Drug Ratings for DEPO-MEDROL

Average Rating: 2.2 (72 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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    Charts & graphs: Reviews Summary for DEPO-MEDROL  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
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 4  Fibro, RA, OA, stenosis & sciatica Don't heal as quickly. Reduced sinus swelling, allergies better. Happened to Get shot in hip w/bursa swelling (20+yrs)- better, pain in lower back - better, pain from Fibro - less & less flares, arth pain - better & better life because of less pain, better motion & emotion! I live the life - 40yrs Fibro & back/hip pain many of u describe as side effect. I'm sorry that maybe dosage wrong or whatever reason it was a bad experience for u. I am so grateful my Dr cared enough to find something that helped me. I have to wait 30 more days, he says not good to take more than 3x's a yr, & I am counting down the days! F 56 6 months
20
9/2/2014

 1  BronchoSpasm (Asthma) I've had depo before and it never did this to me before. Extremely rapid heart beat, irregular heart beats, and fluttering heart with any movement (no endurance). Shallow breathing. Could not walk far without feeling my heart was about to burst. Could not swat a fly without my heart overreacting and going wild. Slightest emotion caused my heart to go wild. Felt like acid or fire running through my arm and neck veins. Twice I almost died. Felt like I was in the 7th circle of hell! Felt like fire, then antifreeze, running through every cell of my body with rapid heart. Muscle weakness. It has been 20 days since receiving the shot and I'm still having symptoms. Have not been able to walk through a department store without feeling like my heart can't handle it. Going to have a heart ultrasound to ensure depomedrol didn't blow my valves. Having been praying like crazy to get well. This stuff is poison! Never again!!! (He should have just given me steroids by mouth.) The labs making this stuff need to be inspected and cleaned up! F 57 1 days
80 mg 1X D
8/21/2014
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 1  pain. I recieved shot Rash 2 week then got rash week later F 1 days
40 mg
6/3/2014
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 1  Facet Joint Arthritis PANIC, ANXIETY, DEPRESSION, SKIN BURNING, HOT FLASHES, INSOMNIA THAT CAUSED WEIRD SEIZURE MOVEMENTS AFTER GOING DAYS WITHOUT SLEEP, ER VISITS, HOT FLASHES, PERIODS WENT CRAZY FOR MONTHS AND MONTHS!! NEEDED BENZO VALIUM TO KEEP FROM GOING INSANE!! I HATE BEING STUCK ON VALIUM!! Was FINE before shot!! Slept well, no anxiety before or during periods, no anxiety PERIOD!! The night of the shot I woke up with my whole body flushing..like my skin was on fire. I was BEGGING Jesus to help me. I began to have a panic attack, could not sleep, and felt like I was going to die. I suffered it out the night, got a little better, then thought drinking water would "FLUSH" the med...NOT!! I was told by family to give it a few days. I did not sleep and kept having SEVERE panic while trying to sleep. My body was jerking, felt like I was dying. After day two I went to the ER, the Doc felt really bad for me and said it WAS the steroid shot, and I would most likely feel better in a few weeks. NOPE!! In and out of a few ER's after going 3 days with no sleep each time and the anxiety was AWFUL!! Primary care doc told me to take some valium to help; it did a little but not much. She said some people have had this happen, but after a few months it goes away. Well...I am STILL suffering 1 year and 3 months later. After the first three months post injection, I HAD to find a psych dr., I have bad reactions to SSRI's and other psych meds apart from Valium...so he prescribed 5mg a day. After a week, I felt, ok so I thought I would ween off...BAD idea; symptoms came back. Tried to go back up on 5mg, but it no longer worked. Had to up to 10mg. Stayed on that for about 10 months or so, even on that dose...I had issues before and during my period with worse anxiety and s F 38 1 days
80mg 1X D
4/27/2014
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 1  Injected in foot for pain An hour after injection, I was on floor crying in pain. I had muscle spasms in my back for days, it was horrible the worst pain I have ever had. My dr told me it had nothing to do with shot and I will strongly disagree with that! F 17 1 days
3/17/2014
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 2  shouler pain torn labrum Had injections twice within a 4 month peroid. Servere cramping of all muscles. orthapedic doctor who did injections NEVER informed me of SIDE EFFECTS or AFTER CARE let alone what he was injecting! I think these injections are used very recklessly and are doing far more damage than good. After second injection ring finger has gone totally numb. Also pain in kidneys. M 43 1 days
injection
2/12/2014

