There are 298 ratings for the drug: ENBREL in the Askapatient database.

The average rating for enbrel is 3.9.
Results are sorted by length of time drug was taken from longest to shortest.    
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Key to ratings for enbrel:
5-Very Satisfied: this medicine cured me or helped me a great deal.
4-Satisfied: this medicine helped.
3-Somewhat Satisfied: this medicine helped somewhat.
2-Not Satisfied: this medicine did not work to my satisfaction.
1-Dissatisfied: I would not recommend taking this medicine.

                    
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 5  ra Started taking Enbrel when it first came out in the early 90's and it was a Godsend! Before taking Enbrel I had very little energy and my fingers were starting to get deformed. I took everything that was available. After taking Enbrel I felt great immediately, less swelling & joint pain, more energy, and I do not have any disfiguration of fingers. Over the years I have developed female yeast infections and yeast in my digestive tract and mouth. I manage these by taking non-milk based acidophilas and staying away from yeast breads and eating very little bread & pasta prodcts. I also take arava along with the Enbrel and this controls my ra. I also take calcium & vitamin D as I am now of the age to get octeoarthritis. I was diagnosed when I was 12 with jra and am now 56 years and hold down a full time job and have lots of energy. I do like the 50mg autoinjector, very convenient. I understand that Enbrel is not for everyone, but it has worked wonders for me. I understand the side effects, and I have minimal brusing/itching at injection site, I inject myself on thighs and back of arms. F 56 15 years
8/16/2009

 5  RA More infections such as sinus. Not much else. This is a miracle drug in my book. The opportunity to do what others do, live a normal life. I have been on Enbrel since it came out. I was one of the first patients in GA to have access to the drug back when you had to register with the manufacturer to obtain the medication. My advancement was slowed so much it is unbelievable. When diagnosed in 1992 I was given 18 months to be in a wheel chair. I'm not, never have been. I have had several surgeries over the years and never have any issues healing. I would suggest this drug to anyone willing to go on living. It has made a difference in my life beyond any comprehension. F 51 10 years
6/16/2009

 5  Juvenile Rheumatoid Arthritis (JRA) I have been one of the lucky few who has been virtually side effect free. I have occassional injection site reactions (maybe 1 out of every 10). They are just itchy for a few days, and I barely notice them. Otherwise, I believe that Enbrel has caused a lupus like red rash on my face (tested negative for lupus). Not painful at all, responds to topical steroids for the self conscious. Biggest problem is that if you get any serious infection, you probably will have to get off the Enbrel until it goes away. Its in times like those that you really appreciate how much the medicine is doing for you I was on methotrexate and extremely high doses of NSAIDS before getting the opportunity to try enbrel. My doctor encouraged it, and I was fortunate enough to have an insurance willing to pay the massive costs. It is EXPENSIVE. Very EXPENSIVE. Might be less than some other options, but my insurance company is shelling out $1,500+/month. If other things have failed for you, please consider talking to your doctor about this kind of treatment. It has changed my life in so many ways and allows me to do things(walking almost pain free, jogging, even running with a little work in the gym first to strengthen up those muscles). M 24 10 years
5/22/2008

