NARDIL Reviews (PHENELZINE SULFATE)

Average Rating: 4.3 (150 Ratings)

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 ANTIARRHYTHMICS ANTIDEPRESSANTS

 Type: Rx Drug

  

NARDIL  (PHENELZINE SULFATE):  Phenelzine is an antidepressant (monoamine oxidase inhibitor). This medication treats depression by restoring the balance of certain natural substances (neurotransmitters) in the brain. Phenelzine can improve your mood and feelings of well-being. Usually, this medication is used in persons who have not responded to treatment with other drugs.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR NARDILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Panic disorder, Major Depression I'm no longer taking this medication. M 33
45 1X day
3/21/2024
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Patient History
 1  panic, GAD 15 mg- 3 days; no effect except felt strange on third day 30 mg- 6 days; depression (none before) , restlessness 45 mg- 2 days: depression worsen; restlessness worsen; insomnia After 45 mg, I had to taper down to 30 mg to 15 mg in just a few days because the restlessness and depression was out of control. Lyrica and Ativan helped with the anxiety. As I was tapering down, I experienced a fast heartbeat for days. When I couldn't stand it anymore, doc prescribed beta blockers to control it. Thought I could go cold turkey after two weeks and some weaning, but couldn't do it. Couldn't feel my hands and had the craziest sensations that almost drove me mad. Felt slightly better after taking 15 mg after two days of stopping. The scariest thing was the insomnia. I didn't sleep for about 5 days; 5 -10 minutes for two nights and 0 minutes for the rest. I took sleep aids, benzos, lyrica, melatonin, 25 mg Seroquel. NOTHING! I was so scared that I had developed fatal insomnia. Even if I was s F 3 weeks
15 3X day
8/28/2018
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 1  Panic, GAD Depression, extreme anxiety, restlessness After taking it for two weeks I decided to stop it cuz it gave me insomnia after a bad reaction in my sleep. Something happened that night and now I can't sleep besides dozing off once in awhile.i haven't slept normally in days and I think it gave me fatal insomnia where the person will eventually die from not being able to sleep. Electric acupuncture is letting me buy some time with micro naps for a minute or so. No acupuncture means no dozing or sleeping. Sleep aids and even antipsychotics can't make me sleep . Its crazy bad.I'm seeing the doc today about this. I went off of it for a few days and not much change. I'm also getting crazy withdrawals like crazy anxiety and having weird numbness in my hands that is unbearable. After two days of hellish withdrawals, I went back on 15 mg. Hand numbness much better but now I'm no longer tired or sleepy. I went off of it cuz my heart wouldn't stop racing. Drug too stimulating.doc gave me beta blockers. Suicide on my mind almost every minute. F 33 3 weeks
15 mg 2X day
8/27/2018
 1  Depression Nervous Paranoia, not able to think clearly This can be a very valuable drug for depression and even personality disorders but be careful if you have schizophrenia. M 50 7 days
15 MG 1X day
9/30/2014
 1  Major Depression Dizziness, Extremely Low Blood Pressure/Fainting, Severe Constipation w/ Anal Fissure, Anxiety Attacks, Abnormal (for me) Thougts/Writing, Weight Gain, Night Terrors so frequent and traumatic that I became sleep phobic. Feeling psychotic. My tme on this drug was the worst six months of my life. Over time the psychiatrist was prescribing so many other drugs to combat the side effects; Florinef to keep my blood pressure up and stop the fainting, Sleeping pills and anti anxiety pills so I could sleep, vitamins for my electrolytes that were tanking and finally an anti psychotic! I became more sick on this drug than without it. After passing out and not coming to this time I was rushed to the hospital. I saw a psychiatrist there who told me that my dose was too high and I was having a toxic reaction, not becoming psychotic. He took me off the drug and while I still had to deal with the depression, all the side effects vanished and I didn't need all the other drugs. I was 19 years old and on 75mg per day. F 19 6 months
75 1X day
4/9/2013
 1  Severe depression/social anxiety Other than wanting to violently kill myself, none I was so disappointed. I was so pumped to try Nardil but it gave me strong suicidal urges and I had to stop after just 8 days. :( Big downer. M 19 8 days
15 2X day
1/14/2013