 4  Inflammatory arthritis Headaches and soreness at injection site but only for a couple of days. Each dose lasts around 6 weeks each to help especially the pain and inflammation and fatigue F 37 2 months
120mg
12/31/2013
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 3  severe scalp psoroasis I had to get this injection because my scalp psoriasis was severely flared so I went to urgent care and that is when I heard of this injection. The Dr was explaining the shot to me and how it will work, he said it surpresses the immune system so I asked does that mean i m gonna get sick he said no its not as bad as it sounds so I got the shot Monday night Tuesday I woke up feeling great my head was so much better... Wednesday I woke up in the worse pain ever with strep throat fever flu symptoms... Thursday even worse than Wednesday so I went back to urgent care they said I got sick because the depo medrol surpresses ur immune system and I said I knew it was gonna happen so the gave me antibiotic injection and today is Saturday and its not as bad but it still hurts to swallow and my teeth seem sensitive hmmm kinda weird. I really don't know what was worse the psoriasis or my body feeling like I got hit by a bus... I still keep looking up as things could be worse. F 27 1 days
80mg
12/7/2013
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 1  Legg-Calve-Perthes Disease Hip pain Had injection in hip joint for pain related to childhood bone disease. It has been causing arthritis in the hip and residual pain in my back. Right after shot was limping. Lidocaine used with injection made no difference, increased pain began immediately and worsened. Can't find a comfortable position to stand, sit, or lay in. Pain is intolerable from my hip the whole way down to the middle of my calf. Muscles feel sore and achy, knee joint hurts when still or bending. At some points leg cannot bear any weight. Have tried both NSAID and narcotic pain relievers with no success. Was told this "doesn't generally happen" and clearly, from the ratings on this site and others, it does happen. Just say no!!! F 28 1 days
20mg
10/30/2013

 1  wrist pain Pain in my hand and arm..got worse each day. I took the shot about a week ago. And the pain is worse when I make a first with my hand. F 23 1 days
40mg
9/11/2013

 1  shoulder pain I was given a shot of this in my shoulder. Within 2 days i developed severe anxiety, heart palps,cramps in both legs,both arms,extreme next and upper back pain,eye twitching,ears ringing,chin and left face twitching,burning mouth and tounge,lips,weight loss, blue toes...For eight months these symptoms went on. It is now a year and my mouth still burns and face still feels odd. Countless doctors,spinal tap yielded nothing. No doctor but my dentist will admit it was the depo medrol. Very active woman who is an endurance horse rider and runner. Life was nearly shattered because of this drug! F 48 1 days
80mg
8/26/2013
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 1  Knee Pain I have taken this injection in my left knee, after taking injection within half-an hours time it was reacted, I got swelling complete knee area and sevior pain, and muscle was weaken. Now I am suffering with 10 times more pain than compared to before taking this injection, after two months also the swelling was not gone. Be aware before taking this injection. M 38 2 months
1X O
8/22/2013

 1  intramuscular injection/back pain Total body melt down and over a year later, still have side effects. Vision problems, nerve pain all over, weight loss, hair loss, digestive issues, continuous menstrual bleeding for about 8 months, the list goes on . . . seriously frightening medication. Be careful with this medication, do your homework in advance. To the angry reviewer a couple of reviews down, berating women for confusing Depo Medrol with some other drug, sounds like you're having some steroid rage issues. Yet another common side effect. F 33 1 days
40 1X D
7/1/2013
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 5  Spring season allergy Increase of libido M 51 5 years
5/4/2013

 3  Allergic reaction to antibiotics First of all, all you young women on here bashing this drug because you claim you used it for "contraception"...get off the Internet, pay attention at your practitioner's office and find out what you are REALLY putting in your body. You're so damned ignorant! Depo medrol is a corticosteroid, not a contraceptive. You women are probably on Depo-provera which is A COMPLETELY different type of drug. If you morons payed more attention to what's going on perhaps you would be in better health, rather than broadcasting your stupidity over the Internet. F 32 1 days
4/29/2013

 5  Rheumatoid arthritis Is the only drug to get my RA under control suring pregnancy, while breastfeeding and until my other drugs kick in. If you are complaining about the side effects you obviously didnt need it to start with. F 2 years
120mg 1X M
2/21/2013

