PROLIA Reviews (DENOSUMAB)Average Rating: 1.4 (285 Ratings)Filter ResultsCompare PROLIA with similar:
Type: Biological Drug
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Results are sorted by Date from oldest to newest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
Charts & graphs: Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR PROLIA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | osteo | I'm looking for anyone whom may have taken this injection. My doctor wants me to get the injection after trying Boniva and 2 other osteo meds that made me very sick. I'm a bit leery so am interested in any one that had side effects; good or bad. | F | 57 | 0 days 1X day | 7/16/2012 | 5 | Osteoporosis | Dosage: 2 sub-Q shots per year. I had one shot 2 months ago and haven't had any side effects at all, thank God! I hope it continues to be side-effect free in the future. I am almost 51 and I have osteoporosis. | I broke my ankle a few years ago just by rolling it off a sidewalk. It was very painful with a long recovery. This medication is supposed to increase bone density. There are also risks for one's blood calcium to decline while taking this medication. | F | 50 | 1 times 2X O | 1/31/2013 | 1 | osteoporosis | after one injection I have been diagnosed with BONJ | F | 53 | 1 times | 3/3/2013 | 1 | osteoporosis | No negative side effects with first injection. Side effects with second injection started one week after the injection and lasted about two weeks. The side effects were heartburn, vertigo, blurred vision. I visited my doctor and ophthalmologist. I didn't put the side effects together with the Prolia. After the third injection I had heart attack symptoms, Costochondritis (swelling of rib and sternum), pain in limbs. This is a wicked drug. My husband finally realized that with each injection the side effects were getting progressively worse. It helped the osteoporosis but I will not take any more. Frankly, another injection would probably kill me. I don't know what to do about the osteoporosis. My doctor is suggesting Evista but the reviews scare me. | F | 55 | 2 years | 4/10/2013 | 1 | osteoporosis | I have chronic pancreitis, and this stuff has REALLY made my pancreas hurt. It is swollen as is my whole belly. Plus, at three months my hair began to fall out and is is totally ruined now. I have approximately 1/2 left and what is left is porous and straw-like. I have also experienced very high anxiety. If you have other health problems, I do not recommend you take this drug. | This drug actually changes your hormones and 'shuts down' the body's natural sloughing of bone cells. The idea is to stop the sloughing, but not the making of new cells. Anything that works in this manner has got to affect other hormones. I'm scared of it. I will NOT do the second shot. The choice is brittle bones and my sanity or stronger bones...maybe....and I die of pacnreatitis or otheer problems. No thank you. | F | 5 months shot 2X O | 5/24/2013 | 5 | Previous hip fracture | Only side effect so far is a bladder infection. No pain, no rash, no jaw problems. Next injection is January 2014. | The injection was completely painless. I also enrolled in the Prolia Patient Support Program and now get periodic emails with information on exercises and resources. I also received two telephone calls letting me know that I might be eligible for free injections. But my insurance company pays 100% of the cost so I paid little attention to the information. | F | 64 | 3 months 1X O | 10/3/2013 | 1 | osteoporosis; post-menapausal | A few weeks after receiving my first injection, got bad back, hip, shoulder, leg pains. Also have had sores on my scalp, headaches that won't go away, insomnia, swelling of abdomen, ankles and feet. I am suffering from fatigue. I still work and walk my dog every day, but am not the same person I used to be. All of a sudden I feel much, much older than 63 years old. I will not get another injection. | F | 63 | 3 months 60 1X O | 12/12/2013 | 1 | Osteoporosis diagnosed 17 years ago | Swelling of ankles and feet, pain all over body as if bruised, cramps in feet, feeling confused, general tired feeling and lethargy. | Started feeling poorly after 3 weeks of the shot. I have taken all the other meds over the years and this was my last chance. I really hate to decide between this terrible situation I now experience or the chances of a broken bone. | 66 | 5 weeks 1X O | 4/16/2014 | 3 | Osteoporosis and severe Osteopenia | I felt very tired after taking the injection the next day and have had stomach pain and neck pain. I am young to have Osteoporosis and am having a difficult time finding anyone my age to find out the effects of taking Prolia for longer periods of time while still having a mensus. I also have Short Bowel Syndrome and Crohns Disease. | F | 40 | 1 times 60mg 1X O | 7/18/2014 | 1 | Osteoporosis | I got extremely lightly headed about an hour after I took it. I almost passed out. I have have back pain and been verry lethargic I woke up today with extreme hip pain Has anyone had a hip fracture ? | F | 45 | 4 days | 7/25/2014 | 5 | Osteoporosis | None | Have rated 'very satisfied' as I have had no side effects. Cannot rate its effectiveness until next DEXA scan, not due for 2 years. | F | 74 | 2 years 60mg subq. 2X O | 8/1/2014 | 1 | Osteoporosis | After the first shot my left ankle was very painful but I didn't make the connection. After the second shot both ankles are very painful and at night I have restless legs and burning ankles. Also have hip pain and have hardly slept since June 2. Also no pain medicine helps. | I wasn't given any information about this and unfortunately didn't research it first. There will definitely not be a third shot and I tell everyone about my side effects. Since the shots are given every six months I am hoping and praying that it will be out of my system at the end of the year. | F | 73 | 9 months ? 