DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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 ADRENAL CORTICOSTEROIDS

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DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  rash missed period had to start provera to restart period after depo medrol shot stopped it! had a rash took 1 week worth of steroid pills doc prescribed to get rid of when i didnt work i got depo-medrol injection, my period which is always on time was supposed to start for days later, it didnt start that month, called doc office twice, they said it couldnt be the shot that messed up my period, so went to gyno in december after i started period but it was unusually light, brown and lasted a long time, had to get on provera to regulate it again, but it did get rid of the rash so that was the only good thing from it, gyno told me it very well could have been the shot! 22 1 days
12/28/2009
 1  Frozen shoulder I received one Depo shot for frozen shoulder in Nov 2016. Approx 1 week after that I experienced heart rate up to 140, anxiety, panic attacks, 10 lb weight loss, depression and insomnia. Went to my GP who said it was not from shot, blood work was normal, she prescribed ativan, which I did not take. Starting seeing a Naturalpathic who said my adrenal function is low, even though blood work is within normal(but on low side) and symptoms probably due to shot. I am now on mega B, C and stress vitamins and take skullcap for anxiety. I am 4 months out and the lingering side effects are anxiety/depression and occas panic attacks, which my naturalpathic and I are working on. I have never had any of these before and they are quite debilitating. I feel better overall but by no means 100%. I exercise and eat healthy and all of these things help I think. Alcohol and caffeine makes symptoms worse.I am just waiting out these lingering symptoms and hope they subside in time. 57 1 days
not sure 1X O
3/15/2017
 1  Allergies I received an injection of depo medrol for bad allergies. I had told the doctor that I could not take the dose packs because of anxiety. One day after the injection, extreme fatigue,sugar dropped to 56, sweating, extreme anxiety,pins and needles in my feet. Missed a week of work just lying in bed waiting for it to go away! 49 1 days
Injection
5/16/2019
 5  both knees Osteoarthriis Total relief from shot in each knee. No side effects. I have osteoarthritis and bone spurs in both knees with severe chronic pain and inability to walk or bike without legs locking and severe pain. A shot of Depo-Medrol in each knee lets me go back to free walking (without a cane) and bicycling without 99% of the pain. F 64 15 years
40 1X AN
3/24/2017
Email
 5  knee osteoarthritis None. The drug has been a miracle for me. Did not realize how much trouble I had walking before injection. F 70
40mg 1X day
9/9/2015
 5  PMR Seronegative RA None at all. I have taken oral steroids & had the most awful side effects, so came off on a fast taper. Since having this steroid injection 7 weeks ago I feel normal again. No joint pain, sleeping properly. I've even managed to lose 19lbs since I had it. F 59 1 days
120MG
11/30/2015
 5  RA & Osteoarthritis Solu-Medrol have relieved my pain and swelling now for years I look forward to for my monthly shot of relief. Though it has caused me to gain weight. It is my wonder drug. After your system get use to it side effect vanishes. F 63 4 years
100 mg
1/17/2016
Email
 5  Sciatica or extreme lower back pain No side effects I believe I suffer from sciatica. 6 months ago this happened and a doctor told me that's what it is. It's only in my back, I don't feel any discomfort in my legs or hips. Strictly lower back. Anyways, I couldn't tell you what happened but like a light switch, yesterday, my back started in. This morning, I couldn't dress myself. Literally. Couldn't walk normally, the worst, most extreme back pain I have ever experienced. I'm a nurse for a doctor and it occurred to me that could give myself this shot. The 5 or 6 800mg ibuprofen cut nothing. Advil, did nothing, bengay, nothing. No exaggeration, not one bit of relief. So, I got to work drew up the 1 ml of depo medrol and for good measure I drew up a nice 3mg of toradol. As fast as I could, I shot myself in my right deltoid muscle. About 2 minutes later I could walk normally. My back was still tight but a good 80% of the pain was gone. It's now 645pm and I'm still very comfortable. Little tight but pain is minimal. I gave myself these shots at about 745am. F 32 1 days
1ml
6/23/2016
 5  Rheumatoid Arthritis Lack of a period, increased appetite. I've been very pleased with how well it cut down on the pain and inflammation. I was given the injection intra-muscularly and within 2-3 days, was feeling incredibly better. I haven't experienced a flare up in over a month (when I normally have one every couple weeks). F 31 1 months
10/4/2009
