NARDIL Reviews (PHENELZINE SULFATE)

Average Rating: 4.3 (150 Ratings)

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 ANTIARRHYTHMICS ANTIDEPRESSANTS

 Type: Rx Drug

  

NARDIL  (PHENELZINE SULFATE):  Phenelzine is an antidepressant (monoamine oxidase inhibitor). This medication treats depression by restoring the balance of certain natural substances (neurotransmitters) in the brain. Phenelzine can improve your mood and feelings of well-being. Usually, this medication is used in persons who have not responded to treatment with other drugs.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8


RATING  REASONSIDE EFFECTS FOR NARDILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  anxiety, depression They say Nardil makes you gain weight but I lose weight every time I'm on it. I lose about 10 poundsd, which makes me svelte. The only problem I had was insomnia, which is cured by taking Seroquel (150 milligrams). The other big thing before I forget is a tremor. What on earth do I do when my hands and face are shaking. what can I do for the shakes? F 5 days
3/26/2007
 5  Depression, severe anxiety, ADD constipation, hypotension, insomnia, dizziness, mild euphoria Nardil saved my life. I have tried everything and nothing has worked until Nardil. M 12 months
75 1X day
2/5/2017
 5  Social anxiety,depression Worked well for me, until formulary was changed.now it doesn't work well. Made me gain weight F 21 years
15mg tid
5/16/2018
 3  Treatment-Resistant Depression Severe swelling of legs & feet; chills; insomnia; blood pressure in the 70/40 range; frequently close to fainting I recently ended up in the ER as I fainted upon getting out of bed in the morning and did not come to for over 20 minutes by which time my husband had called an ambulance. It was determined by consults with both psychiatrists and internists that this episode was caused directly by the Nardil and it was imperative I begin weaning off of it as it was far too dangerous for me to be on with the way I responded physically. My heart rate was in the 40's and blood pressure when going from lying down to stand was in the 70's/40's. A month previous to this I had lowered my daily dose to 45 mg and the swelling became minimal but the other issues remained. And my mood and ability to function also decreased very noticeably. So I am beginning to slowly taper off with no idea what I will try next as i have been on just about every other drug in every conceivable combination and dosage. F 4 months
30 mg 2X day
10/23/2012
Email
 1  panic, GAD 15 mg- 3 days; no effect except felt strange on third day 30 mg- 6 days; depression (none before) , restlessness 45 mg- 2 days: depression worsen; restlessness worsen; insomnia After 45 mg, I had to taper down to 30 mg to 15 mg in just a few days because the restlessness and depression was out of control. Lyrica and Ativan helped with the anxiety. As I was tapering down, I experienced a fast heartbeat for days. When I couldn't stand it anymore, doc prescribed beta blockers to control it. Thought I could go cold turkey after two weeks and some weaning, but couldn't do it. Couldn't feel my hands and had the craziest sensations that almost drove me mad. Felt slightly better after taking 15 mg after two days of stopping. The scariest thing was the insomnia. I didn't sleep for about 5 days; 5 -10 minutes for two nights and 0 minutes for the rest. I took sleep aids, benzos, lyrica, melatonin, 25 mg Seroquel. NOTHING! I was so scared that I had developed fatal insomnia. Even if I was s F 3 weeks
15 3X day
8/28/2018
Email
 1  Major Depression Dizziness, Extremely Low Blood Pressure/Fainting, Severe Constipation w/ Anal Fissure, Anxiety Attacks, Abnormal (for me) Thougts/Writing, Weight Gain, Night Terrors so frequent and traumatic that I became sleep phobic. Feeling psychotic. My tme on this drug was the worst six months of my life. Over time the psychiatrist was prescribing so many other drugs to combat the side effects; Florinef to keep my blood pressure up and stop the fainting, Sleeping pills and anti anxiety pills so I could sleep, vitamins for my electrolytes that were tanking and finally an anti psychotic! I became more sick on this drug than without it. After passing out and not coming to this time I was rushed to the hospital. I saw a psychiatrist there who told me that my dose was too high and I was having a toxic reaction, not becoming psychotic. He took me off the drug and while I still had to deal with the depression, all the side effects vanished and I didn't need all the other drugs. I was 19 years old and on 75mg per day. F 19 6 months