 1  Thumb Tendonitis Complete numbness of thumb for 3 days, after which I lost about 60% of sensation in my WHOLE body, particularly my scalp, face, neck, teeth, butt and back. Doctor says that my symptoms have nothing to do with the injection, but the numbness spread from my thumb all over my body. It has been a week now and I am not regaining sensation. I am very nervous and hope that something wasn't seriously damaged. I can't tell if my tendonitis is better because I can't quite feel anything on my body. F 30 1 days
unsure 1X O
12/11/2012
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 1  Allergy-Poison OAK I got the shot in my hip. The next day my back started hurting. It's been three days now, I still have my Allergy and my back feels as though its being crushed. I am in so much pain! Almost constant muscle spasms in the mid section by spine and rib area. F 44 1 days
40 MG 1X D
12/10/2012
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 2  Pleurisy I had an allergic reaction to this medicine. I got a fever and chills from it and now I have pain in the injection site that has not gone away. It hurts really bad to touch the spot. F 22 1 days
80 ml
12/7/2012
Email
 1  supposed trigger point in back Update from 7.5.12, 7.10.12, 7.18.12 postings: side effects of pain in extremities persist as well as extreme fatigue and muscle weakness. Also, the injection had no therapeutic effect whatsoever. It seems there is a common, scenario - what I experienced along with many others - that makes me wonder about the competence of doctors who administer these injections: doctors not informing patients in advance about possible long-term, serious side effects; doctors being far too cavalier in administering these injections; doctors denying side effects patients experience (some patients are told that they have "anxiety issues" or it's all in their heads! - read reviews elsewhere, the level of medical incompetence is truly amazing); and doctors being completely uneducated about side effects. PLEASE, everyone who has experienced serious adverse reactions to corticosteroid injections, file a report with the FDA: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053074.htm or call the FDA at 1-800-FDA-1088 to report by telephone. I had trouble filing online and sent a hardcopy to the FDA (which was acknowledged by letter from the FDA). Lawsuits are very difficult to bring, and the only way to force responsible administration of these potent drugs is for EVERYONE who has suffered serious side effects to report to the FDA. Corticosteroid use (abuse) is now booming business for doctors and drug companies, and it seems that the administration of these drugs has become unbelievably irresponsible. MANY people are suffering from the cavalier administration of corticosteroid injections and you can help put an end to the irresponsible administration of these medications by reporting your experience to the FDA. F 44 1 days
20 mg 1X D
9/29/2012

 1  osteoarthritis in hip Increased muscle pain at injection, uncontrollable sweating, anxiety, depression and dizziness. I will never take this again - did not help much with pain and side effects are worse than before I had injection. F 44 1 times
80mg 1X O
9/28/2012
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 1  ESI for bulging disc Insomnia, muscle weakness, cramps all over, menstrual irregularities, GI problems, extreme fatigue, hair loss, nerve pain going on 6 months now since last injection. Not warned of any serious side effects when I specifically asked and docs later denied any connection between injection and side effects. Google article “Understanding Potential Complications Of Epidural Steroid Injections: Practitioners need to understand and educate their patients regarding the full scope of potential side effects that can occur when receiving epidural steroids." The article states: “Despite the indisputable rise in the number of pain interventions, little has been written about the potential side effects of administering steroids into the epidural space. In fact, many premier textbooks allocate only a couple of pages to exploring glucocorticoid mechanism of action and then only briefly mention potential side effects. This lack of understanding has led many practitioners to naïvely view steroids as benign drugs without fully comprehending the broad scope of potential side effects that can occur when steroids are injected into the epidural space . . . to understand the full scope of complications that can arise from epidural administration of glucocorticoids, it is necessary not only to understand the technical/mechanical complications that occur with needle placement, but also to grasp the role of pharmacokinetics, steroid particulate size, and, most importantly, how glucocorticoids affect nearly every organ system.” Also google 1.25.12 Bloomberg News article "Bristol-Myers Warning Ignored on Steroid Shots Tied to Deaths" F 36
80 1X D
8/14/2012

