DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  severe bleeding/cramps weight gain,hair loss,brittle bones,acne,bloating, I was originally put on depo because my monthly period was so severe in cramping and bleeding i couldnt get out of bed and was near blood transfusions. At first i loved it because i didnt get a period and the cramps were gone. I was 14 when i got on the depo and i am now 18.5 years old and just recently got off of it because of the horrid side effects and because my obgyn insists that i switch. now that i am off it(last shot was in august 2010) i now have worse cramps then i ever have before, it can take up to 9mnths to get my period and clean out, i am having vaginal pains, my bones are so thin and frail is unbelieveable and my body is just messed up. I DO NOT RECOMMEND DEPO AT ALL. F 18 4.5 years
1X day
11/29/2010
 1  To not get pregnant. nausea, BIG TIME headaches, stomach pain, Breast tender and hardness, Tired all the time, Not eating, Sometimes eating ALOT. I would not recommend the Depo shot to no one. When i got it i was excited, my periods were going to stop for two months and then come at the third month, which thats what the doctor told me. Which was NOT true. The first shot i got i was bleeding for 20 days straight and then Poof it was gone. When the third month came there was nothing. I was a little worried so when i went to get my next shot the doctor told me some girls dont even get their period for a whole year.. So i got the secong shot on march and ever since then i been so moody, i cry sometimes for no reason, i get mad at everything. I take it out on my family. am always tired i need a nap of three hours each day to feel good. and the headaches OMG i have them every single day. and they get worse if i dont take an Advil to stop it. Its been almost 8 months since i got the last shot. and i have no spotting or bleeding at all. am worried i dont wana get sick. am tired of these pains in my stomach and the hungryness i always get. Yet am losing pounds. Please girls dont get this shot, i really wish i didnt take it, but i did.. now i wish everything can go back to normal. M 18
1X day
10/28/2010
 1  Cease periods Extreme fatigue, lightheaded, joint and muscle soreness/stiffness, bladder pressure, constipation, excessive bloating, weight gain, anxiety, paranoia, depression, moodiness, acne, loss of tooth enamel, poor circulation PLEASE CONTACT ME VIA EMAIL ABOUT YOUR EXPERIENCE WITH THE LENGTH OF TIME IT TOOK TO FEEL BETTER! I need to know how long on average I will experience symptoms. If anyone could please contact me ASAP I would appreciate it. I am nearly suicidal over feeling helpless. I am constantly over eating. My life is on hold. I can't do anything normally or function like I used to. People tell me I seem dead already! F 18 47 days
150 mg 1X O
1/29/2011
Email
 1  Birth Control Extreme Fatigue, Body Aches, Change in mood, Abdominal pains, Appetite change. I would not recommend this form of birth control to anyone, because I started getting the shot having no ideal I would be the one to get side effects. I had been wondering why I was so tired and moody, and after reading all of these reviews, it made sense! I was not myself anymore, it was horrible. I felt trapped in someone else's shoes. I had no emotion most of the time, I wasn't excited about anything. I am constantly tired. My stomach would just hurt, worse than cramps for no reason. One day I would eat, eat, and eat. And others I would eat and want to puke. It has got in the way of my happiness and is effecting my relationship with my boyfiend. Although these side effects don't happen to everyone, I would not take the risk if I was anyone else. F 18 9 months
1X AN
2/10/2011
 1  Safer sex-no pregnancy too many to mention- a lot of fatigue please email me about your experience-especially if you feel better and how long that took. [email protected] F 18 75 days
150mg 1X O
2/27/2011
Email
 1  Endometriosis Weight gain 30 lbs. Hyper tension. Severe acne. Mood swings. Fatigue. Sweating alot. Bloating. I am 18 years old and was 130 lbs since I was 13 years old. I always had a very balanced diet and when I went on this medication I experienced extreme hunger. I exercised as much as I could until I noticed that my chest began to hurt. I remember it was May and I had prom in June and I was freaking out because I had acne all over my back and face. I never had acne before this medication. I called my doctor and I was told that it was a dermatologists problem. So now it's August and I went to my doctor to get another shot. I got weighed and gained 30 lbs in under a year even with exercise. I spoke to my doctor and asked her why did I gain weight and why was I covered in acne? At this point in time the acne was down to my wrists, on my thighs, chest, back, lower back, neck, scalp, and it was going onto my stomach. Now I am off the shot and dealing with acne, stretch marks (even though I lost weight), and depression. If you notice acne or any side effect if that, please get off this medication. I can't wear t-shirts or shorts even though I lost weight because of the severe acne. People ask me if I have hives or singles. To be perfectly honest I rather not take any pills at all and live with the consequences of my disease. At least I was still me and not some ugly monster that I am now just because that doctor didn't want to operate or refer me to a more experienced surgeon who could've gotten rid of the disease for good. F 18 1 years
1X O
12/21/2010