 5  rheumatoid arthritis none I began taking Enbrel about 10 years ago on 3rd phase testing, double blind study. I knew the first two weeks that I had the drug and not a placibo. I went into a complete remission for about 2 1/2 years. I haven't had even one flare since I started injecting Enbrel. However, I feel that it isn't working as well as the first 2 1/2 years, but I am still very happy with this drug. I feel that it has changed the course of my RA, I have only one MCP joint that has some damage. Great Drug!! F 63 10 years
7/29/2007
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 5  rheumatoid and osteo arthritis For the first six weeks, had red bump at injection site. Ten years on, I still feel tired after a shot. Have frequent heartburn, and generally feel a bit low, even though nothing's wrong. Colds are more severe, and sinus problems are frequent. I tried the pre-mixed once a week injections, but the twice a week is painless, due to having a 7.4 ph, unlike the pre-mix. This is not a perfect drug. Is there such a thing? But I would probably be dead by now if not for this. I had severe RA with high sed rate and nothing (and I tried nearly everything) had more than a slight effect. I felt better after my first two shots. Much damage had already occured, but Enbrel seems to have nearly stopped the progression. If an excess of tumor necrosis factor-a is what is going on with your arthritis, this may be the best drug for you, if you have good health insurance or are independently wealthy. Added advice-take vitamin d and c for your immune system. F 65 10 years
1/13/2010
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 5  psoriatic arthritis Absolutely none. The 50 mg. injection can be slightly painful, but I learned that this can be lessened significantly by letting the syringe warm up a bit after taking it out of the fridge. I wait 15 minutes and then inject. Also, the best place to inject is around the naval. Enough fat there to absorb the needle easily without hitting any blood vessels! This is a miracle drug. I have been on Enbrel for almost ten years, and let me tell you, it gave me back my life. I am no longer in constant pain, the bone in by finger joints has regrown and my fingers do not appear as misshapen, and I no longer need to take Celebrex or any other NSAID. The scientists at Immunex who developed this drug should be given the Noble Prize. Think about it. Kids who were in wheelchairs are now playing football. An absolute miracle drug. M 52 9.5 years
2/4/2009
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 5  ra inj site rash itching burning bruising 1st 5 yrs couldnt dress brush hair teeth barely walk 6 mo before enbrel tried celebrex methotrexate prednisone and other drugs first hardley made a dent enbrel helped after few weeks has worked great for 9 yrs do notice not as effective now back on small prednisone dose and advil everyday went off for 1 mo right back to cripple definetly worth the risk F 42 9 years
11/28/2007

 4  ankylosing spondilitis It gave me 9 wonderful years of almost complete relief. I was able to return to an active lifestyle, even engaging in high-endurance sports. But a few months ago I started having episodes of dypsnea, or difficulty breathing, a bit like asthma attacks. It appears they're caused by Enbrel, and since I stopped the injections my breathing has returned to normal. However, the AS episodes I am now experiencing are very severe, in what appears to be a form of withdrawal. I have to take prednisone to get relief, and am starting arava to see if that will work. Had I known 9 years ago that Enbrel would have this bad side effect in the end, I'm not sure I wouldn't have taken it anyway. Those years were great. But the party's over. M 52 9 years
4/18/2008

 5  RA-Myositis extreme burning at injection site. I use the 50mg prefilled syringes. As others have said, let it warm to room tempreture. I liked when they had the powder-mix before. No burning with that, and I am not bothered by needles. Injecting in your stomach can help also, as others have said. This drug has been a lifesaver for me! I have been on it over 8 years for RA and Myositis (an autoimmune muscle disease) I take this and methotrexate and it has put be in remission with very few flares. Before I was in a wheelchair, a month after starting enbrel I was walking again on my own. I do notice if I miss and injection, I get a flare! I have never had an infection in all the years I have been on it. F 44 8 years
12/20/2008

 5  psoriatic arthritus None for 8 years, then an injection site reaction with every dose. Started enbrel in 2001, woked terific till this year when arthritus came back. Dr switched me to humira 1 week ago. Will see how this does. M 55 8 years
10/29/2009

 5  PA First few times I took injections I got a severe headache. Since first taking enbrel I have been diagnoised with migraines for which I now take a migraine pill relpax which takes care of my headaches, maybe unrelated. These headaches are not very often anymore. This drug has been a life saver for me. Any side effects are minimal as to the pain relief I have from taking this WONDER DRUG! I go on & off this drug several times a year because of minor infections. After being off for a month I noticed relief in days of restarting enbrel. Thank GOD for this medication. M 43 8 years
11/29/2007