1X O | 9/11/2014 | 1 | Osteoporosis, severe | Felt a little flu-like for the first 48 hours, then the whole body pain set in. Much worse than flu all over pain. Then blood showed up in my urine. I was so sick, I could not tell my husband how sick I was. The symptoms lasted 48 hours. I reported issues to doctor's office, but got no response. I've changed doctors since then. | I cannot recommend this drug to anyone. | F | 60 | 1 days 1X O | 9/20/2014 | 1 | Osteopenia | Itching & sores | After a double mastectomy in 2008, I began taking Arimidex in 2009. For years my oncologist wanted me to take a bone-strengthening medication and I refused. In March 2014, I gave in to Prolia. Two weeks after the injection, I began to itch at my mastectomy scar. I ignored the itching. Two weeks later when I removed my bra, the right side was soaked in pus. After investigating further, it appeared to be from the injection. Meawhile, the itching spread from my chin to my waist. Saw a dermatologist who agreed it was the Prolia. It is now seven months later and I still apply a prescription cream at least twice a day. The fluid-filled sores were taken care of within two days of using the cream, but the itching continues with less intensity. NEVER will I get another injection of Prolia. | F | 67 | 1 times 1X O | 11/13/2014 | 1 | Osteoporosis | Immediately after my first dose my lips began to swell. This was followed by rashes that were very inflamed on my face, eyes and other areas of my body that became progressively worse. I had to be on prednisone for 8 mos. to control it. It took over a year after my first (and only) injection for the symptoms to subside. It is almost 2 years and I still have some lingering symptoms. I would not recommend prolia under any circumstance. It's like playing Russian roulette - you may be fine or you may literally end up going through hell. | F | 58 | 1 times | 1/22/2015 | 1 | Osteoporosis | immediately after the Prolia injection (that evening) I started to get jaw pain for about a week. I got the injection on November 18 and on the 23rd I had severe left lower abdominal pain that kept getting worse. On the 25th I was admitted to the hospital with an attack of diverticulitis for 6 days. I knew from a colonoscopy (2013) that I had diverticulitis but had never had an attack. I have been dealing with this daily and just had a CT scan and I see a surgeon tomorrow. Also, I have more jaw pain for several weeks from a gum infection. Needless to say, I will not have the 2nd shot and do not recommend this shot if you have any kind of illness. | I trusted my doctor that said it was highly unlikely that I would have side effects, maybe some red skin blotches, irritations. Yes, I was given the literature. Listen to the Prolia commercials and you will hear about the jaw pain and prone to infections. | F | 66 | 1 days 2 X year | 1/28/2015 | 1 | Osteoporosis | Took it yesterday. In the hospital today with HIGH Blood pressure and vertigo! This stuff is horrible! | Bad news | F | 79 | 1 days 1 shot | 2/20/2015 | 1 | Osteoporosis | 1st injection in July 2014. Several weeks later I developed severe joint pain. I thought I was having some weird arthritis flare up. I saw my family Dr. He put me on Prednisone. It worked until it wore off. Dr prescribed physical therapy. Sorry but you can't make this crap up. Put back on steriods. I unfortunately never connected the Prolia to my condition. It was 3 weeks later. My Dr didn't catch it either. I had my second Prolia injection on January 20, 2015. On February 2, 2015 I noticed a dime sized red rash on my knees and elbows. Some had big pustules. Oddly enough there was no itching and no pain. I still didn't connect to the Prolia. The pain and extreme joint stiffness would not allow me to get out of bed or walk without assistance. I've had two 10 day courses of Prednesone. I finished the last of it on February 27, 2015. I am again having symptoms. The rash has started and the stiffness is roaring back Oh, my Dr said to take motrin and Benadryl. yeah right | Be careful to know all the side effects of this drug. In many people the symptoms begin weeks after the injection. My Regular Dr finally figured it out The Endocrinologist that prescribed Prolia never returned my call. | F | 70 | 2X O | 3/5/2015 | 1 | Osteoporosis | I haven't started taking Prolia yet but that is what is suggested to me. I have taken Evista with very minor side affects - mild hot flashes. After reading 18 reviews where only 2 reviews appearered ok I don't think I will be taking Prolia. | F | 62 | 1 days | 3/12/2015 | 4 | Osteoporosis | None! Prolia has not caused any side effects for me. When I tried bisphosphates I experienced intolerable acid stomach and heartburn, which I had never had before. I'm very, very pleased with Prolia. | I am anxious to get another bone density scan to find out whether it is working. | F | 56 | 6 months 1X O | 3/31/2015 |
PROLIA (DENOSUMAB): Denosumab is used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause. It is also used to treat bone loss in men who are at high risk for bone fracture. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases after menopause (in women), as you age, if someone in your family has osteoporosis, or if you take corticosteroid medications (such as prednisone) for long periods. Denosumab is also used to treat bone loss in women who are at high risk for bone fracture while receiving certain treatments for breast cancer. Denosumab is also used to treat bone loss in men who are at high risk of bone fracture while receiving certain treatments for prostate cancer that has not spread to other parts of the body. This medication works by slowing bone loss to help maintain strong bones and reduce the risk of broken bones (fractures). Denosumab belongs to a class of drugs called monoclonal antibodies. It prevents certain cells in the body (osteoclasts) from breaking down bone. (Sources: U.S. Centers for Medicare Services, FDA)