DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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 ADRENAL CORTICOSTEROIDS

 Type: Rx Drug

  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Rheumatoid arthritis Is the only drug to get my RA under control suring pregnancy, while breastfeeding and until my other drugs kick in. If you are complaining about the side effects you obviously didnt need it to start with. F 2 years
120mg 1X M
2/21/2013
 5   M
8/3/2009
 1  pain. I recieved shot Rash 2 week then got rash week later F 1 days
40 mg
6/3/2014
Email
 1  supposed trigger point in back Update from 7.5.12 and 7.10.12 postings: side effects of pain in extremities persist as well as extreme fatigue. Also, the injection had no therapeutic effect whatsoever. I have done quite a bit of research on Depo-Medrol and corticosteroids in general since many MDs seem clueless about the side effects of the drugs they most frequently prescribe and have no interest in problem solving. For those with an indentation from soft tissue injections, find medical article "Treatment of Local, Persistent Cutaneous Atrophy Following Corticosteroid Injection with Normal Saline Infiltration" by PETER R. SHUMAKER, MD, JAGGI RAO, MD, AND MITCHEL P. GOLDMAN, MD. The article is in the following journal: Dermatol Surg 31:10:October 2005. Apparently, saline infiltration which is easy to do, works to fix the indentation (but good luck finding a doctor who has heard of this); you should be able to find the abstract for the article online and the paper at a medical school library. A good dermatologist should know about this technique or be willing to investigate it for you. This doctor is familiar with the technique and it might be worth contacting him: MELVIN A. SHIFFMAN, MD, JD Section of Surgery, Newport Specialty Hospital, Tustin, California. For other issues such as muscle weakness, extreme fatigue, nerve issues, get your adrenal glands checked by a GOOD endocrinologist. Corticosteroids are known to interfere with adrenal gland function which can result in a host of uncomfortable to debilitating symptoms. I hope this information might help someone suffering from a terrible reaction to corticosteroid injections. F 1 days
20 1X day
7/18/2012
 1  Injected in foot for pain An hour after injection, I was on floor crying in pain. I had muscle spasms in my back for days, it was horrible the worst pain I have ever had. My dr told me it had nothing to do with shot and I will strongly disagree with that! F 17 1 days
3/17/2014
Email
 1  Allergies I got my shot a little over 24 hours ago and from the front of my head to the back and all the way down is severe pain. I'm having a very very hard time moving around. The only time it wasn't as bad is when I'm laying down in a certain position. F 17 1 days
80 MG
10/25/2016
Email
 2  birth control, ovarian cysts severe mood swings, extreme fatigue, migraines, food cravings, dizziness, inability to focus, numbness of feet, decrease in libido, nausea, acne, achey joints i have only taken 1 shot, but i will not be receiving another. a few days after my 1st shot i began getting extremely mood & was ALWAYS TIRED. now, a month after my shot, i have migraines every day, crave odd foods, am constantly dizzy, and am uable to focus. i have also had a major decrease in sex-drive, experience some night time nausea, achey joints, numbness in feet, and have had an increase in acne. i was COMPLETELY UNAWARE of all the side effects of this drug and feel that i was not properly informed about it by my doctor. F 18 1 months
1X O
9/23/2010
 5  SEVERE Seasonal Allergies RELIEF!!! My entire life, my seasonal allergies have been so severe, that every May I end up in the hospital. Weekly Immuno-shots didn't do anything. The drops under the tongue, nothing. Pills like Benadryl, Allegra, Claritin, etc. are like candy to me. Sprays are just as helpful as squirting water up my nose, and my inhaler just gives me anxiety. I could take them all day with no relief. My allergist decided to give me one Depo-Medrol shot once per year and my allergies are gone - boom - relief - within 3 days. F 20 5 years
5/14/2007
Email
 4  Rheumatoid Arthritis Anxiety, hot flushes, stomach pain and nausea. ALL ARE TEMPORARY!! I have used various methods of steroids (infusions, oral, IM) and they all work great. Yes they do give you some unpleasant side effects but these are short term and what are they in comparison with extreme joint pain and stiffness?! The worst one personally experienced is anxiety. If you experience this, contact your GP and they can give you something to help. There are always drugs that can counter act the side effects so don't listen to the horror stories! Do what is best for you, don't be put off. F 20 6 years
120mg 1X AN
8/26/2015
 3  stop the cramps and the periods the side affects that I had were dizziness,mingranes,and enema.some bleeding within the time I was on the shot. I thought it was ok yet it did not work for me the way i wanted to . so i wouldnt try it again. F 20
4/27/2005
 5  Allergies The only side effect I have ever had with Depo-Medrol is an aching in the lower back where it is injected for allergy sufferers. The aching doesn't show up until about 6 hours later when the solution begins to crystallize under the skin. This is very manageable with just some simple Tylenol, and goes away by the next day. I have never had any adverse side effects other than this with Depo-Medrol. I began taking Depo-Medrol for severe seasonal allergies. In the summers, I could barely smell anything because my nose was running constantly. My eyes were always watering and my eyes, ears and nose itched so bad from all the pollen. Allergy pills helped a little bit, but not enough to warrant paying the price for them. So my doctor suggested an injection of Depo-Medrol given just above the right cheek. The first day, I was still sneezing a little bit, but not near as bad. By the second day, I could go outside without sneezing, without itching and without my eyes watering, and most importantly, without taking allergy pills. Depo-Medrol gave me my summers back! F 21 3 years