75 1X day
4/9/2013
 1  Severe depression/social anxiety Other than wanting to violently kill myself, none I was so disappointed. I was so pumped to try Nardil but it gave me strong suicidal urges and I had to stop after just 8 days. :( Big downer. M 19 8 days
15 2X day
1/14/2013
Email
 5  Atypical depression To now , nothing seems bad and no side effects , even I eat what I ever want with no problems ( don't do this please ) I've atypical depression with slowed thinking process and social withdraw , I know it's early to give a feedback in 6 days only , but it seems promising and working gradually for me , I've been on more than 30 meds ( inc. Antidepressants , antipsychotics , mood stablizers , benzo , stimulants .. etc ) nothing worked realy like what nardil did in 6 days only , I still have symptomps of depression but but still early to judge this drug now but very optimistic about it because it's my last hope in life , I will update in 5 weeks ( to be full therapeutic 6 weeks ) and hope it could work for me . For inquiries I've put my email . M 20 8 days
60
2/20/2017
Email
 5  depression anorgasmia, orthostatic hypotension, insomnia, hypersomnia, myclonic jerks, constipation, farting, excessive sweating, slow metabolism worked great after 1 month. side effects almost all gone by 3rd month, except minor constipation and softer-than-before stool and excessive sweating. eating more salt relieves the embarassing sweating. complete success in recovery... combined with modafinil. without modafinil I will usually feel too "tired"/groggy and it blunts my functioning. with it, my appetite is decreased, attention increased. M 20 4 months
8/3/2008
 3  Social Phobia F 22 2 months
9/27/2004
 5  Major Depression, Suicidal Ideation postural hypotension, insomnia, extreme fatigue, daytime narcolepsy, constipation, weight gain, temporary impotence, difficulty concentrating, and much more! Thanks to this rating site and many other online message boards, I decided to try nardil after failing a couple reuptake inhibitors. I had just transferred to a university and the drug trials were profoundly ruining my life for a year. There is no other way to explain the experience other than mental torture. Nardil saved me. The only reason I had almost every side effect to extreme degrees was because I increased to 90mg/day after only 1 week at a lower dose. Had I known the intensity of side effects it would bring on at that rate, I would have been more patient in reaching my appropriate dose. Most of the side effects subsided after 6-8 weeks. M 23 6 months
30 mg 3X day
6/7/2011
 5  Depression and Anxiety None really. Better tolerated than SSRIs Great for anxiety and depression. Nothing comes close as to how effective it is, and I've tried a dozen drugs. Get on it if you've been on the SSRIs with no success! M 25 1 years
60mg 1X day
12/30/2020
 4  Bipolar disorder, PTSD insomnia, postural hypotension (passed out a few times when first starting the drug), loss of sex drive, weight gain, dry mouth. This is the only antidepressant I've ever been on that has seemed to help. Other antidepressants either didn't work at all, or made me extremely manic. It was a last resort and I'm glad I tried it because it has really helped me. The side effects are hard to deal with sometimes, but it helps and that's what counts. Also, it is very important to follow the diet because I ate the wrong food once and ended up in the ER. F 25 1 years
11/1/2006
 5  Social Anxiety and depression Low blood pressure on standing up. Sleeplessness. Better sleep when taking dose before bed. Can eat most foods on the restriction lists, but there are definite MUST NOT eat foods see link http://www.dr-bob.org/babble/20010814/msgs/75408.html Some doctors don't like prescribing it due to unjustified fear of side effects so I had a hard time getting it. Nardil is the only antidepressant/social anxiety drug that has worked for me. After going on the SSRI merri-go-round as well as lithium, tricyclics, mood stablisers, I thought there was nothing out there. Nardil pretty much started working for me after two weeks of 45mg, no suicidal thoughts since being on it, a lot more talkative and less inhibition which helps with my social function. M 26 2 months
