DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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 ADRENAL CORTICOSTEROIDS

 Type: Rx Drug

  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8


More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Acute sinus swelling. None. I went to several doctors (allergists and general practitioners) from age five to thirty-five. I could not breathe through my nose or smell anything. My nose would run constantly and I was sneezing often. I finally gave up, as no pills these doctors gave me helped at all. At age 35, I decided that I should have a regular physician, so I called a referral service. During my initial visit, the doctor asked if I had any specific problems. I told him of my situation, and he asked me if I had ever been giver Depo-Medrol or Methylprednisolone. I said that I had tried Methylprednisolone in the six-day dosage pack. He said that wouldn't work, I need an injection. I gave me a dose of Depo-Medrol, within two days, I could breathe through my nose, smell things I never had before, and I could taste food better than ever. I go in every month for an injection and never have allergy discomfort or swelling anymore. It was a Godsend. M 51 16 years
15 MG 1X M
5/24/2010
 5  both knees Osteoarthriis Total relief from shot in each knee. No side effects. I have osteoarthritis and bone spurs in both knees with severe chronic pain and inability to walk or bike without legs locking and severe pain. A shot of Depo-Medrol in each knee lets me go back to free walking (without a cane) and bicycling without 99% of the pain. F 64 15 years
40 1X AN
3/24/2017
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 4  Rheumatoid Arthritis Anxiety, hot flushes, stomach pain and nausea. ALL ARE TEMPORARY!! I have used various methods of steroids (infusions, oral, IM) and they all work great. Yes they do give you some unpleasant side effects but these are short term and what are they in comparison with extreme joint pain and stiffness?! The worst one personally experienced is anxiety. If you experience this, contact your GP and they can give you something to help. There are always drugs that can counter act the side effects so don't listen to the horror stories! Do what is best for you, don't be put off. F 20 6 years
120mg 1X AN
8/26/2015
 5  Spring season allergy Increase of libido M 51 5 years
5/4/2013
 5  SEVERE Seasonal Allergies RELIEF!!! My entire life, my seasonal allergies have been so severe, that every May I end up in the hospital. Weekly Immuno-shots didn't do anything. The drops under the tongue, nothing. Pills like Benadryl, Allegra, Claritin, etc. are like candy to me. Sprays are just as helpful as squirting water up my nose, and my inhaler just gives me anxiety. I could take them all day with no relief. My allergist decided to give me one Depo-Medrol shot once per year and my allergies are gone - boom - relief - within 3 days. F 20 5 years
5/14/2007
Email
 5  RA & Osteoarthritis Solu-Medrol have relieved my pain and swelling now for years I look forward to for my monthly shot of relief. Though it has caused me to gain weight. It is my wonder drug. After your system get use to it side effect vanishes. F 63 4 years
100 mg
1/17/2016
Email
 5  Allergies The only side effect I have ever had with Depo-Medrol is an aching in the lower back where it is injected for allergy sufferers. The aching doesn't show up until about 6 hours later when the solution begins to crystallize under the skin. This is very manageable with just some simple Tylenol, and goes away by the next day. I have never had any adverse side effects other than this with Depo-Medrol. I began taking Depo-Medrol for severe seasonal allergies. In the summers, I could barely smell anything because my nose was running constantly. My eyes were always watering and my eyes, ears and nose itched so bad from all the pollen. Allergy pills helped a little bit, but not enough to warrant paying the price for them. So my doctor suggested an injection of Depo-Medrol given just above the right cheek. The first day, I was still sneezing a little bit, but not near as bad. By the second day, I could go outside without sneezing, without itching and without my eyes watering, and most importantly, without taking allergy pills. Depo-Medrol gave me my summers back! F 21 3 years
1injection 1X O
6/8/2010
 5  Severe Allergies None. I have suffered with allergies my whole life. I have taken everything there is in order to make it through the day: Benedryl, Allegra, Claritin, Singulair, inhalers, ect. The DEPO shot is the only thing that has ever worked for me. I get one shot, once a year, for the past three years, and my symptoms are gone within 2 days. No more trips to ER. Thank you DEPO-MEDROL. F 40 3 years
? 1X AN
4/16/2012
 4  knee pain I have notice an increase of broncitis. I do not know if this is the reason, but I have loss muscle mass in my legs. But, I continue to get the shots because it helps the pain in my knees plus the pain in my back and legs. I have been getting these shots for about 3 years now. F 64 3 years
1/29/2008
Email
 4  Lupus flare I crave sweets and gain about 5 pounds every time I get this shot. That makes 25 pounds this year. Joint and muscle pain is completely gone within 24 hours of the shot. F 35 3 years
10/26/2008
 4  Knee osteoarthritis-degeneration Facial flushing; heartburn; irregular heartbeat All side effects from injection lasted only 2 days. The relief from my knee pain lasts almost 3 months. Get knees injected every 3 months for past 3 years and it is still working. Can put off knee replacement until injections no longer work. F 69 3 years
1X O
7/7/2015
 4  Severe asthma I have severe asthma and take 2 inhalers, 2 pills and a nebulizer on a daily basis to breathe. I get an 80mg shot of Depomedrol once every 30 days without the shot I end up in the ER because I can't breathe. Yes I have gained weight and get itchy at the injection site but I will take that any day over not being able to breathe. My Asthma is so severe, without the shot I feel like I have an elephant on my chest and then a panic attack because I feel I will die The shot relieves all of that for about 30 days. They need to work on the weight gain issues because breathing and fat don't go well together F 42 3 years