 1  Stop period, have unprotected sex Decreased appetite, nausea, lightheadedness, persistent headaches, bloating, abdominal pain and cramps, depression, anxiety, past suicidal thoughts, constant fatigue, excessive hair growth on face, bladder pressure, frequent urination and large amounts of urine disposed, additionally possibly contributed to yeast infection. My doctor told me symptoms were mild and I could possibly gain 3-5 pounds. She was wrong. I really wish I had asked more persistently about other side effects. I wish I had listened to my instincts and not have gotten the shot. I may have to live with these symptoms for weeks or months. I feel extremely discouraged and depressed, and I'm trying my best to be optimistic and lead my life as I did before. I do not want to gain weight as I am a heavy exerciser. This shot is life transforming. Unfortunately it's not helpful in my life and I strongly recommend not injecting one's body with powerful hormones. The Depo shot is like playing Russian Roulette. Please don't go for convenience, take something that can be neutralized or will exit the body shortly in case anything negative happens to you. I didn't think this would happen to me...and I'm sorry I was naive and blindsighted. F 18 2 weeks
Not sure 1X O
12/29/2010
 1  Prevention of pregnancy. Weight gain, irregular spotting, depression, insomnia, nausea. I absolutely hate this drug. It is a poison, and potential users should beware. I was attracted to this drug because of the elimination of my period. While that is a plus, I feel the negatives out weigh the positives. I became VERY moody, I would snap at people, the only word to describe my mood accurately would be 'crazy'. I became very depressed, I hated the way I looked, I hated myself, I would cry for no reason. I lost my desire for intimacy, I would have to force myself to want to have sex. And when I did, I was very dry and had to use lube, which my natural moisture has never been a prblem before. I began losing hair, I wanted to sleep all day, I would spot and have a very nasty brown discharge occasionally. In nut shell, this drug has wrecked my body. I will be happy when it is out of my system completely. F 18 6 months
1X O
1/21/2011
 1  prevent pregnacy mood swings, depression, nasia i would not recomend this to anyone. i wake up some mornings mad for no reason, and will stay mad for the majority of the day. i have horrible mood swings, many people have told me that i am i different person now that i am on the shot. and mind you i have only got it once, and im not returning for the next one. its not worth it! F 18 50 days
1 1X AN
2/16/2010
 1  Prevent pregnancy Weight gain. mood swings, depression, anxiety I used this birth control because my doctor recommended it to me over all other types of birth control. I have now been off of Depo for 8 months and I'm still suffering the side effects of weight gain. I know many will say a medication can't be blamed for excessive weight gain, but Depo is truly an exception. I had never ever experienced any weight issues before Depo and then over a span of nine months I went from 125 lbs to 170 lbs in size perspective 5 to an 11. I do not have a sedentary lifestyle and I have been fighting a long hard battle to try to lose this weight and it's been a challenge (I've only been able so far to lose 10 pounds) I recommend this drug to no one and I hope for those who are already taking this drug to please get off of it, there are other options. I made the switch to Mirena and have been much happier weight is still an issue for me but I no longer have experienced depression or anxiety issues. M 18 1 years
1X O
3/16/2010
Email
 1  birthcontrol severe rashes, vomiting and nausea - Not enough warning bad side effects F 18 2 months
1X O
3/27/2010
 1  Birth control Moodiness, anxiety, back pain, exhaustion, fatigue, etc I just finished my first three months of the shot and will NOT do this again. I am a very upbeat happy person and lately all i do is cry and have extreme anxiety. This shot has effected my job, and more importantly my relationship with my boyfriend who thinks i'm a crazy moody person nowadays. I do not recommend this shot. I can't wait for it to leave my system. F 18 3 months
1X AN
4/14/2010
 1  To prevent pregnancy After recieving the shot, I became very depressed. I have no sex drive at all, and I cannot get aroused. Me and my boyfriend had been together for a year before I got the shot and our relationship was great, not perfect but pretty close. And now we aren't together because of how depressed I am. I get mad at him for absolutely nothing. I feel justified in the moment but then when I think about it later I realize how irrational it was. I've completely stopped hanging out with friends I used to hang out with on a daily basis, I sleep every chance I get because I am so incredibly tired all the time. I've hadsevere back and knee pain. I never really thought that the shot was the cause of these problems, but after reading all the stories about the negative side effects I'm pretty sure depo has caused these issues. The one good thing about depo is that it does prevent pregnancy. A birth control that lowers your sex drive, whats the point in that? Me and my ex used to sleep together everyother F 18 7 months
1X day
4/18/2010
