ALDACTONE Reviews (SPIRONOLACTONE)

Average Rating: 3.1 (155 Ratings)

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 ANTIHYPERTENSIVES DIURETICS ALDOSTERONE RECEPTOR ANTAGONISTS

 Type: Rx Drug

  

ALDACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1983-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ALDACTONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ALDACTONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  acne and thinning hair WEIGHT GAIN - ABOUT 5 POUNDS ON MY 100 POUND BODY, BREAST ENLARGEMENT (A WHOLE CUP SIZE) BREAST TENDERNESS. FAT REDISTRIBUTION - INCREASED BELLY FAT. This is a terrible drug. It is a powerful testosterone, androgen suppressor. It causes rapid weight gain, fat redistribution and general flabbiness, as well as enlarged painful breasts. In short, it is a disfiguring drug. I don't know anyone who would trade a few zits for a fat, flabby body and enlarged, painful breasts. I experienced these side effects and am in my 70s.This drug is given out like candy by dermatologists who deny its very common and devastating side effects. Thankfully I only took it for 5 weeks (50 mg once a day) and eventually returned to normal. Many women are not so lucky and are permanently damaged by this supposedly benign drug. F 74 5 weeks
50 1X day
2/27/2023
 1  Bilateral primary aldosteronism Bad insomnia, dry itchy skin, hair completely dried out, constant tense/anxious feeling, hot flushes, upset stomach and nauseated feeling for an hour or so after taking, breast growth and increased sensitivity. Beware perimenopausal women, this drug will tip you straight into far more menopausal symptoms, the worst being insomnia. I'm going to try Eplerenone ... it's a lot more expensive ... but doesn't have the hormonal interference of Spironolactone. Spiro blocks progesterone and testosterone receptors and increases cortisol, as well as aldosterone. None of these are conducive to sleep and losing them definitely increases menopausal symptoms unfortunately. It did however work well to lower blood pressure caused by high aldosterone levels produced by malfunctioning adrenal glands. F 49 6 months
25mg 1X day
2/26/2023
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 1  High blood pressure Psychotic spinning, loss of appetite and faint nausea, loss of sexual function. Didn't reduce blood pressure. M 62 14 days
25 1X day
2/4/2023
 1  Acne Chronic headaches, fatigue, irritability, flat mood, anxiety, tingling sensations, tinnitus, overall aches and pains, chest pains, panicky feeling I used to have breakouts in my 30’s , more so than now. My dermatologist put me on this drug to “ calm down my pores”. I just assumed I was high in testosterone since I’m still breaking out at 50, occasionally having a zit or two once a month. I got my total testosterone checked during my first week on this drug, my number was 19! I’m actually low! I don’t have hormonal acne after all and this drug is specifically intended for woman who are. Testosterone is good for our bodies within normal levels ( 15-90). Ladies, get your testosterone tested before going on this pill. If it’s normal, then you’re acne is caused by something else, usually overactive oil glands. Dr’s should suggest or require their female patients get their testosterone levels checked before prescribing this drug off label. It’s no wonder so many people have adverse side effects!!! I’ve been off this drug for a few days and starting to see improvement, slowly. In my opinion and experience, this drug is dangerous and should not be taken lightly for those, including myself who are “ hormonal sensitive “. F 50 2 weeks
25mg
8/28/2022
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 3  inflammatory acne felt weird taking this for acne? tired, cramps were worse (fixed with gatorade), breast tenderness and enlargement it did its job for sure!! but the side effects were... yikes F 16 3 months
25 1X day
4/13/2022
 1  BP 10 kgs weight gain, breast enlargement under arms sore and red in both armpits . Skin under arms like flab M 74 9 months
12.5 mg 1X day
4/7/2022
 4  Female pattern hair loss and acne Muscle twitches, leg cramps Except for when I took accutane at age 20, my skin was so embarrassingly oily my whole life. It is so clear and smooth now, it's remarkable. My mother asked if I'd had work done. I've My hair ' ugh.. has been nightmare due to pattern baldness (androgenetic alopecia.) I've used rogaine and finasteride consistently for years with moderate success. Adding spiro has been a life changer there. My hair has stopped shedding as much and baby hairs seem a bit thicker. I wish I took this 30 years ago. My potassium remains normal, I've lost a few pounds. I drink an electrolyte drink (like Gatorade) in the afternoon that keeps the cramps at bay. I will continue to evaluate my side effects and blood levels, but right now the side effects seem worth it. F 50 4 months
100 1X day
3/20/2022
 1  Acne constantly peeing, light-headed, loss of peripheral vision, stomach/intestinal pain After having a terrible experience with this drug that landed me in the ER after taking it for a month, I found out that it is a hormone blocker and blocks testosterone production. This was prescribed by my dermatologist for minor acne around my chin but not once did they ever test for high testosterone to see if that was actually the cause of my acne. I stopped taking it 8 months ago and I am still going to the doctor to try and heal my gut from the damage this drug did to my digestive system. I still have abdominal pain. Do your research before taking this drug! Clearly, the doctors who are prescribing it do not... F 27 30 days
12.5 1X day
12/9/2021