 5  Rheumatoid Arthritis RA Can't really contribute any side effects to Enbrel. I do have increased sinus infections and urinary tract infections as well as weight gain, but this may or may not be from Enbrel. Could just be my compromised screwy immune system or few other factors. Luckily, i have never had injection site reactions, or any other immediate noticable issues. Enbrel was my lifesaver. I have been taking it for over 8 years. I have extremely high levels of RA, Felty's Syndrome (hyper spleen-low platletts) and also have several nodules that appear and disappear over time. Sometimes, the nodules (usually appearing on elbows-feet-toes, and upper chest muscle area) are injected by DR with cortizone shot to help ease pain and decrease the size. Had tried Methotrexate in past-did NOT work for me. Now on CellCept with Enbrel (50mg 1x week, and Celebrex and Hydroxychloroquine. This "cocktail" really seems to work for me. I also take Prednisone as needed for really extreme flare-ups. I almost always stick to stomach (around navel) for my injections...arms and legs bruise and hurt too much for my liking. Will notice a slight "burning sensation" every once in a while from medicine when injected, but find..if i inject slowly, it helps process. Never had injection site rash, or itching. I have had to periodically stop taking Enbrel for F 40 8 years
10/27/2008

 5  RA Difficulty fighting infections, especially lung related illnesses. Had a staph infection that scared me and my doc. Be very aware of any infections. Your immune system is extremely compromised. Great drug. Has the potential of making life enjoyable again. At $200/injection (25mg twice a week) can be cost prohibitive. It has possible side effects, but what doesn't. M 61 8 years
2/3/2010

 5  RA As far as I am concerned I have had no side effects. Oh I get bloody noses but that is when the air is dry, or I get numbness, but that is because I use the coumputer mouse too much. I get a cold once a year, but I did before Enbrel, so nothing new there. It has been the best thing and has kept my joints from degenerating and has allowed me to continue working. I am almost 61 and came down with RA during menopause, so about 13-15 years ago. Every day I can walk or work and I thank Enbrel for that. F 61 8 years
50mg 1X W
2/12/2010
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 5  Ankylosing spondilitis None other than a slightly smaller bank balance. My rating for this medication is only when taken in conjunction with methotrexate. It rates only about a 2 when taken alone. This medication made all the difference for me. Instead of constant flare ups I now only get maybe four or five a month. I also have only had one bout of irisitis (inflammation of the colored part of the eye) since taking it whereas I used to get it at least once a month. M 38 8 years
1/10/2006
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 5  Psoriasis and Psoriatic Arthritis Weight gain, Headaches, Fevers, Sweats & Chills, Bruising & Bleeding, light headed & Dizziness, Many mild infections. Mild numbing & tingling (Note more from the arthritis than the Enbrel. You'll be able to tell diffrance. If you have numbing or tingling with joint kinks,stiffness,and/or swelling. It's the arthritis. If it's with out flare up symptoms it may be the Embrel.) But over all my side effects are nothing compared to my symptoms without Enbrel. Though Embrel has not cured me and never will.(At this time our disorders are not curable. But they are treatable.) Embrel has helped a great deal in slowing the progression. My Psoriasis is almost clear. Still have a few mild spots of Plaque. but nowhere as bad as before. My Psoriatic Arthritis is much more manageable and flare ups are fewer & shorter with Enbrel. I've had to stop and start Enbrel many times over the past 9yrs.(For mild infections and once for a year for insurance.) And I can feel and see the major differance with and without. At 36 and only a year off the Enbrel I was completely disabled. The most simple of daily task became a challenge. And many like getting out of bed. Bathing and dressing required constant assistance to do. It was the scariest time of my life. But being back on Enbrel I'm still able to work a very physical job in a factory. Take care of myself and family. Not them having to take care of my basic needs. So even with all the side effects. Enbrel has been a wonder Drug for me. F 38 8 years
1/3/2010
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 4  Rheumatoid Arthritis & Psoriasis I have used it since I was 12, about 8 years. I attempted to use the "new" Enbrel, the one you only have to give yourself one injection for, and it burned horribly. I now use the older version. It was tough to get over the initial fear of giving myself shots at a young age. But it really does work...as long as you take them regularly. F 20 8 years
11/4/2006
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 5  Psoriatic Arthritis I was fairly crippled in the morning before I started Enbrel. I now have a normal life, very active, but still have some joint pain in my hands. I recently had a toenail removed (thick psoriasis nail) and had to stop Enbrel because of repeated infections and anti-biotics during the healing process. I have stopped taking enbrel for almost three weeks and have started feeling very run down but no added joint pain yet. It has been a blessing - I have traveled to Europe twice, I roller blade 3 times a week, work out with weights, and going hiking in the mountains. M 57 7 years
50 mg 1X W
3/16/2010

