DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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 ADRENAL CORTICOSTEROIDS

 Type: Rx Drug

  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Severe seasonal allergy Did not help at all,could not focus trying to pack for vacation(have packed for years) very difficult crazy bad dreams,confusion waking up like you where in a dream Would NEVER take this drug again they say there are no side effects with this drug, I say they are crazy should certainly have precautions before taking it there are major side effects F 77 1 days
80 1X day
8/14/2016
 2  Left knee pain Got injection in left knee. Was better while numbing was active. Now, knee is stiffer and hurts more than before shot when I walk F 73 0 days
1X day
12/16/2020
Email
 1  Knee bursitis Pain worse since receiving an injection one week ago. In addition to the severe pain, there is a burning sensation deep inside my knee and general weakness of the leg. The injection site is bruised and painful in addition to the pain within the knee itself. I would never have agreed to an injection had I known my condition could worsen. It has been seven days since I received the injection, and the pain has been severe at times. F 73 1 days
6/26/2020
 1  Pain in legs Abscesses, tremors, BMS, anxiety, weight loss, depression, skin atrophy arms and legs, still suffering 9 mos later It’s poison F 73 2 days
160 mg
11/17/2019
 1  pain Very sick raised my blood pressure very very high my heart beating very fast my stamach sollen and side and the pain was in my left not my right side a rash on my arm and my right ankle burning with my gums sollen pain this is a very bad drug and the pain i haf the shot for is not even gone Drs should not use this for people in pain makes it worse now i just heard theres a recall on this drug so why did he use it that dr is going to get sued if i do not get better and so is the manfacturer. F 72 1 days
30mg
5/3/2015
Email
 5  knee osteoarthritis None. The drug has been a miracle for me. Did not realize how much trouble I had walking before injection. F 70
40mg 1X day
9/9/2015
 1  Nerve pain in shoulder Severe anxiety, dizziness, no appetite, Muscle cramps and muscle tightness in neck and Felt like I was losing my mind Terrible side effects for 2 mths. Still have tightness on my neck and shoulder muscles Awful side effects. NEVER AGAIN Doctors never told me of effects F 70 1 days
80 mg
12/9/2019
 1  Pain in T8 spine Had Depo Me from injection in T 5/6 area for pain in T8 in Nov. By December Strange spine feeling started. By March no sleep more pain then I ever had in my life. Burning low back pain into legs, Mid back and been neck. By April without any sleep I ended up with A FIB in hospital. Never had that before either. No doctor wants to discuss Depo Metro as suspect. Big cover up. I think I am dying slowly. No one cares. poison. M 70 1 days
Not told
4/28/2019
 1  For shoulder pain Horrible anxiety headaches. Both legs cramped Muscle tightness. Depression. Now thyroid is off Horrible side effects still going on after 6 weeks I was a healthy person before Doctors don’t know this drug's bad effects! F 70 1 days
80
11/13/2019
 4  Knee osteoarthritis-degeneration Facial flushing; heartburn; irregular heartbeat All side effects from injection lasted only 2 days. The relief from my knee pain lasts almost 3 months. Get knees injected every 3 months for past 3 years and it is still working. Can put off knee replacement until injections no longer work. F 69 3 years
1X O
7/7/2015
 1  fibromyalgia was going to a rheumatologist for treatment of fibromyalgia. The doc came up with a concontion of 6 mg celestone, 80 mg depomedrol and called it his "cadillac" shot. He did not tell me long term usage of steroids will cause all kinds of side effects. My primary doc sent me to an endocrinologist, who send me for all kinds of tests and found out I now have an underactive thyroid and cushings syndrome, caused by the steroids. Am in the process of being weaned off them now and we'll see what happens in the future. F 69 3 years
80 mg 1X M
9/27/2011
Email
 1  Piriformis syndrome, sciatica Pain much worse after injection. It has been 15 days since injection and still have redness at injection site. Could not sleep for several days. Therapist I am seeing now said I am terribly inflamed. I thought this was for inflammation and not to cause it. I can only hope this horrible soreness and pain goes away. I WILL NEVER HAVE ANOTHER!!!!!!! F 68 1 times
40mg 1X day
8/24/2017
Email
 1  Arm hand and shoulder pain I HAD DEPO MEDROL ABOUT 5 YRS AGO FOR ARTHRITIC KNEES WORKED LIKE A MIRACLE...WENT BACK TWO WEEKS AGO TO HELP MUSCLE PAIN IN NECK SHOULDER ARM AND HAND IT HAS MADE ME FEEL SO ILL.I SEARCHED THIS WEB TO SEE IF OTHERS HAVE HAD SIMILAR BAD REACTIONS...PAIN IS WORSE MUSCLES EVEN MORE KNOTTED NASTY DREAMS MASSIVE SWEATING EXHAUSTED WEEPY ACHE ALL OVER THIS AM DIARRHOEA TOO I JUST WANT TO CURL UP AND WAIT FOR IT ALL TO STOP SHAKY WEAK AND VERY DISAPPOINTED NOT WITH DOC HE VERY GOOD AND I HAVE FAITH IN HIM BUT THE EFFECT THIS TIME...DISASTER Obviously different at different times NO prob ist time..this time im crying aboutit all a lot and feel really low F 67 14 days
40mg
8/21/2017
 1  Allergic asthma Mood swings. Food cravings (alcohol and chocolate), that were unheard of for me. Two weeks after treatment had cramping in all fingers, both feet, both legs and both calves for 4 nights. While swimming one day in deep end of pool, both legs. Had to be helped out of the pool; couldn't walk. EXTREME weight gain: 16 lbs in 2 weeks. It's been 2 months, and only 6 lbs have come off. I have always been a healthy, active person...and never had side effects from medications. I will adamantly reject being given this drug in the future. Treatment for asthma/bronchitis: Urgent care center 1 injection Depo-Medrol 80 1 strip pack of Prednisone F 67 1 days
80 1X day
12/4/2011
 1  inflamation from knee injury Three weeks after injection - rosacea. -- Four weeks after- mustache growth -- Five weeks after - thinning of the skin on my face (tiny blood vesssels visible all over my face) -- Weight gain - gained 15 pounds in three months - had never had this kind of weight gain ever in my life. My Dr. said "coincidence" to all the side effects. But ... In researching all this on the internet, I found numerous incidence reports of similar occurances. Contraindications to depo-medrol seem to be thyroid conditions (I a take meds for hypothyroidd.) Kidney conditions (I have only one functional kidney) Hormone replacement therapy (I take estrogen.) -- Would I take this medication again? NEVER! F 67 1 days
9/11/2007
Email
 1  bilateral sciatica At MAYO CLINIC, they found a cauda equina syndrome, peridutal fibrosis and a arachnoiditis. Bladder and bowel incontinence, paralyse legs, no more erection and lot of pain. Please look at the English documentation comming from Pfizer who claim that epidural injection should not be used. jeangodbout.ca/csst/arnaque-du-dr-marcel-morand-physiatre.html M 67
1X day
10/22/2022
Email