3/12/2007
 4  Anxiety, Depression, OCD Weight gain, trouble sleeping, sweating, snoring, alternating diarrhea and constipation, flatulence. Since childhood I have taken over 20 medications for my condition, and Nardil is the best treatment. The positive changes it produces often seem lacking or insignificant, but in truth the changes are profound and mean the difference between being hospitalized and having some quality of life. M 26 11 months
120 MG 1X day
3/21/2011
 3  Major Depression Weight Gain, Constipation, Sexual Side Effects, Insomnia I have been taking Nardil for almost three years - it made me gain about 30 pounds and I have trouble sleeping (I wake up 2 - 5 times per night). However, it is the only drug (out of about 30 of the SSRI's, SNRI's, tricyclics, atypical antipsychotics, etc.) that has worked satisfactorily for me. M 26 3 years
30 Mg 3X day
2/27/2013
 2  Depression, Headaches Burning mouth syndrome, itchiness, exhaustion, restless sleep, irritability it has been helping my headaches a lot actually but im so itchy ive scratched myself until i bleed, im so tired all the time and im always irritated because of it and my mouth and nose burn all the time. i want to stay on so bad because i went from daily migraines to a few a week but these other effects are getting to me, had good results with selegiline patch but terrible rash, going to try parnate next and seeing a specialist for nerve blocks in my head F 26 14 days
15 1X day
6/22/2023
Email
 5  Depression, anxiety Constipation, sleepiness, high BP, sexual probs Brilliant drug! Nothing beats it. Works so well, makes all s/effects worth it. When you take this drug properly it creates a health euphoric feeling. Brilliant! M 27 4 years
2/15/2006
 5  Depression Slight weight gain (easily counteracted with exercise); mild fatigue (again, exercise); constipation in first couple months (eat fiber). Saved my life. When Prozac stopped working, Nardil proved to be a miracle drug! Not only did it allow me to have a normal, outgoing personality, but allowed me to date, build relationships, and live a normal life. This drug is the reason I can live like anyone else.. I can live without the fog of depression. Each day feels like a positive, new day. And yet, it doesn't dull the emotions. I still feel great music, still have strong emotions, etc... it just takes away the awful, awful depression. So sad doctors know little about this drug. If only more people knew about Nardil.. if only. M 27 2 years
60 1X day
4/21/2012
Email
 5  Depression, Social anxiety disorder None Stopped taking pristiq and started Nardil 7 days later. I didn't sleep the first night, but wasn't even tired the next day. I feel amazing and have to constantly ask the people closest to me if I seem manic because I feel so good but feel extra talkative. For the first time in my life (without benzo's) I have absolutely no social anxiety. Life just seems amazing now. I was taking Nardil last year at the same time as a strong painkiller and always looked off my face, and had postural hypotension to the point where I kept waking up in cake, on the floor etc. This time around, minus said painkiller, I am experiencing no side effects whatsoever. Unless the joy for life I have really is mania or true euphoria, in which case I welcome it. I am going to tell my doctor to stop prescribing other ad's as this is the only he should really ever use. I've tried everything and this is the only drug where I have seen a noticeable difference. It felt like waking up from a nightmare. The relief is amazing and I truly believe this medication is a godsend. I'm not even sure it has had time to even kick in but if it gets any better they will have to start calling it ecstacy. M 27 2 weeks
90mg 3X day
7/6/2011
Email
  

NARDIL  (PHENELZINE SULFATE):  Phenelzine is an antidepressant (monoamine oxidase inhibitor). This medication treats depression by restoring the balance of certain natural substances (neurotransmitters) in the brain. Phenelzine can improve your mood and feelings of well-being. Usually, this medication is used in persons who have not responded to treatment with other drugs.    (Sources: U.S. Centers for Medicare Services, FDA)

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