 1  supposed trigger point in back Update from 7.5.12 and 7.10.12 postings: side effects of pain in extremities persist as well as extreme fatigue. Also, the injection had no therapeutic effect whatsoever. I have done quite a bit of research on Depo-Medrol and corticosteroids in general since many MDs seem clueless about the side effects of the drugs they most frequently prescribe and have no interest in problem solving. For those with an indentation from soft tissue injections, find medical article "Treatment of Local, Persistent Cutaneous Atrophy Following Corticosteroid Injection with Normal Saline Infiltration" by PETER R. SHUMAKER, MD, JAGGI RAO, MD, AND MITCHEL P. GOLDMAN, MD. The article is in the following journal: Dermatol Surg 31:10:October 2005. Apparently, saline infiltration which is easy to do, works to fix the indentation (but good luck finding a doctor who has heard of this); you should be able to find the abstract for the article online and the paper at a medical school library. A good dermatologist should know about this technique or be willing to investigate it for you. This doctor is familiar with the technique and it might be worth contacting him: MELVIN A. SHIFFMAN, MD, JD Section of Surgery, Newport Specialty Hospital, Tustin, California. For other issues such as muscle weakness, extreme fatigue, nerve issues, get your adrenal glands checked by a GOOD endocrinologist. Corticosteroids are known to interfere with adrenal gland function which can result in a host of uncomfortable to debilitating symptoms. I hope this information might help someone suffering from a terrible reaction to corticosteroid injections. F 1 days
20 1X D
7/18/2012

 1  supposed trigger point Update from 7.5.12: all side effects persist. Found out proper dosage for depo-medrol. In addition to being in the package insert material it's posted in the July 15, 2002 issue of the American Family Physician Journal (article title "Joint and Soft Tissue Injection"): 2 to 10 mg for soft tissue and small joints. So, the 20 mg I received for one trigger point (soft tissue injection) is excessive. I was told by the doctor who injected this that I was receiving a "tiny amount" of depo-medrol, and when I later complained about side effects, I was told that the dose was a "pediatric" amount. Btw, I'm under 100 lbs. and along with horrible nerve related side-effects, lost weight because of this injection. F 44 1 days
20 mg 1X D
7/10/2012

 1  supposed trigger point in back menstrual irregularities; red face and chest; extreme insomnia; pain/tingling/numbness/weakness in extremities - arms, hands, legs, feet. Just one trigger point injection of 20 mg. depo-medrol 3 1/2 months ago resulted in numerous side effects. The menstrual irregularities, red face and chest and extreme insomnia have subsided, but the pain in arms, hands, legs and feet persists and isn't letting up at all. I was told by my doctor that this was merely a "pediatric" dose and harmless. Well, not for me and it may well not be a small dose for the purposes of one trigger point injection. Corticosteroids are very potent drugs and in my experience with both depo-medrol and kenalog (also horrible side effects) doctors tend to be incredibly cavalier in administering these meds and have a collective blind spot when it comes to side effects. F 44 1 days
20 mg 1X D
7/5/2012

 4  Rheumatoid Arthritis A single Depo-Medrol injection was prescribed by my rheumy one week ago as a "bridge" to manage pain from RA until the Methotrexate and Enbrel take affect. Took 2 days to feel any benefit from the injection, but it has helped immeasurably. At day six I experienced an anxiety attack in the middle of the night with perceived difficulty breathing. I experienced this same side effect 4 years ago while taking the pill form for several weeks due to a neck injury, so I was prepared for it. If not for the anxiety attacks, I would be very satisfied with this medication. Depending on any returning pain levels as this injection wears off, I may submit to another one to continue to hold me over until the other meds kick in. Also, found the injection to have much more efficacy over the pill form. Good luck to you who are reading this and I hope this review helps you. As a footnote, I want to also mention that I am not normally prone to anxiety attacks and have only experienced them while taking Prednisone. F 46 1 days
80 mg
7/4/2012
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 5  Severe Allergies None. I have suffered with allergies my whole life. I have taken everything there is in order to make it through the day: Benedryl, Allegra, Claritin, Singulair, inhalers, ect. The DEPO shot is the only thing that has ever worked for me. I get one shot, once a year, for the past three years, and my symptoms are gone within 2 days. No more trips to ER. Thank you DEPO-MEDROL. F 40 3 years
? 1X AN
4/16/2012
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 1  contraception I would say to ANY girl or women considering this to not even think twice. I'm 21 years old and been on the injection for one year then in January 2012 I experienced extremely painful stomach pains which prevented me from walking. I now live on 30mg of codeine (which doesnt touch my pain) and diclofenick for an anti inflammatory then a tablet to prevent ulcers on my stomach. For a 21 year old girl who is obviously planning to have children then to be told you have cysts is my worst nightmare. I now have the option of halving my chances and removing an ovary if this cyst turns cancerous, put up with the pain or wait for them to shrink. I have already been told it will take me up to 5 years to conceive and it really upsets me. The worst part was that the dep website has the cheek to say "dep decreases the chance of cysts" this is not true as me and a close friend have experienced the exact same problems. STAY WELL CLEAR. DONT GET IT! & if you are experiencing any of my symptoms get to your gp asap. F 21 1 years
1X O
3/25/2012
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 1  Allergic asthma Mood swings. Food cravings (alcohol and chocolate), that were unheard of for me. Two weeks after treatment had cramping in all fingers, both feet, both legs and both calves for 4 nights. While swimming one day in deep end of pool, both legs. Had to be helped out of the pool; couldn't walk. EXTREME weight gain: 16 lbs in 2 weeks. It's been 2 months, and only 6 lbs have come off. I have always been a healthy, active person...and never had side effects from medications. I will adamantly reject being given this drug in the future. Treatment for asthma/bronchitis: Urgent care center 1 injection Depo-Medrol 80 1 strip pack of Prednisone F 67 1 days
80 1X D
12/4/2011