 5  Psoriatic arthritis Slight sore throat at times, headaches at first. Headaches have since subsided I am writing for those who experience pain using the pre-filled syringe. (I had no pain with medicine we had to mix ourselves). But I also had pain with the premixed syringes. I called the company about it. The nurse recommended that I ice my injection site (in my case, my leg) for about 15 minutes before I inject, and that I take the medicine out of the fridge 30 minutes before I inject so that it's at room temperature by the time I do so. This made an enormous difference - there is still some pain associated with the injection, but not much. Enbrel has given me enormous relief from disabling joint pain and some relief from psoriasis. F 56 7 years
6/24/2009

 5  psoriatic arthritis none effect treatment for my arthritis and also improved my relatively minor psoriasis problems. M 6 years
10/25/2008

 5  Psoriatic Arthritis small bump at inject site sometimes(like the Enbrel is just sitting there) miracle. when I can't use it due to severe cold or infection, the old extreme pain returns. Vicodin helps a bit but limits my ability to drive/work. God Bless scientists/researchers for their discovery M 49 6 years
12/14/2007

 5  Ankylosing Spondylitis As time goes on, chronic fatigue syndrome. I do take high dose narcotics in conjunction(7yrs). Enbrel SAVED MY LIFE TOO! Symptoms started when I was 12y/o; diagnosed when I was 27y/o. I was on the threshold of doing something "BAD", then I i finally got the Dx & Enbrel. As previous comments, it only took 1-2days to show effectiveness!! I just can't do anything "real" physical anymore! BUT NOW...I get cellulitis once a yr and have to be hospitalized. My lymphnodes seem to stay swollen on my neck and head at all times, though at different degrees. Any "nick" or cuts don't heal like they used to. I'm scared that I may develop lymphatic cancer! However...I will gladly battle the cancer over the pain that I had been suffering from my AS. M 33 5.5 years
50mg 1X W
8/28/2010
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 5  Mixed Connective Tissue Disease After 5 years of 100% relief, am now getting serious infections and will need to get off drug (regrettably). This is a known side effect. These infections can even be life threatening. Gave me a normal life after years of rheumatoid arthritis, severe, joint pains with no relief from other meds, except large doses of prednisone M 72 5 years
10/24/2005

 5  Rheumatoid arthritis no side effects i can be sure of injections are no fun...take two shots once a week instead of the twice a week plan. seems to work almost as well. has really helped with my quality of life. worry about the day i won't have health insurance - this is not an affordable drug. Also, travelling can be a drag. if the stuff gets warm it's no good. i just double dose the week before i go and the first week back. F 43 5 years
11/11/2005

 5  RA To the person who mentioned the very painful injection I also tried the 50mg injection....had already been using the 25mn 2x a week and my doctor thought the 50mg would be more convenient. I couldn't believe how painful the 50mg injection was....absolutely dreaded the shot....called my doctor and went back to the 25mg 2x week in the abdomen.....ALMOST NO PAIN!!!! F 45 5 years
9/15/2008

