DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2   Weight gain , acne , mood swings , depression . Before starting the depo shot , I asked about the side effects & my doctor mentioned weight gain . She said as long as I stay active & eat healthy, it shouldn't be a problem . Overall, I eat healthy & exercise often . I have gained about 30 lbs in about 6 months . I also get NO period what so ever . Although it's nice, isn't that unhealthy to not have one? I wouldn't recommend the depo shot & will not be going back for another shot :( F 18
1X O
10/10/2010
 2  to be more cautious. some side effects I have been having are, depression from time to time, some nauceousness, pins and needles almost 5 times a day (even in the back of my head??!) sleepiness, feeling very fatigue throughout the day, constipation, major mood swings, It's been a little over a month since I had received my first shot of Depo & just spotted a tiny bit this morning (i guess that's alright?)..I just don't feel like the person I was before taking it, no more shots for me. The main reason of why i mainly decided to take Depo is because my OBGYN told me it was my best safest bet since a recent abortion I had got in May & I'm not the biggest fan of having to remember to take a pill every day at the same time. F 18 1 times
7/22/2006
Email
 2  birth control light to medium bleeding for over a month, headaches, increased appetite, slight increase acne, tiredness, dizziness, mood swings. this is my first shot and these side effects are probably normal but theyre not worth it. its different for everyone. but ive been bleeding everyday since i got the shot along with the other side effects listed. i'm going on the pill after the 3 months is up. ive read so many better things about it and so many horror stories of the shot. please research it before considering it. it may work for you, it may not. F 18 1 months
1/5/2007
 1  Birth controll I gained 14 lbs in 2 weeks. It is March 14, 2006. My first shot ran out on January 18, 2006 and I didn't get another one. I have yet to get my period. F 18 3 years
3/14/2006
 1  to prevent pregnancy Severe depression and anxiety, always fighting with my boyfriend..always crying,moody,easily set off, lost my job because i was always in a bad mood, irritable. I've had pregnancy like symptoms, I almost always have a period. I took it in april 2006 and its now november 2006 and i am still not back to normal, I only took the shot once. I feel like im pregnant Im spotting like pregnant people do, my breasts are sometimes tender, im anxious all the time. My boyfriend of a year cant stand me anymore. Im scared to death all the time cause I feel like im pregnant even though a pregnancy test told me I wasn't. If anyone has any of the same symptoms as me I'd really like someone to talk to. This is really hard for me. you can e-mail me at [email protected] F 18 1 times
11/19/2006
Email
 1  britch control very bad abdominal pain, head aches, muscle aches, heavy almost constant bleeding I loved depo AT FIRST! This shot has sent me to the er 4 times now.... and i recently figured out it was the shot! i am always on my period and never want to have sex so in that aspect its a good bc but it sucks cuz i am going to lose my bf over it! i advise you dont do...there are other methods that you wont regret... F 18 2.5 years
11/11/2005
Email
 1  form of birth control well lets see i gained about 25-30 pounds and went from a size 1/2 to a size 5/6 deffinetly not happy of that fact, severe anxiety, mood swings, depression, weight gain, acne, decreased in sex drive, severe abdominal pain, muscle aches, memory problems... This injection has truly ruined my life..i went from a happy go lucky person to a being very depressed and a lot less motivated to do ne thing, not impressed with the weight gain, i have joined the YMCA hoping that i can loose the weight, i can truly say that it has ruined my relationships with my friends and with my more serious relationship with my bf, the depression has made me not want to do ne thing but feel tired and constant paranioa that bad things are going to happen to me, i feel i could have done better in school, and with my life..im proud to say that i am off the needle and back on the pill so im hoping that i will be back to normal soon! F 18 3 years
1/17/2006
 1  Birth control Horrible emotions, 20+ pounds weight gain, heavy, long periods, almost 2 months long at one point. Don't get the shot. It is the worst decision I ever made. F 18 6 months