 1  birth control bleeding your life out,crying for no reason,loss of sex drive,tired weight gain, false pregancy signs i got the depo shot for the first time 1-21-10 OMG why the hell did i do that. Feb comes no period hmmm I thought i was pregant simply because the same signs I was having wit my 1st child was starting to happen so I went to the clinic and nope wasn't pregant I was jus starting to get serious with my bf and april came and I started my period no big deal I thought so I WAS WRONG I bleed something terriable for 2 1/2 weeks straight then when I finally stopped bleeding For 1 day I started again and for the whole month of april I bleed every 3 days. Then for like the last four days of the month no bleeding. Sex was horriable trying to make love to my Man was so hard because for the 3 days that I didnt bleed we tried but I just wasnt into it I layed there with no drive at all I felt like crap because Im in love with him and to fill nothing while you make love with you man is terriable. April 18th was the day I was due back for the shot did I get it HELL NO NO WAY I WOULDNT WISH THIS TO The PPL WE ARE AT WAR WITH if your doctor try to recommend you to this RUN & RUN FAST this is close to LIFE IN JAIL thats jus how bad this shot is. Imagine bleeding damn near every time after you have sex my boyfriend is the love of my life and guess where he's been sleeping on the couch. He is mad at my lack of drive. And he's been sleeping there on and off for a month May is here and I bleed for 6 days heavy and thought i WAS OFF but depo had a surprise for me I bleed right after intercorse. Mi F 18 1 times
1X O
5/7/2010
 1  birth control Severe anxiety, depression, hair falling out, nausea & vomiting, dizziness My 18 yr old daughter had 3 shots. After the 3rd one she began having severe anxiety attacks. 1 ER visit, 2 doctors visits, a multitude of medical tests (all normal), 1 psychiatrist & a prescription for antianxiety/antidepression medication later, she is finally starting to feel a little better. The psychiatrist told us that 60% of women taking depo will suffer from depression. So her last shot was 5/1/10 & she is still anxious & depressed but able to funtion (she has not been able to do anything with her friends all summer, has not been able to work). She has nausea every morning, hair is still falling out, vaginal bleeding every other day. This has been the worst time ever for our whole family. DO NOT GET THESE SHOTS, THEY ARE EXTREMELY DANGEROUS ! F 18
1X day
8/18/2010
 1  birth control irritable, paranoid, slight irregular bleeding, crying without reason, I would definitely not advise taking this. My emotions are up and down all the time. I feel like I'm PMSing. I have been crying ALOT. The bleeding has not been bad, not as bad as a period, and no cramping. I have also had no weight gain that I can tell. If the psychological effects weren't so bad I would keep taking this. F 18 3 months
1X O
3/30/2011
 1  pregnacy,stop painful periods pain in stomach, MAJOR mood swings, vaginal discharge, headaches, anxiety , random crying , EXTREME RAGE . okay im 18 & my boyfriend & i had experianced a pregnancy scare once before. i had heard about the depo shot i had decided to give it a try. it was the worst experiance of my life! the headaches seemed to never go away & the pain in my stomach would pop up at the most unwwanted times. my mood swings are the craziest things. i lost a few friends over it & i almost pushed my boyfriend away.it took two weeks for the vaginal discharge & the spotting to go away. my moments of rage & saddness were past random. i couldnt even eat infront of people because of my fear of choking. no matter how much sleep i got i was still sleepy! I DO NOT recommend this shot at all. im not going in for my 2nd shot so hopefully the side effects will wear off soon & i can get back to my old life. F 18
1 shot 1X O
4/1/2011
Email
 1  Stop periods and pregnancy So many for this long I decided to create a safe haven website for all suffering. Please visit, read, and join the only operating Depo Provera support group. SPEAKAGAINSTDEPOPROVERA.WEBS.COM F 18 112 days
150 mg 1X O
4/5/2011
 1  Stop pregnancy and period Extreme fatigue, lightheadedness, constipation, depression, pain in joints, bladder and abdominal pressure, frequent urination, bloating, Vitamin D deficiency, excessive body hair growth, body weakness, poor circulation, obsessive thoughts, extreme paranoia, increased acne, poor digestion, hot and cold flashes, mood swings, difficulty keeping visual focus, overall body aches, pain, and lethargy, thoughts of suicide, genital discharge, incontinence, insomnia, easy bruising, etc. I was highly active and very energetic, healthy, and not overweight. BECAUSE OF DEPO I HAVE SUFFERED SINCE BEING INJECTED. I have no doubts about Depo being the root cause of my symptoms. After going months and not knowing what was wrong with me, I went to a specialist. The endocrinologist ran tests, and diagnosed me with HYPOTHYROIDISM. No doctor, nurse, or lawyer will believe the Depo is the cause, but I know it is. I didn't develop any problems causing me to be confined in my house for four months. Don't let your belief be swayed because there are thousands of women who have suffered like I have. If you are having symptoms as I described, go to an Endocrinologist. You will likely get a diagnosis and get treatment before it is too late. I now have A DISEASE FOR LIFE. I will never take Depo again. All this lifelong suffering from a single shot. F 18 4 months
150 1X O
4/19/2011
Email
 1  horrible cramps and no pregnacy i have been bleeding since i got the shot im super mean mood swings hot flashes nausa it has been all bad i needed it because of cramps that would make me pass out and you could actully see move over my lower stomach but i have been bleeding for 6 months everyday im a total B**** i get sick to my stomach and i started feeling very depressed a weeks after i first got it but hey the cramps went away F 18 6 months
2X AN
9/24/2011
Email

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