 5  RA Little or no side effects! I do have slight brusing at the injection site. However, this last only a day or two. I do get at least two colds a year...which includes sinus. I'm not sure that is due to Enbrel. I have been taking Enbrel since 2005....was diagnosis with RA in 2001 and had severe pain on a daily basis. Enbrel is a Godsend for me...I take one 50mg a week! I now spring out of bed with no pain and climb the 10 steps to my bathroom and get ready for work. Climbing the stairs is my morning exercise...it makes me feel great, as a few years back I had difficulty climbing stairs. I'm able to wear heels again and this does wonders for my Psyche. I do have a question for anyone out there...has anyone experienced canker sore...I have had one for about 1 year now and nothing seems to work at getting rid of it! I should also note that I'm Diabetic and I also take Plaquenil and Levothyrox. Many individuals have written about "being tired" that is a side effect of RA as well....I don't feel I'm tired more than usual. F 47 5 years
10/3/2009
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 5  RA Possibly low immune but live in an area where sinus trouble is very common. No other negative effects. Have had RA since 17yrs. Enbrel has been great for me...no more flare ups since beginning treatment. Felt relief with 1 week. Also, HIGHLY recommend RA people to follow a High-protein, low carb diet and exercise. My RA is VERY affected by my diet...currently down to one 25mg shot a week in the abdomen area (no bruising & no pain) F 44 5 years
4/20/2008

 5  Rheumatoid Arthritis Repeated sinus infections which led to surgery, mild flu-like symptoms (tiredness mostly) a day or so after giving myself the shot. I'm also suffering from migraines quite frequently now. Before Enbrel, I had maybe 2 migraines in my entire life. Now they're common. I take Imitrex and Naproxen to offset the repeated migraines & other headaches. Muscle twitches and facial tingling. It's marvelous in handling my severe arthritis. Without it, I'd either still be on methotrexate and steroids or in a wheelchair. I can definitely tell when I've missed a shot as the joint pain returns. Most of the time, I go around joint-pain free. Despite the side-effects I'm experiencing, I'd recommend it to people with moderate to severe arthritis. F 42 5 years
4/17/2008

 5  for Rheumatoid Arthritis RASH ON FACE...FIRST AT CHIN AREA...THEN SPREAD AFTER HAVING MY BABY TO FACE NEAR NOSE AREAS AND FOREHEAD..LOOKS LIKE ROSACEA AND ARE BUMPY WITH ITCH AND CLEAR LIQUID, CAUSES FLAKY SKIN AND REALLY DRY...ENBREL HELPS ME DO MY DAILY LIVING BUT I AM SCARED THE RASH WILL GET WORSE...NOW IT HAS SPREAD TO MY LEFT HAND ON TOP OF THE KNUCKLES...MY SINUSES ARE SEVERE NOW...I CAN'T EVEN BREATHE, HAVE TRIED ALL KINDS OF ANTIBIOTICS AND STILL THE SAME...I HAVE A COLD LIKE SYMPTOM WITH "OLD MAN" SOUNDING COUGH (SOUNDS GROSS BUT THIS IS WORSE), TOO MUCH MUCOUS DRAINAGE IN THE THROAT/NOSE AREAS...I BELIEVE ENBREL HAS CAUSED THIS... I WANT TO STOP IT AND DOCTORS SAID I SHOULD NOT... I'M SCARED TO CONTINUE TREATMENT..ALSO SLOW HEALING WOUNDS AND SORENESS OF HEAD AREAS AND OVERALL SKIN SORENESS... F 31 5 years
3/11/2009