 1  Seasonal allergic rhinitis Danger!! This drug gave me diabetes! I had blood glucose of 5.2 mmol always before given this shot for my allergies. Didn't help the allergies. Now two months on and the effects should have worn off, but instead it raised my blood glucose levels to 11-15mmol. Now I'll be on diabetic drugs, probably for the rest of my life and not counting the potential organ damage that goes with it. I asked the foc when he gave me the shot what side effects I can expect and he said none. What a bunch of liars! Don't care what happens to me but I'll never set foot inside another doctors office again for however long I live. Hate the whole lot of them useless money grabbing pigs! F 40 1 times
40mg/1ml
12/3/2011

 1  migrains was given by my jaw and my whole side of face went numb and that half my face wont work. its been 3 weeks since my injection and there is no improvement. now i am getting severe migrains that are worse than what i had before given this shot. and i talked to the dr about my side effects and he couldnt give me a straight answer as to if i will get feeling back in my face. i look like i had a stroke and feel everyone stares at me when i laugh. sad that the dr told me not to smile cause it looks funny... i will never recomend this to anyone! he said will take days, week or even months to see of the feeling will come back. if anyone has experienced this please feel free to let me know what happened to you. M 29 1 times
not sure 1X O
11/30/2011
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 1  fibromyalgia was going to a rheumatologist for treatment of fibromyalgia. The doc came up with a concontion of 6 mg celestone, 80 mg depomedrol and called it his "cadillac" shot. He did not tell me long term usage of steroids will cause all kinds of side effects. My primary doc sent me to an endocrinologist, who send me for all kinds of tests and found out I now have an underactive thyroid and cushings syndrome, caused by the steroids. Am in the process of being weaned off them now and we'll see what happens in the future. F 69 3 years
80 mg 1X M
9/27/2011
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 5  severe sinus in spring/fall NONE So miserable in the fall with my allergies, I was unable to function or sleep, couldnt breathe for about 2 months before I went to the doc. Stuffy/runny nose, sneezing, blowing my nose all the time. Not a sinus infection. Got a depo medrol injection in my arm, same day - INSTANT relief. That was five days ago, still feeling great. It is an instant relief for me as I suffer from allergies year around, severe year around. I think it just works for some people, and doesn't for others, it also depends on what its given for. Every body handles different medications differently. F 23
not sure 1X AN
9/12/2011
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 2  poison ivy it didnt work and my rash is rapidly spreading wtf F 23 1 days
1X D
7/19/2011