Patient History
 2  Severe seasonal allergy First, acute spike in blood pressure and heart rate, anxiety, difficulty sleeping (even sitting still), acid stomach, belching. Next day, alarming physical weakness, dizziness, depression. Starting that second night, heavy but unrestful sleep with unusually vivid, crazy, even revolting bad dreams (normally, I rarely even remember my dreams) with lingering gloom on waking. (Now I dread going to sleep!) Pain from hip injection much worse 3 days afterwards, despite hot baths and massaging the area; feels like my hip was hit with a sledge hammer! Depo-Medrol alleviated about 95% of my major allergy miseries in 24 hours, but then the "roller coaster" of very unpleasant side effects after that are a whole new bunch of miseries! I think next time I'll suffer through the allergy with more OTC meds rather than undergo these awful side effects again!! The doctor said this shot could give me amazing relief. Well, yes...and NO!!! M 65 1 days
80mg 1X day
8/8/2016
 2  Joint pain No side effects. No pain relief after injection. Three days after infection pain not any . Pain is worse F 65 1 days
injection
6/10/2016
 1  L5 s1 lower back and arthritic hip. My pain is much worse now than it was before I ever had the Injection I would never Have another injection of depo-medrol or Kenalog F 65 2 days
?
12/10/2015
 1  knee sprain The stiffness and soreness in my knee immediately returned. Like going back to square one. I only got the injection because I was going hiking for a week. The knee had nearly healed. A steroid shot had been recommended by another doctor for a previous sprain, and by friends who's had it. Instead of relieving the symptoms, it was like re-injuring the knee. M 65 9 days
1X AN
8/14/2015
  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

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