 1  Acne No matter how clean I ate or the amount of exercise I gained 22 lbs in 3 months. I haven't had a period in 3.5 months. All in my stomach, butt, and thighs. Nothing fits me. I've been off for 2 months now and my weight has not gone down. Can anyone give me advice? My Thyroid is functioning properly. Testosterone is low and waiting on my estrogen test to come back. I've never had any of these issues before taking this awful drug F 42 4 months
100 1X day
10/13/2021
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 2  Heart failure Have gained 10 pounds always hungry am eating a lot of fruit but still gaining also I am very lethargic and need lots of sleep F 67 5 weeks
25mg. 1/2 1X day
6/15/2021
 2  Heart failure Have gained 10 pounds always hungry am eating a lot of fruit but still gaining also I am very lethargic and need lots of sleep F 67 5 weeks
25mg. 1/2 1X day
6/15/2021
 2  Heart failure Have gained 10 pounds always hungry am eating a lot of fruit but still gaining also I am very lethargic and need lots of sleep F 67 5 weeks
25mg. 1/2 1X day
6/15/2021
 1  Acne Bloating, weight gain, breast enlargement, fatigue Is wonderful for skin, but not worth the side effects. Was at 50mg to start and there was gradual slight weight gain and I didn't think anything of it. Then dr increased to 150mg and the bloating, breast enlargement and rapid weight gain began.. just thought it was due to COVID lockdown so just started eating cleaner, journaling calories and upping my workouts. After cutting my calories 500-1000/day and working out like crazy(HIIT, cardio and weights) I still gained 15 more lbs in 2 months time. That's when I started researching and saw these same side effects were effecting others. So I stopped it. 1 month in i don't feel like a blowfish, bloating in stomach has gone down and I've lost 5 lbs. I'll continue to workout and see if the rest of the weight falls off, but am seriously upset my dermatologist did not tell me this was a side effect. All she said when I asked her about side effects was that I needed to stay hydrated and may feel a little dizzy if I stand up quickly. After researching the medication side effects myself I see that there are WAY more side effect listed than she let on. Again, upset she didn't tell me up front of all of them- so much that I don't think I'll be back to her. F 43 7 days
50-150mg 1X day
6/15/2021
 1  Edema Lactic acidosis, ovarian cysts, ovarian torsion Within 2-3 months, developed an ovarian cyst that grew large enough to torsion, requiring emergency surgery. Two weeks post-cystectomy, developed severe abdominal pain requiring hospitalization; eventually found to be lactic acidosis. As lactic acidosis was diagnosed (confirmed by labs), a second large cyst had grown on other ovary, requiring cystectomy. At no point did any medical providers suspect spironolactone having any role. Discontinued Spironolactone and second cyst shrunk, disappearing entirely over one month period, and lactic acidosis dissipated. No large ovarian cysts or torsions before or since. Was concurrently taking Metformin ER for PCOS with Spironolactone. F 32 4 months
200 MG
5/26/2021
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 5  Acne Never experienced any side effects Amazing drug for acne! I'm so very happy with the results from it! It seemed like a weird drug for acne but it works! F 36 2 years
100mg 1X day
4/30/2021
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 2  Moderate to severe acne I wont ever take this again. I started getting random sharp shooting chest pains & some of the worst bloating/gas of my life. Then over the course of the 18 months I was on it I gained 40 lbs. The thing thats bothering me is as soon as I stopped it the chest pains went away & a few weeks later my bloating/gas went away completely. I have been off of it for 12 months & Im still struggling to get the weight to come off which is unusual, Ive always been able to whip myself into shape easily before this. And of course my doctor refused to believe it was the medications fault despite the fact non of this was happening before F 26 18 months
50mg 2X day
3/25/2021
 3  Hormonal acne Started slowly on this med at 25/day. Worked way up over 6 months to max dose of 200mg. Pro: skin has been getting progressively better, still mild acne but no more cysts that last for weeks and scar. Con: In the last 3-4 months I have gained 20-25lbs, especially in stomach, butt and upper thighs. Literally nothing I own fits. Cellulite where I've never seen cellulite before. Just finally realized this week it's the Spiro, I had no clue what was going on. Hoping the weights not permanent, also worried to go off and break out. F 30 11 days
200mg 1X day
12/8/2020
 2  Cirrhosis Male - caused breast enlargement and extreme tenderness. Controlled Oedema and Ascites but side effects unbearable. Also lost sex drive and noticed thinning of chest and underarm hair Ask doctor if any alternatives without extreme side effects M 38 90 days
100mg 1X day
11/6/2020
Email
 1  renal failure I started with 12 and half mg per day. It made me feel awful. Foggy, drowzy and confused. Eventually I made myself adjust to it but never felt better. Physician increased dosage to 25 mg and I feel worse than ever plus depression because I feel so lethargic. I do not like it nor do I feel any improvement in my symptoms. F 74
25 1X day
8/30/2020
 5  Acne Lost weight. Acne cleared up. Minor side effect: increased thirst. This is a diuretic, you will lose a significant amount of water weight. F 32 4 years
50 2X day
7/19/2020
  

ALDACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1983-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

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