 5  SEVERE Seasonal Allergies RELIEF!!! My entire life, my seasonal allergies have been so severe, that every May I end up in the hospital. Weekly Immuno-shots didn't do anything. The drops under the tongue, nothing. Pills like Benadryl, Allegra, Claritin, etc. are like candy to me. Sprays are just as helpful as squirting water up my nose, and my inhaler just gives me anxiety. I could take them all day with no relief. My allergist decided to give me one Depo-Medrol shot once per year and my allergies are gone - boom - relief - within 3 days. F 20 5 years
5/14/2007
Email
 5  rhematoid arthritis tired Works great, I can walk up and down the stairs again. F 55 4 times
1/25/2009
 5  Allergies The only side effect I have ever had with Depo-Medrol is an aching in the lower back where it is injected for allergy sufferers. The aching doesn't show up until about 6 hours later when the solution begins to crystallize under the skin. This is very manageable with just some simple Tylenol, and goes away by the next day. I have never had any adverse side effects other than this with Depo-Medrol. I began taking Depo-Medrol for severe seasonal allergies. In the summers, I could barely smell anything because my nose was running constantly. My eyes were always watering and my eyes, ears and nose itched so bad from all the pollen. Allergy pills helped a little bit, but not enough to warrant paying the price for them. So my doctor suggested an injection of Depo-Medrol given just above the right cheek. The first day, I was still sneezing a little bit, but not near as bad. By the second day, I could go outside without sneezing, without itching and without my eyes watering, and most importantly, without taking allergy pills. Depo-Medrol gave me my summers back! F 21 3 years
1injection 1X O
6/8/2010
 5  knee pain This is a one time injection to the knee. Injection is painful, but the results are wonderful. The relief may last for several months possibly a year. F 58
1X day
8/1/2010
 5  severe sinus in spring/fall NONE So miserable in the fall with my allergies, I was unable to function or sleep, couldnt breathe for about 2 months before I went to the doc. Stuffy/runny nose, sneezing, blowing my nose all the time. Not a sinus infection. Got a depo medrol injection in my arm, same day - INSTANT relief. That was five days ago, still feeling great. It is an instant relief for me as I suffer from allergies year around, severe year around. I think it just works for some people, and doesn't for others, it also depends on what its given for. Every body handles different medications differently. F 23
not sure 1X AN
9/12/2011
Email
 5  Severe Allergies None. I have suffered with allergies my whole life. I have taken everything there is in order to make it through the day: Benedryl, Allegra, Claritin, Singulair, inhalers, ect. The DEPO shot is the only thing that has ever worked for me. I get one shot, once a year, for the past three years, and my symptoms are gone within 2 days. No more trips to ER. Thank you DEPO-MEDROL. F 40 3 years
? 1X AN
4/16/2012
 5  Rheumatoid arthritis Is the only drug to get my RA under control suring pregnancy, while breastfeeding and until my other drugs kick in. If you are complaining about the side effects you obviously didnt need it to start with. F 2 years
120mg 1X M
2/21/2013
 4  Rheumatoid Arthritis A single Depo-Medrol injection was prescribed by my rheumy one week ago as a "bridge" to manage pain from RA until the Methotrexate and Enbrel take affect. Took 2 days to feel any benefit from the injection, but it has helped immeasurably. At day six I experienced an anxiety attack in the middle of the night with perceived difficulty breathing. I experienced this same side effect 4 years ago while taking the pill form for several weeks due to a neck injury, so I was prepared for it. If not for the anxiety attacks, I would be very satisfied with this medication. Depending on any returning pain levels as this injection wears off, I may submit to another one to continue to hold me over until the other meds kick in. Also, found the injection to have much more efficacy over the pill form. Good luck to you who are reading this and I hope this review helps you. As a footnote, I want to also mention that I am not normally prone to anxiety attacks and have only experienced them while taking Prednisone. F 46 1 days
80 mg
7/4/2012
Email
 4  knee pain I have notice an increase of broncitis. I do not know if this is the reason, but I have loss muscle mass in my legs. But, I continue to get the shots because it helps the pain in my knees plus the pain in my back and legs. I have been getting these shots for about 3 years now. F 64 3 years
1/29/2008
Email
 4  Lupus flare I crave sweets and gain about 5 pounds every time I get this shot. That makes 25 pounds this year. Joint and muscle pain is completely gone within 24 hours of the shot. F 35 3 years
10/26/2008
 4  BURSITIS bEST RESULTS ABOUT 5 DAYS AFTER INJECTION F 56
9/20/2005
  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

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