10/19/2012
Email
 1  Prevent pregnancy Kidney problems, stones, migraines, brown clots, spotting, severe neck and back pain, very depressed, moody and dark brown discharge. Very bad acne(never had acne before), confusion and anxiety. No sex drive, pain during and after. Abdominal pain. Lack of interest in getting out of bed. PLEASE STAY AWAY FROM THIS DEPO-SHOT!!! IT WAS THEE WORST CHOICE FOR ME. My Gyno NEVER WARNED ME OF ANY OF THIS. Never even told me that it was BLACK BOX labeled by the FDA. never warned of any long term or even short term side effects please stay away from this drug it will not only ruin your body but take a huge toll on your relationship and family. F 18 3 months
90 days
6/8/2013
Email
 1  Forgetful w/ pill, shot convenient Weight gain, stomach pain after sex, low sex drive, vaginal dryness, frequent spotting and bleeding, depression, mood swings, and headaches. Would not suggest this birth control method to even my worst enemy. It should be off of the market because of the side effects. When I got my first shot, I weighed at 128. I'm only 5'1 but my curves spread out evenly so I didn't look fat at all. I didn't work out or eat too healthy before the shot. Just weighed my natural weight with no effort. Now, after three shots, I weigh nearly 150. I gained 30 pounds with absolutely no change in lifestyle. And that's not even the worst of the side effects. I can hardly have sex without bleeding everywhere, especially towards the end of the three month time in between shots. My "period" is completely unpredictable, ill bleed off and on, and I mean intense bleeding NOT spotting, for up to three weeks of a month. Also, there's intense stomach pain after sex to the point where I almost vomit. My sex drive has completely disappeared, which is not normal for an 18 year old hormonal girl in a loving relationship with a very attractive guy. The vaginal dryness is terrible, makes me feel like a post-menopausal woman. The worst of the side effects would definitely be the depression and mood swings. This recently started after my 2nd shot. Ill cry myself to sleep for no reason, I have a great life. Anything my boyfriend says can throw me over the edge and turn me into a raging b****. I recently stay F 18 9 months
1/15/2013
 1  Parents' choice not mine Hard to get pregnant now that I'm ready to start a family, extreme weight gain F 18 1 years
5/17/2012
 1  Contraceptive After An Abortion This Was The Worst Mistake I Ever Made, For The Whole Three Months On The 1st Shot Of Depo I Bled Throughout It All Always Had Mood Swings Was Constantly Emotional, I Only Had One Shot And It Was A NightMare I Was Due To Have My Second Shot In The End Of December 2011 but I refused to ever take that again its april and my body is still messed up and now I'm afraid it will take forever to get pregnant, its a terrible contraceptive method!!! F 18 3 months
1 Shot
4/3/2012
 1  Prevent pregnancy Weight gain from 108-123 so far. Eating constantly and always hungry. I am depressed. I used to be confident and happy but now I let everyone walk all over me. I'm emotional over anything and get angry over nothing. I have literally ripped the toilet paper holder and towel rack right out of my wall with one hand. I have pushed away the person I love. He thinks I'm a monster. My best friend would rather party than help me which makes me feel even more alone. I didn't realize what it could be until my mom said i needed to get off depo bc it changed me. I want to be happy again. I was a skinny, young, happy, confident girl that turned into a pudgy, tired, unmotivated, miserable person to be around. I feel bad for the people who have to put up with me. F 18 6 months
5/8/2012
 1  Prevent pregnancy Bled three months straight, made me sore with no sex drive, depressed with horrible mood swings F 18 3 months
30 mg
4/28/2012