 5  Severe Plaque Psoriasis Tired and Slightly Depressed. Weight Gain. This is a great drug. I am willing to risk the side effects in order to stay clear of my psoriasis (my body was 85% covered). I would happily sacrifice years off my life in order to have quality years while alive. This is what Enbrel has provided for me....quality of life. No blood on my sheets or shirts. No itching. No pain. No embarrassment. Shorts in the summer. No one stares. I can wear black shirts again. Simply amazing. M 38 5 years
12/13/2009
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 4  Plaque Psoriasis Outbreak of guttate psoriasis in the last three months. Have stopped injecting Enbrel but still dealing with the same psoriais which my derm says is not an unusual side effect after using Enbrel for this length of time. Not sure which is worse, the plaque or guttate psoriasis. Enbrel worked quite well until this episode took place. Plaque psoriasis has not worsened since stopping Enbrel, only the guttate. M 67 5 years
8/20/2008
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 4  Psoriatic Arthritis and Psoriasis The local site reactions went away after a month of treatment. What has plagued me and I was not sure until after I discontinued use about a month ago was premature ejaculation. Two physicians have denied this was a side effect but its onset coincided with Enbrel therapy and the resolution with discontinuing Enbrel. The Enbrel did not work for my psoriasis and therefore my derm recommended Humira. My rhum prescribed Humira upon my request and my problem went away. With regard to treating the symptoms of arthritis the Enbrel was awesome. I had not felt so good in 15 years. I had been treated with Ansaids and methotrexate for years without such good results. Enbrel was liberating, absolutely no more pain and a positive side effect for a while was euphoria which was reported by my physician. I know people for whom it works very well in treating psoriasis unfortunately I was not one of them. The other side effects of these biological drugs do bother me however but obviously not badly enough that I would discontinue taking them at this point. Hope this helps folks. If any of you experience a similar side effect please post. Cheers! M 43 5 years
4/2/2008

 1  psoriasis lymphoma, congestive heart failure For me this was a miracle drug. And now it has changed my health and well being for life. F 47 5 years
3/31/2009
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 5  Rhuematoid Arthritis I'm wondering if going into deep depression causing attempted suicides could be a possible side effect because this has happened to me and doctors can't see why. I also get bruising on the injection site and I get headaches alot and never used to. Other than that Enbrel has been fantastic! F 15 4 years
8/11/2008
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 5  Psoriasis (0) side effects from 50mg weekly injections. Been on this stuff for over 4 years and am 97% clear. No illnesses during that time, maybe a couple lethargic days that may or may not have been related to meds. 27 years of P and have tried it all. This really works for me. M 53 4 years
2/19/2009
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 5  Psoriatic Arthritis I have been taking Enbrel for almost 4 years and have had no adverse reactions. I have been dealing with Psoriatic Arthritis for almost 20 years. Most of that time I was treated with varying doses of methotrexate and extensive use of ibuprofen. The methotrexate seemed to lose it's effectiveness in 2004 and I experienced some severe arthritic symptoms of swelling, stiffness and aching joints. My doctor prescribed Enbrel and it has worked so well, I frequently forget to give myself my shots. It is working for me. I play golf about 4 times per week usually walking with my 3 wheel push cart. I also play and coach soccer. without Enbrel none of this would be possible. M 56 4 years
4/18/2008

 5  psoriatic arthritis Only a very occasional headache, nothing else I have a mild form of this disease. About 15 years ago I was in to running. I had to stop because of neck pain that I was developing. I endured gradual and increasing neck pain for 10 years. When I started taking Enbrel about 4 years ago, my neck pain stopped within 48 hours of the 1st injection and has not returned! M 49 4 years
8/19/2009
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 5  RA Not healing as fast from small cuts I was on Remicade for one year and it almost killed me. On that drug I lost 50 pounds, tired all of the time and just did not care about anything. I was rated with the highest RA count you can almost have. With enbrel I am a new person. My weight is back to normal, I can work outside without constant pain. I also have a 7 year old daughter. I missed her early years of not being able to play with her due to the pain. With Enbrel I can do anything. Taking the 50 mg shot once a week is no problem. Never-ever had any pain in the stomach area or the legs. If you have RA please ask your Dr. about this drug. Make sure you have insurance and it is covered as it costs about $1,600 for four shots. M 53 4 years
8/27/2009