80mg month
1/21/2015
 1  Had some left arm sorness After 3 treatment shots and by September 2004 I had walking problems. I quit walking altogether by 2005. I began to have: vertigo, skin rashes, muscle wasting & a scooped out hole on back, daily diarrhea lasting 3 years, insomnia, now a celiac person, headaches, no bending, no stooping, no squating indian style, no sex, no pushing, no walking hardly & with a cane mostly when out and about, vision problems, holes on my skin and lasting 9 months, sores inside of anus and out, red lower legs everyday, tight skin and tight muscles, hard to move extremeties-neck, arms, hips, legs, canstant daily all over body pain, bilateral hip problems as I walk like a duck, a freezing gait, can fall, balance problem, bloating, stiff all over. SUE THEM, SUE THEM, SUE THEM. F 54 3 years
9/18/2008
 1  fibromyalgia was going to a rheumatologist for treatment of fibromyalgia. The doc came up with a concontion of 6 mg celestone, 80 mg depomedrol and called it his "cadillac" shot. He did not tell me long term usage of steroids will cause all kinds of side effects. My primary doc sent me to an endocrinologist, who send me for all kinds of tests and found out I now have an underactive thyroid and cushings syndrome, caused by the steroids. Am in the process of being weaned off them now and we'll see what happens in the future. F 69 3 years
80 mg 1X M
9/27/2011
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 5  Rheumatoid arthritis Is the only drug to get my RA under control suring pregnancy, while breastfeeding and until my other drugs kick in. If you are complaining about the side effects you obviously didnt need it to start with. F 2 years
120mg 1X M
2/21/2013
 5  Severe rash on hands and feet No side effects only relief! I've had a horrible rash almost like poison ivy/oak. Derm says it is contact dermatitis. I've gone to walk in clinics and demand a shot of Depo instead of other steroids. The rash completely goes away for approximately 45 days. After steroid wares off rash comes back. Once itches is unbearable after 2 to 3 weeks I go on the hunt for a new walk in clinic that will give me an a shot of Depo I ask for 2 ml of 40 mg and I'm good for another 2 months.Most amazing drug. I know you shouldn't use this med for long periods of time but the pros and cons I choose no rash. M 33 2 years
2ml of 40m
6/14/2016
Email
 3  Spine fracture This doctor gives epidural corticosteroids twice a month. At first I noticed I could walk better. Now, doing research, I believe that I have muscle weakness because of the drug. For instance I don't have the strength to sit up straight. Does anyone else think that twice a month epidural injections are excessive? The way corticosteroids work in our bodies makes me think that the side effects are bound to happen sooner or later. F 50 1 years
2X M
11/19/2010
Email
 1  arthritis pain in feet loss of muscle mass,sevier mood swings, sevier leg and hip pain, tendon rupture My dr. gave me this crap to releive foot pain. When I complained about leg and hip pain he up-ed my dosage and kept giving it to me. It wasnt until the tendon rupture that I started puttin 2 and 2 together. I have stopped taking the Depo 3 months ago but the hip pain is still very intense and I am having to take oxycodone several times a day to releive the pain. M 49 1 years
40mg 1X M
11/1/2010
Email
 1  contraception I would say to ANY girl or women considering this to not even think twice. I'm 21 years old and been on the injection for one year then in January 2012 I experienced extremely painful stomach pains which prevented me from walking. I now live on 30mg of codeine (which doesnt touch my pain) and diclofenick for an anti inflammatory then a tablet to prevent ulcers on my stomach. For a 21 year old girl who is obviously planning to have children then to be told you have cysts is my worst nightmare. I now have the option of halving my chances and removing an ovary if this cyst turns cancerous, put up with the pain or wait for them to shrink. I have already been told it will take me up to 5 years to conceive and it really upsets me. The worst part was that the dep website has the cheek to say "dep decreases the chance of cysts" this is not true as me and a close friend have experienced the exact same problems. STAY WELL CLEAR. DONT GET IT! & if you are experiencing any of my symptoms get to your gp asap. F 21 1 years
1X O
3/25/2012
Email
 1  Intrathecal injection I noticed after having epidural injections that I was very very prone to gastrointestinal issues. I consistently get a flu-like illness every 4-6 weeks from the time I started this as part of my pain management routine. Without fail every few weeks I would have this "flu" that joined around me ever caught. I have nurses, family, support workers etc around me daily and no one had ever caught it. Symptoms would be: *nausea (severe) has to be controlled with IV administered through peripheral IV daily, along with gravol. That is how severe the nausea had gotten). Fever 100-103 Racing heart when standing 120+bpm (I assume it would go hand in hand with my next symptom) Orthostatic intolerance- no would bottom out when standing. Was low when sitting or supine however I didn't have the same effects from being supine or sitting, compared to standing. Unable to stay hydrated. Due to vomiting. Unable to get comfortable. I would get hot and cold sweats that would change every 2 min. Way too hot and soaked in sweat so take layers off and would be freezing before I could get a heavy sweater off. No appetite whatsoever. Started off at 135lbs and I'm 5'5 female. I was getting sick very frequently around Sept 2016... and over that last year i had finally gained a healthy weight. I was 135lbs. Its now march. 3 and I am 112lbs. I was so weak from this "flu" I was unable to get out of bed. It was terrible having this every few weeks for a ye F 33 8 months
1ml-2ml
3/3/2017
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DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

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