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 1  Severe Post Traumatic Stress/Depres As I increased dose fainting and seizures started becoming a problem. Ended up in the Emergency Room after having 2 bad episodes in the space of 3 hours. I naturally have quite low blood pressure 120/50 but my blood pressure was dropping to under 90. In the emergency room, through consultation with my GP and Psychiatrist it was agreed to drop dosage down to 30 mg twice per day. A week after being in the ER I had an unstoppable seizure, went from arms, legs and head flailing about uncontrollably to being stiff as a board, neck back. An ambulance was called, they were unable to stop the seizure so called for a second ambulance. They put a breathing tube down my throat in case everything seized up. By the time I arrived at the hospital I was unable to breath and the seizure contunued. I was placed in an induced coma in the Intensive Care Unit for 2 days and then was placed in the Critical Care Medical Ward for a further 2 weeks. I had one more seizure while undergoing rehabilitative Physi Prior to all the horrendously bad stuff happening, when I was taking my full dose of 90mg per day I was feeling the best I had ever felt, certainly not 100% but soooo much better. When the dosage was dropped to 60mg per day, I noticed a considerable downturn in my mood and behaviours - Binging on food, feeling miserable again, terrified to leave the house, buying random things uncontrollably. Would I recommend Nardil? Yes I would, the things that happened to me was not the norm and before it happened I was feeling better. I had taken so many different other types of anti-depressants before this but nothing helped me. F 42 6 weeks
45 mg 2X day
12/17/2011
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 1   DEATH (friend of mine made a suicide after a year on this drug he couldn't stand side-effects anymore). THIS IS BAD, OLD AND DANGEROUS DRUG. The ratings with this drug (as with many psych drugs) is WRONG. Psychiatry is full of lies and don't blindly trust anything you read from internet. M 30
1X day
7/22/2011
 1  Depression loss of affect, sleeping constantly, sensation of electrical shock, tardive dyskenesia. I stopped taking it when my arm began swinging out without volition, and the symptoms stopped. F 60 60 days
1X day
6/27/2011
 1  Depression DEATH - my friend died from this drug. My friend was taking Nardil for depression. She had an allergy and took half an antihistamine. Her blood pressure shot up, she got a cerebral hemorrhage and died after being in a coma for 2 weeks. This drug is VERY DANGEROUS and should not be prescribed to anyone. F 32 2 years
15 4X day
10/31/2010
 2  Depression, Headaches Burning mouth syndrome, itchiness, exhaustion, restless sleep, irritability it has been helping my headaches a lot actually but im so itchy ive scratched myself until i bleed, im so tired all the time and im always irritated because of it and my mouth and nose burn all the time. i want to stay on so bad because i went from daily migraines to a few a week but these other effects are getting to me, had good results with selegiline patch but terrible rash, going to try parnate next and seeing a specialist for nerve blocks in my head F 26 14 days
15 1X day
6/22/2023
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 2  Atypical Depression Repeated fainting/falling upon standing that didn't seem to go away with time resulting in many bruises & bumps to the head. Tiredness during day. Complete lack of headaches (good). Wanting to sleep all the time. Super low blood pressure even after activity. General coordination problems at 60mg which I was only at briefly-even trouble staying in lane while driving. I think it was helping with my depression, but the low blood pressure/fainting/falling was too dangerous & unnerving to remain on a therapeutic dose. I am on 22.5 mg now just to get by till my next dr's appt. Parnate is next. No food interactions, but I stayed away from restricted foods. Still feel it is worth trying for anyone that hasn't responded to other meds. F 35 90 days
15mg 3X day
6/14/2010
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 2  Panick attacks and depression None of the spacy feelings I had with ssri's. I felt sleepy during the day and had difficulty sleeping at night. I eat pizza and have the occasional glass of wine with no problem. I developed a sore throat and sinus infection about a month into it and have been extremely fatigued. Has not helped with mood at all. Anxiety is the same, maybe a little worse. I also take Klonopin for anxiety ( have been on it for years) M 39 6 weeks
1/19/2007
 2  depression very intense low blood pressure causing fainting, sleepiness...although i was taking a few other prescriptions with this drug (as prescribed by my doctor) it is possible that this caused tardive dyskinesia. intense sleepiness during the day for the first month, and sleeplessness at night for a year. i had to take other meds to help with the sleepiness/insomnia. the diet is very difficult. especially since i am a vegetarian. i had to start eating meat again...and ended up in the hospital for three days after a food reaction. i never want to repeat that experience again. especially since the doctors and nurses in this particular emergency room were not that familiar with MAO inhibitors, and i had to tell them what was going on with me. F 30 2 years