 1  Contraception Loss of sex drive, severe depression, emotional numbness, Painful sex, lack of lubrication, lots of breakthrough bleeding, anxiety, weight gain, vaginal odor, fatigue, breast tenderness, joint pain, bloating, sore muscles, hair loss, abdominal pain, headache, nausea, acne all over my body, sweating, shortness of breath, blurred vision, chills, weakness, memory problems, and constant dark discharge I went to planned parenthood to get the Depo-Provera shot, and the clinician didn't even give me a pelvic exam! I had NEVER had one before, and she gave me the shot without examining me. Then she told me there were no side effects, just that it may cause bone thinning, and it will take 1 week to take effect. Within hours of getting the shot, my emotions were severely effected in a negative way, my body felt heavy, I was tired, and very hungry. The physical side effects wore off in a few days, but the emotional problems worsened. I was very angry, depressed, suicidal, anxious, and constantly on edge. After about a month and a half on the shot, I got a 3 week long period, and had deep brown discharge everyday for a month and a half after that. I didn't want sex at all, and even when I did sex was VERY painful throughout the three months on the shot. I am now feeling the 'detox' from being on the shot, and my anxiety is the worst its ever been!!! F 18 3 months
1/9/2007
 1  Extreme menstrual pain Weight gain, never ending spotting, always feeling faint, constantly feeling nausious, low self-esteem and back pains. I've been taking the depo shot for almost 6 months now and I have been spotting daily for the passed 5 months. I cannot go without wearing a tampon because I spot every hour at least. My doctor said it's "normal" but it seems it's never going to end. It's costing tons of money for tampons. Supposedly the depo shot does NOT slow down your metabolism, it increases your appetite and that is what causes you to gain weight. I call a bluff, my appetite has actually gotten smaller and I've been gaining tons of weight. I haven't even been able to attempt to have sexual intercourse because i refuse to do so while bleeding. It HAS helped my cramps, which is the main reason I'm taking it, but that's about all. I want to stay on it though because the cramps were so horrible, I never want to experience such intense pain like that again. Also, I thought the depo was supposed to decrease acne and help cure it but obviously not. :\ F 18 6 months
8/5/2006
 1  Birth Control I experienced a deacreased sex drive and severely painful intercourse! I have been to the doctors for painful intercourse and they never mentioned that depo could be the cause. They never found out the cause either and I still suffer from severely painful intercourse! Now I know that depo is the cause! I am getting off depo-provera and hopefully I will return to normal.My boyfriend thought that I just did not find him physically appealing and my boyfriend is HOT! It's not worth ruining a loving 4 year relationship! I only reccommend it to young females that are not in serious relationships, because it can ruin your relationship with your boyfreind. F 18 3 years
10/21/2004
Email
 1  dr recommended I am so scared for my 18 year old daughter, she is having heart problems, shortness of breath, sick all the time, can't keep food down,swollen breasts, depressed, crying all the time, she is not the same person she was 4 weeks ago, i am so mad at doctor for recommending this to her, she looks so sick and pale all the time and he says oh, i guess this isn't for you, but too bad you'll just have to ride it out! This stuff is so,so,so BAD!!!! She has lost her job and doesn't feel like doing anything, she has no energy and just lays around almost in a daze, I am so angry! this drug should not be out there F 18 4 weeks
11/21/2006
 1  ruined relationship due to loss lof depo has ruined my realtionship with my partner of 3 years. ive been off the injection for 2 years and im still experiencing loss of interest even aftert having sexual therapy. i wouldnt recommend this drug to anyone unless you want to ruin your life. its made me angry, depressed, alone, as well as a load of other things. STAY AWAY FROM DEPO> F 18 1 years
2/22/2007
 1  Prevent Pregnancy Headaches, fatigue (slept 12-14 hours a day during and after the shot - which is still happening), loss of sex interest, loss of lubrication, dizziness, extreme depression (crying for hours a day, every day - caused me to see a therapist). I couldnt stand people anymore, mostly my boyfriend. I feel that all of the sexual side effects and depression caused me and my boyfriend to break up. I also believe it caused me to become anemic. I feel dizzy, lightheadedness and sleep all the time. I will never recommend anyone to use this drug. It ruined 6 months of my life. And I am still getting the side effects. I also have tried to lose weight, including exercising for an hour 7 days a week and not losing a pound. It really messed up my body. F 18 6 months
6/1/2006

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