 1  An injection for degenerative disk Pain Doctor (after my severe arguing - since the last one 3 years ago made my condition permanently worse) finally got their way, I believe so they could bill medicare. My condition is being managed by pretty low does anti-inflamatories and opiates. They insisted they had to "do something" they were just not going to give out medications. So I agreed to the injection after putting them off app. 3 years, after that, the shot was 10+ pain scale wise, in addition I now have numbness in both hands but accutely in left hand baby finger and ring finger and palm. These pain doctors want to just bill the govn.. cause I am on medicare, not caring about my concerns, which came true, now I have to have a NCS and another MRI; it was bad enough before this now all this and I may be terminally damaged. Where is the regulation on these doctors that hold your needed pain meds over your head if you do not do costly procedures? I would like to sue but I am sure in the paper work I signed all my rights away. F 50 1 times
unkown 1X D
7/15/2011
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 3  Spine fracture This doctor gives epidural corticosteroids twice a month. At first I noticed I could walk better. Now, doing research, I believe that I have muscle weakness because of the drug. For instance I don't have the strength to sit up straight. Does anyone else think that twice a month epidural injections are excessive? The way corticosteroids work in our bodies makes me think that the side effects are bound to happen sooner or later. F 50 1 years
2X M
11/19/2010
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 1  arthritis pain in feet loss of muscle mass,sevier mood swings, sevier leg and hip pain, tendon rupture My dr. gave me this crap to releive foot pain. When I complained about leg and hip pain he up-ed my dosage and kept giving it to me. It wasnt until the tendon rupture that I started puttin 2 and 2 together. I have stopped taking the Depo 3 months ago but the hip pain is still very intense and I am having to take oxycodone several times a day to releive the pain. M 49 1 years
40mg 1X M
11/1/2010
Email
 2  birth control, ovarian cysts severe mood swings, extreme fatigue, migraines, food cravings, dizziness, inability to focus, numbness of feet, decrease in libido, nausea, acne, achey joints i have only taken 1 shot, but i will not be receiving another. a few days after my 1st shot i began getting extremely mood & was ALWAYS TIRED. now, a month after my shot, i have migraines every day, crave odd foods, am constantly dizzy, and am uable to focus. i have also had a major decrease in sex-drive, experience some night time nausea, achey joints, numbness in feet, and have had an increase in acne. i was COMPLETELY UNAWARE of all the side effects of this drug and feel that i was not properly informed about it by my doctor. F 18 1 months
1X O
9/23/2010

 2   Received Shhot at noon and at 6:00pm, the pain was worse that before I got the shot. Five days out, I am still in pain and cannot lift my arm over my head and put arm behind my back. Doctor told me nothing of the drug -- just that it was a steroid. F 61
80 MG 1X D
9/7/2010

 5  knee pain This is a one time injection to the knee. Injection is painful, but the results are wonderful. The relief may last for several months possibly a year. F 58
1X D
8/1/2010

 5  Allergies The only side effect I have ever had with Depo-Medrol is an aching in the lower back where it is injected for allergy sufferers. The aching doesn't show up until about 6 hours later when the solution begins to crystallize under the skin. This is very manageable with just some simple Tylenol, and goes away by the next day. I have never had any adverse side effects other than this with Depo-Medrol. I began taking Depo-Medrol for severe seasonal allergies. In the summers, I could barely smell anything because my nose was running constantly. My eyes were always watering and my eyes, ears and nose itched so bad from all the pollen. Allergy pills helped a little bit, but not enough to warrant paying the price for them. So my doctor suggested an injection of Depo-Medrol given just above the right cheek. The first day, I was still sneezing a little bit, but not near as bad. By the second day, I could go outside without sneezing, without itching and without my eyes watering, and most importantly, without taking allergy pills. Depo-Medrol gave me my summers back! F 21 3 years
1injection 1X O
6/8/2010

 5  sinusitus no side effects, only drug that ever worked. it has been two months since my first and only shot and i have not had to use any other sinus or allergy medicines and i have suffered for years. this is the only thing that has given me relief. M 54 2 months
a shot 1X AN
6/6/2010

 5  Acute sinus swelling. None. I went to several doctors (allergists and general practitioners) from age five to thirty-five. I could not breathe through my nose or smell anything. My nose would run constantly and I was sneezing often. I finally gave up, as no pills these doctors gave me helped at all. At age 35, I decided that I should have a regular physician, so I called a referral service. During my initial visit, the doctor asked if I had any specific problems. I told him of my situation, and he asked me if I had ever been giver Depo-Medrol or Methylprednisolone. I said that I had tried Methylprednisolone in the six-day dosage pack. He said that wouldn't work, I need an injection. I gave me a dose of Depo-Medrol, within two days, I could breathe through my nose, smell things I never had before, and I could taste food better than ever. I go in every month for an injection and never have allergy discomfort or swelling anymore. It was a Godsend. M 51 16 years
15 MG 1X M
5/24/2010

 2  dermatomyositis Numbness, moody, metal taste in mouth, can't sleep. ringing in ear first treatment doctor give, yet the side effects are not worth it. It doesn't cure anything just gives the insurance more time to not approve better treatments. At the end of day I am still sick. F 46 1 days
80 1X D
4/30/2010

 1   Just after an epidural with this medication in a pain clinic, I had adrenal supression and dozens of other problems, like gastric, joint and muscle pain, infections, weight gain, etc. F 50 1 times
1X D
4/27/2010