7/12/2006
 3  Depression social phobia, anxiety Nardil is crazy effective...helped a lot. As time went on it became less effective. The side effects of weight gain, massive hunger and orthostatic hypotension were very hard to live with. Now I manage with high dose effexor, high dose testosterone, valdoxan at night. No alcohol, carnivore diet. Regular strenuous exercise. If you just want to take a pill nardil will help. If you want to truly recover you need to attack from many angles 35 5 years
45 4X day
7/15/2020
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 3  depression anxiety, panic I am getting off Pristiq now to get on Nardil. PLEASE tell me it will work. I have tried it all this year...except antipsychotics. I have anxiety that builds to hysterical crying most days, that leads to severe depression ND suicidal thoughts. I have 3 small children and I am barely hanging on. F 37 1 days
30 MG
3/27/2016
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 3  Treatment resistant depression Lots of side effects: hypotension, insomnia at night, sleepiness during the day, lack of sex drive, headaches and dizziness initially that have since gone away. But by far the worst side effect so far is the muscle tension. I curl my toes as tight as they'll go, my jaw clenches uncontrollably, the muscles under my chin clench, my hands sometimes curl and distort. I'm a little concerned that it's some kind of tardive dyskensia but I left a message for my doctor 5 days ago and told him if I need to change something or stop taking it to let me know. So far he hasn't gotten back to me so obviously these symptoms aren't too worrisome for him. No one else has posted these symptoms except a couple with jaw clenching. Anyone else experience these? Do they go away with time? Seems to be helping sometimes but other times I'm right back to feeling worse. Not sure yet about it's efficacy. F 31 1 months
75 3X day
3/2/2016
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 3  Depression,anxiety, chronic insomni I had the most horrendous headaches on this drug which affected my stomach as well. It worked on the depression well but I had to quit because the headaches were so horrible that they lasted weeks after I had stopped the nardil This medicine would have perfect except for the horrendous headaches. I started being able to speak like I used to and lifted the depression etc but it was horrible headaches I had. F 59 30 days
45 4X day
4/25/2015
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 3  Anxiety / Depression Insomnia, weight gain (15 lbs), bloating, constipation, sexual dysfunction, fatigue, low blood pressure Nardil worked well the first time I took it, which lasted for a year until it didn't seem to help me when stress at work was getting bad. I switched to Marplan, which was awful, and then to Parnate. After about nine months on Parnate I became chronically fatigued, had trouble concentrating, and felt agitated all the time (too much NE), and eventually left my job due to poor work performance and worsening symptoms. I eventually switched back to Nardil, but it never worked like it did the first time I took it. When my pdoc and I pushed the dose to 75 mg I became hypomanic and very irritable/aggressive. I eventually experienced a mixed state that lasted for a few weeks. I also experienced brain zaps while coming off Nardil, which I've never experienced before with any other meds (Parnate was a pain to discontinue, also). I discontinued the drug quicker than recommended, over the course of about 2-3 weeks. M 34 5 months
30 2X day
2/24/2015
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Patient History
 3  Major Depression Weight Gain, Constipation, Sexual Side Effects, Insomnia I have been taking Nardil for almost three years - it made me gain about 30 pounds and I have trouble sleeping (I wake up 2 - 5 times per night). However, it is the only drug (out of about 30 of the SSRI's, SNRI's, tricyclics, atypical antipsychotics, etc.) that has worked satisfactorily for me. M 26 3 years
30 Mg 3X day
2/27/2013
  

NARDIL  (PHENELZINE SULFATE):  Phenelzine is an antidepressant (monoamine oxidase inhibitor). This medication treats depression by restoring the balance of certain natural substances (neurotransmitters) in the brain. Phenelzine can improve your mood and feelings of well-being. Usually, this medication is used in persons who have not responded to treatment with other drugs.    (Sources: U.S. Centers for Medicare Services, FDA)

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