1injection 1X O
6/8/2010
 1  contraception I would say to ANY girl or women considering this to not even think twice. I'm 21 years old and been on the injection for one year then in January 2012 I experienced extremely painful stomach pains which prevented me from walking. I now live on 30mg of codeine (which doesnt touch my pain) and diclofenick for an anti inflammatory then a tablet to prevent ulcers on my stomach. For a 21 year old girl who is obviously planning to have children then to be told you have cysts is my worst nightmare. I now have the option of halving my chances and removing an ovary if this cyst turns cancerous, put up with the pain or wait for them to shrink. I have already been told it will take me up to 5 years to conceive and it really upsets me. The worst part was that the dep website has the cheek to say "dep decreases the chance of cysts" this is not true as me and a close friend have experienced the exact same problems. STAY WELL CLEAR. DONT GET IT! & if you are experiencing any of my symptoms get to your gp asap. F 21 1 years
1X O
3/25/2012
Email
 1  Hives When our daughter was in college and getting ready for her wedding she had unexplained hives. Went to doctors and the nurse gave her a kenalog injection not in the hip in case of side effect but in the arm. She had the side effect of muscle wasting at the injection site. Not good when you are about to get married and in a sleeveless dress. We visited the doctors office not to sue but to advise and work a solution out. We asked them to pay for what our insurance did not cover to have it fixed. They did, thank heavens. Our daughter had plastic surgery to repair. It fixed it and she has had no problems since. The plastic surgeon said sometimes it can recur even after surgery but it did not. That's been about 9 years ago. It was outpatient surgery. Steroid shots or Meds are Very risky. I'm sure they can help but can also hinder. Use your own judgement. We never found out the cause of her hives? Maybe nerves from upcoming wedding? Not sure. I would say be aware and proceed with extreme caution if you ever need to have an injection or need the medicine. F 21 1 days
60mg?
12/15/2015
 1  just normal form of birth control. Period for 4 weeks. Bv infection yeast infection soreness everywhere itching. Uti. Terrible mood swings. Dryness as in skin and vagina. Legs hurt and tingle. Depression. Hotflashes. Bad cramps back hurt. head hurt on and off. Stressed! Gained a lot of weight then lost it and barely eat. Crying so much. Joint pain along with bone pain. Stomach belly button area hurt. Under rub cages kinda hurt. And a feeling of getting pricked with a needle mostly in my legs and sometimes other area of the body. I went on this hoping things would be great but no they suck this is not for me or my body. I barely eat or drink water. I got a on and off Uti which i never had. I'm paranoid and have so many panic attacks everyday. Cause something new will be going on with my body. I want it out my body so bad. Some people body can take this. My best friend cool all that happened to her is she spots and sleep more. But not my sensitive body. I dont if its the shot thats doing all This but my body cant take it. I cant wait for it to be over. So i can stop going to the doctor and spending all my money on that F 21 1 months
every 3mon
1/17/2016
Email
 3  rash missed period had to start provera to restart period after depo medrol shot stopped it! had a rash took 1 week worth of steroid pills doc prescribed to get rid of when i didnt work i got depo-medrol injection, my period which is always on time was supposed to start for days later, it didnt start that month, called doc office twice, they said it couldnt be the shot that messed up my period, so went to gyno in december after i started period but it was unusually light, brown and lasted a long time, had to get on provera to regulate it again, but it did get rid of the rash so that was the only good thing from it, gyno told me it very well could have been the shot! 22 1 days
12/28/2009
 2  Pleurisy I had an allergic reaction to this medicine. I got a fever and chills from it and now I have pain in the injection site that has not gone away. It hurts really bad to touch the spot. F 22 1 days
80 ml
12/7/2012
Email
 5  severe sinus in spring/fall NONE So miserable in the fall with my allergies, I was unable to function or sleep, couldnt breathe for about 2 months before I went to the doc. Stuffy/runny nose, sneezing, blowing my nose all the time. Not a sinus infection. Got a depo medrol injection in my arm, same day - INSTANT relief. That was five days ago, still feeling great. It is an instant relief for me as I suffer from allergies year around, severe year around. I think it just works for some people, and doesn't for others, it also depends on what its given for. Every body handles different medications differently. F 23
not sure 1X AN
9/12/2011
Email
 2  poison ivy it didnt work and my rash is rapidly spreading wtf F 23 1 days
1X day
7/19/2011
 1  wrist pain Pain in my hand and arm..got worse each day. I took the shot about a week ago. And the pain is worse when I make a first with my hand. F 23 1 days
40mg
9/11/2013
 1  Allergies & Sinus pain Muscle & tendon pain, 2 Seizures I had this shot in Sept & had a seizure within a week of it. It didn't even help the allergies or sinuses! My blood pressure within 1 week was 150/129. I had another seizure last week, almost 3 months after the shot, & my blood pressure's up again. The doctor says I had a severe reaction to it. 1shot did all of this! It impaired my muscles & tendons in my legs. I still have muscle cramps @ night along w/no sleep most nights. I also have an ulcer now. I wouldn't recommend this shot to my worst enemy! I've suffered constantly since receiving it. I was a very healthy woman before this shot. Now I'm severely depressed. Worst of all, they tell me it could be a year before I get back to normal. F 23 1 days
11/29/2008
  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

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