 5  RA Injection site reaction; intense pain with 50 mg injection. Switched to twice weekly 25 mg injections and no problems thereafter. A wonder drug for me. However, it lost effectiveness after about 4 years. F 39 4 years
4/28/2009

 5  psoratic arthritis If i get a head cold, or flu it lasts for 7 days and hits me hard. I started enbrel with such terrible pain in my joints. It took 3 days and it was gone. One 50ml shot a week. Its the best, but expensive. I haven't had to deal with the pain in my fingers and toes ever since I started taking enbrel. One small prick a week aint nothin. M 28 4 years
1/2/2007

 5  rheumatoid arthritis occasional spots on trunk of body Enbrel has transformed by life. I was in severe pain, now this has been considerably reduced. F 53 4 years
50mg 1X W
3/5/2010

 5  Rheumatoid Arthritis No side effects at all This drug completely cancelled my severe RA - it has slowly improved my already previously deformed joints as well. Fantastic and hard to believe, but true! Now I have been off it for a year and living in total misery, feeling suicidal every day. My hands are useless and I can hardly walk. I only stopped taking Enbrel because of some other patients mentioning cancer in the on-line forums like this one... Now thinking of starting this medication again, bacause I want to LIVE! F 36 4 years
50 1X W
5/30/2010
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 4  Psoriasis and Psoriatic Arthritis Initially some injection site reactions. Used to give myself the 25 mg shot sitting up. First time I switched to the 50, I passed out cold with the needle still in my leg! Nothing serious, so now I always have to give myself the shot lying down and that is fine. Does great things for my psoriasis, less great for the PA. And I have had recurring yeast infections for two years and I think the Enbrel is the culprit. Not sure of that though. F 34 4 years
1/28/2007

 4  RA Painful injection Like many people, I switched from a powder and diluent you had to mix yourself to a prefilled 50mg syringe. I find the prefilled injection very painful to administer, whereas the old method hardly hurt at all. I have been told that the pain is caused by a preservative in the mixture. I wish I could go back to the old method. I didn't mind having to mix it myself and it didn't take long. I can understand that the drug company were probable trying to make life easier, but if it's not broken..... don't fix it. F 27 4 years
5/5/2009

 4  RA Constant colds, meaning I have to leave off injections until infection has passed (and get antibiotic or cortisone injections from GP, as body can't fight anything any more) Scared about swine flu, given how Enbrel emasculates the immune system. Has anyone read any reports or recommendations in this context? - apart from this fear, I am just so grateful that - after five years of trying unsuccessful alternatives - my Spanish doctors here put me onto Enbrel - and although there is a general prescription charge for other drugs, this is FREE! F 58 4 years
8/18/2009
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 4  RA I am frequently bothered with sinus pain, followed by nausea & throwing up..I can expect to loose a couple days when this happens.I see others have problems also.. any solutions?? Enbrel has been life changing for me. I see in other comments that you didn't inject Enbrel until the sinus issue passed.Was this by order of your Dr.or did you find that it helped on your own? Over all it has been great,just wish I could get past the sinus thing! F 63 4 years
12/6/2008
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 4  psoriatic arthritis, psoriasis fatigue, headaches, pain in shoulders (possibly from injections) helped me a lot. arthritis was severe - completely gone F 32 4 years
1/11/2010

 5  RA No side effects enbrel gave me my life back. Within days I could make a fist, joint swelling slowly disappeared, joint pain almost all gone, only a few flare ups in 3.5 years. I was able to get on with my life. F 56 3.5 years
5/4/2009

 5  Psoriatic Arthritis Some pain with injection. Chills and fatigue if I miss a dose. LOVE IT! (when taken with the MTX) Worked almost immediately (a week or two) to resolve the crippling joint pain and swelling. The new once weekly is easier to do since it's all premeasured and mixed- but BOY does it sting! F 34 3.5 years
5/22/2006