 1  injected to help with knee pain Within a few hours a severe localized pain came in. In the left knee where there's basically no cartiledge, I was waiting for an appt. with a different Orthopedic, my family Dr., injected this into the inner side of the left knee. There's a golf ball feeling there now and it's almost completely immobile. The pain is horendous compared to before and even directly after last years surgery. Being told it would help greatly I was happy to get it as 11 prior other injections failed to help. I've had 5 kids, and this is the most painful thing I've EVER endured! The migraine and shakiness is tolerable, I'm otherwise healthy other than the breakdown in the knees. The fact of my height being 6'3", he said encouraged him to give a higher dose. DO your reseach before you're poked and prodded. This pain is unmeasuarable. F 33 1 days
80mg 1X D
3/2/2010
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 3  Osterarthritis Knees Used for approx 1-1/2 years with no side effects. After having a stroke Jan. 2009, had another injection about 8 months after the stroke. Side effects were elevated blood presure and rapid heart beat. Depo-Medrol worked for the first 1-1/2 years, but after my stroke, I think that my overall "good" health outweights the side effects of this medicine. (blood presure and rapid heart beat) M 59
40 mg 4X AN
2/4/2010
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 1  spasm in neck and thoracic spine The injections caused a flare of SEVERE nerve pain and spasm in my neck and upper body that lasted almost a month, accompanied by the following side effects: flushing and burning on my face, a rash over my upper body, coated tongue, severe thirst, and heart palpitations. The spasm for which the shots ostensibly were given is worse now than it was before I had them. I am extremely angry about this, because the doctor didn't even inform me that he was going to do the shots that day, or that he planned to inject a steroid. I already knew that steroid injections are dangerous. I am worried that these injections might have caused other effects than those I'm aware of. I just hope this will stop. I will never see that doctor again. If I thought it would make any difference, I would report him to his medical board. He also prescribed more of this wretched drug, as well as an anti-seizure medication AND Prednisone. Steroids anyone? I have come to hate pain doctors. They know very well the effects these drugs have on people, and they continue anyway. F 64 1 days
1/24/2010

 3  rash missed period had to start provera to restart period after depo medrol shot stopped it! had a rash took 1 week worth of steroid pills doc prescribed to get rid of when i didnt work i got depo-medrol injection, my period which is always on time was supposed to start for days later, it didnt start that month, called doc office twice, they said it couldnt be the shot that messed up my period, so went to gyno in december after i started period but it was unusually light, brown and lasted a long time, had to get on provera to regulate it again, but it did get rid of the rash so that was the only good thing from it, gyno told me it very well could have been the shot! 22 1 days
12/28/2009

 1  Lumbar and sciatic problems Infections, near death. Had lumbar facet block injections and trigger point injections of this deadly poison; once in October, once in November of last year. In December, had extended cold/sinus infection, then acute appendicitis followed in January by emergency appendectomy(3 days in hospital), next in February came bilateral deep vein thrombosis (blood clots in legs) with bilateral pulmonary emboli (blood clots in lungs), which nearly did me in (7 days in hospital, 5 of them in Pulmonary ICU). Permanent IVC filter implant and Coumadin for life. Other than that, it really didn't help anything any better than intramuscular Celestone injections had helped. Have other problems too, but they don't matter as much. M 56 30 days
11/25/2009
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 5  Rheumatoid Arthritis Lack of a period, increased appetite. I've been very pleased with how well it cut down on the pain and inflammation. I was given the injection intra-muscularly and within 2-3 days, was feeling incredibly better. I haven't experienced a flare up in over a month (when I normally have one every couple weeks). F 31 1 months
10/4/2009

 2  Severe hip joint arthritis Had the injection yesterday and today my face is bright red and it feels like my cheeks are on fire. No relief in the hip joint yet. No one told me this could happen. Be informed before trying this. F 56 1 days
8/25/2009

