 years
1/29/2008
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 1  Pregnancy Prevention headaches, HORRIBLE weight gain, NO sex drive, period for 5 months straight. I began getting the shot on my doctor's recommendation. Since the first day i got it seven months ago, I have had my period. Not just spotting. The worst is the horrible cramps! I never had cramps before going on the shot. I've been to my doctor and she told me my period would go away after the third shot. It didn't. In fact, It got worse. I will not be going back for my next shot and I would not recommend it to anyone! I went from 114 pounds to 140 pounds from being constantly hungry. I am an active person taking care of my horses and running every other day. And even that hasn't saved me. F 18 7 months
11/29/2008
 1  prevent pregnancy Most of all I gained weight! I am 5'5 and I went from a skinny 117 to a big 180! My body looks so bad from all the stretch marks. Other than the weight which is bad enough, extreme vaginal dryness, decreased libido, I now have hypertension, and moodiness which also caused extreme jealousy. I quit doing Depo and ever since I can tell the difference. It was the worst mistake I made in my life. F 18 1.5 years
1/16/2009
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 1  birth control nausea, headaches, fatigue, hunger, muscle ache, frequent urination, moodiness, depression, weight gain, acne. i have never been more miserable. my doctor only briefly warned me about a little weight gain and spotting, but ive had no period at all. that would be fine if i wasnt so worried about being pregnant now. this has been the most stressful experience of my life, i would rather have had a baby. F 18 30 days
2/3/2009
 1  prevent pregnancy chest pains, hunger, painful sex, constant bleeding that hasn't stopped, lost some weight. The first three months on the shot I was on my period everyday except maybe 2 weeks in the begining because i switched from the pill. Im currently still on the shot. I only have one month left and I am going to stop taking the shot. F 18 5 months
4/4/2009
Email
 1  Birth Control Huge weight gain, mood swings, allergic reactions, no period DONT USE DEPO-PROVERA! I had my last shot about 3 months ago and my last period was in January, i've gained over 15 pounds, im misserable because of it and have bone pains sometimes. I don't believe its a healthy or safe birth control. My suggestion is wear a condom or just wait. F 18 3 months
8/2/2009
 1  control periods / endometriosis weight loss of about 22 lbs., extreme hair loss, terrible mood swings, emotional, break through bleeding, depression, loss of personality, terrible pain, loss of appetite. I have had endometriosis since I was 14. I have had surgery twice and been on birth control pills. After my second surgery in June of '09 I was put on this shot. At first it worked great except for a few break through bleeding every now and then. I would say after my second injection I began to loose weight. I weighed 112 lbs. gained 3 to be 115 lbs. then lost 22 lbs. to now be 92 lbs. I am 4' 11 so this is not a healthy weight for me. I also began to have periods exactly a month before I got the next injection, and they would last 7, 14, and one time it lasted 17 days! I have always had a lot of hair but now it just falls out in clumps I cant even run my fingers through my hair anymore because I am scared it will just pull more out. After my third shot my friends and family began to notice that I was not my bubbly outgoing self anymore, I was just so tired and never felt good. My doctor says that this would have shown up after my first injection, but that is not the case. She also said if you are prone to depression the shot will pull it out, but im telling you I have never felt depressed or as messed up as I do now. I would get so upset over every little thing and could switch from being happy to pissed off in about 2 seconds. I was just not myself anymore and am tired of it. I will not take another shot after this one is over I will just go back on the pill. F 18 15 months
8/15/2009
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 1  birth control EXTREME DRYNESS leading to PAINFUL INTERCOURSE. causing me to stop sex mid way through.. loss of sex drive along with the pain made it very effective considering the thought of having sex made me cringe. 10-15lbs weight gain. some mood swings that leveled out after the first month. headaches, body aches. chest pain. bloating, gas, abdominal pain. I was on depo for 6months. and refused to get my 3rd shot because i was so dissatisfied. i was unsure of what was directly causing my side effects, but after finding this website i am convinced they are all caused from depo. i have been off depo for roughly 3 months, i have regained only a quarter of what my sex drive used to be, i have a hard time becoming aroused. intercourse is still painful, luckily my boyfriend is very understanding but i feel it is still straining our relationship.. intercourse feels very tight, even with the use of lubrication and easing his way in. after only a few minutes it begins to make me feel as though i am being "rubbed raw" inside and i have to ask him to stop. it is sometimes so painful that i am brought to tears.. i PRAY that this will go away. i feel dysfunctional. as for the weight gain, i do not know that all of it can be blamed on depo. i have now renewed my gym membership and working out 5-7 days a week doing cardio. i have lost the majority of what i gained while on the shot. i would never recommend the shot, and i wish i never had it. F 18 6 months
8/10/2009

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