 5   M
8/3/2009

 4  MUSCULAR INJURY NO SIDE AFFECTS , I HAD 5 SHOTS OF 80MG DEPO MEDROL INJECTIONS IN THE LAST MONTHS. WELL, I HAVE RECENTLY HAD 5 INJECTIONS OF 80MG DEPOMEDROL IN THE LAST SIX MONTHS ( FEB 2009- JULY 2009 ), THERE HASNT BEEEN ANY SIDE AFFECT AND THE INJECTION SEEMS TO BE A DECENT CHOICE AS IT WORKS GOOD WITH THE PAIN, BUT ALL THESE 5 INJECTIONS WERE GIVEN AT DIFFERENT SPOTS, THE INJECTION HAS NOT YET BEEN REPEATED TWICE AT THE SAME SPOT, I AM TAKING IT FOR THE REAR DELTOID AND SHOULDER INJURY DUE TO BODY BUILDING, BUT U MUST GIVE A GOOD REST OF A MONTH FOR A TOTAL RECOVERY, THATS WHAT I HAVE LEARNED, BUT THE PAIN CAN EASE DOWN WITH IN 10 DAYS. I THINKS ITS A GOOD OPTION ,BUT AGAIN NOT EVERY DRUG IS SUITABLE FOR EVERYONE, LIKE I AM ALLERGIC TO CREATINE BUT MOSTLY 95% ARNT HAVING ANY PROBLEMS WITH IT. REMEMBER, NEVER HAVE REPEATED INJECTIONS WITH IN A WEAK, AS HAVING MORE THAN 1 INJECTION IN A WEEK CAN HAVE SIDE AFFECTS, 3 OF MY SHOTS WERE GIVEN WITH A GAP OF 15 DAYS, WHICH IS A DECENT GAP FOR ANOTHER SHOT OF DEPO MEDROL, REMEBER WHEN U START NOTICING THE SIDE AFFECTS SUCH AS BLURRED VISION, DEPRESSION, NO SEX DRIVE AT ALL, TROUBLE SLEEPING, ACIDITY, THESE SIGNS MEAN NO MORE INJECTIONS FOR ATLEAST 2 MONTHS, CUZ I DID EXPERIENCE THESE COMMON SIDE AFFECTS AFTER GETTING 3 SHOTS OF 80 MG IN A PERIOD OF 45 DAYS, AFTER MY 3RD INJECTION THE COMMON SIDE AFFECTS STARTED TO APPEAR AND I STOPPED THE INJECTIONS THERE AND THEN AGAIN HAD THE 4TH INJECTION AFTER A GAP OF 4 MONTHS, AND I WAS OK AND DIDNT SEE ANY SIDE AFFECTS AFTER THE 4TH SHOT WHICH I RECIEVED AFTER 2 MONTHS GAP. M 29 6 months
7/17/2009
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 1  ALLERGIES HYPER AND SEVERE MUSCLE/JOINT PAIN ALL OVER BODY I have no relief from allergies but ended up with severe pain F 28 1 times
5/14/2009

 1  Lower back pain Anxiety, Panic attacks, suicidal, depression. Never had a problem before the shot was given to me. I would rather die than get another shot of this poison. M 41 1 days
2/12/2009

 5  rhematoid arthritis tired Works great, I can walk up and down the stairs again. F 55 4 times
1/25/2009

 1  Allergies & Sinus pain Muscle & tendon pain, 2 Seizures I had this shot in Sept & had a seizure within a week of it. It didn't even help the allergies or sinuses! My blood pressure within 1 week was 150/129. I had another seizure last week, almost 3 months after the shot, & my blood pressure's up again. The doctor says I had a severe reaction to it. 1shot did all of this! It impaired my muscles & tendons in my legs. I still have muscle cramps @ night along w/no sleep most nights. I also have an ulcer now. I wouldn't recommend this shot to my worst enemy! I've suffered constantly since receiving it. I was a very healthy woman before this shot. Now I'm severely depressed. Worst of all, they tell me it could be a year before I get back to normal. F 23 1 days
11/29/2008

 4  Lupus flare I crave sweets and gain about 5 pounds every time I get this shot. That makes 25 pounds this year. Joint and muscle pain is completely gone within 24 hours of the shot. F 35 3 years
10/26/2008

 1  Had some left arm sorness After 3 treatment shots and by September 2004 I had walking problems. I quit walking altogether by 2005. I began to have: vertigo, skin rashes, muscle wasting & a scooped out hole on back, daily diarrhea lasting 3 years, insomnia, now a celiac person, headaches, no bending, no stooping, no squating indian style, no sex, no pushing, no walking hardly & with a cane mostly when out and about, vision problems, holes on my skin and lasting 9 months, sores inside of anus and out, red lower legs everyday, tight skin and tight muscles, hard to move extremeties-neck, arms, hips, legs, canstant daily all over body pain, bilateral hip problems as I walk like a duck, a freezing gait, can fall, balance problem, bloating, stiff all over. SUE THEM, SUE THEM, SUE THEM. F 54 3 years
9/18/2008
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