 5  psoriatic arthritis none I have been taking enbrel 1 shot per week for 3 years and I love it! I hate giving myself the shot but it is better than the alternative. I had sausage fingers the week I started the first injection and within days they were almost normal. Has not really helped my psorasis F 36 3 years
5/24/2006

 5  psoriasis and psoriatic arthritis a couple of colds that lasted longer than usual and a chronic skin fungal infection. I feel my quality of life is vastly improved. Psoriasis much decreased and arthritis pain very mild. F 50 3 years
50 mg 2X W
6/24/2010

 5  gutate psoriasis/ psoriatic arthrit Have had chronic sinus infections that are difficult to clear (many rounds of antibiotics). Also, seem to contract many more colds/upper respitatory infections that last much longer than usual. Enbrel has completely cleared my skin. I have had sever gutate psoriasis since puberty and now have freedom from that. If a few extra colds are the price, then I can deal with it. F 43 3 years
2/21/2007

 5  Rheumatoid Arthritis Sinus infections, an itchy hive-like reaction at the injection site lastly a few hours or less, bruising at the inj site. Enbrel was wonderful while it lasted. Sadly it only worked for two years then it's effectivness slowly dropped off over the course of the third year - until it did nothing at all. Great two years though! Definitely worth a try, even if you're afraid of needles like me! F 38 3 years
2/23/2007

 5  psoriatic arthritis + psoriasis I quell injection site stings by icing site before and after injecting. Enbrel is a life-saver for me. At 100mg/wk, it retards disease process & inflammation, & restores my pre-illness energy level, concentration, alertness. Unfortunately, HMO will not cover 100mg/wk past 1st 3 mos. for plaque psoriasis. So I must do with 50mg/wk which retards disease/inflammation, but stops short of fully restoring pre-illness function. Few Drs know enough about biologics or about prescribing them to include them in treatment choices for patient relief of certain debilitating conditions. Of Drs who know of & prescribe biologics, few apprise themselves of insurance protocols for expensive drugs, so fail their patients by leaving them, already handicapped by illness, to deal alone with coverage intricacies. Benign neglect is not patient care. While the longterm effects, if any, of using Enbrel beyond 7 or 8 years are unknown, many patients need many more doctors to know about biologics and how to prescribe them. F 56 3 years
5/14/2007

 5  Psoriasis I have not experienced any side effects from Enbrel. I would say it effectively treated about 90%-95% of my psoriasis. I am very pleased with the drug. I have been taking Ebrel for about 3 years. I feel very fortunate that Enbrel is available. I could not see myself go through another treatment with Soriatane. M 47 3 years
11/3/2008
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 5  psoriasic athritis no side effects .A little pain once a week ...it really works I use the enbrel for three years and my life changed from the third week M 41 3 years
6/23/2009
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 5  RA It's like my immune system becomes a screen door with every little bug or virus flying right in. I have not been able to stay on Enbrel for a sustained amount of time because you have to go off it when you get an infection and I am ALWAYS getting infections. And if you end up with the flu, it's like a truck ran over you. F 43 3 years
12/15/2008

 5  rheumatoid arthritis yeast infection in mouth - felt like pieces of skin growing inside my mouth - flaked off easily. Simple remedy was prescription tablets to suck on. rheumatologist thought it was due to imbalance of natural bacteria in mouth, probably due to enbrel. Am now experiencing burning in chest that's not responding to antacids. Family doc says dyspepsia and reflux can be side effects of enbrel, but rheumatologist never told me that. Enbrel has been a miracle drug for me, gave me my life back. Side effects so far have been manageable and minor compared to RA. I take the 25 mg shot 2x a week, zero pain and I actually only take it about 1 a week which holds me most of the time. When it flares up a little I go back to 2x a week for a couple weeks. F 51 3 years
3/13/2009

 5  RA I am in my early thirties and have been on Enbrel for two years and within a couple of weeks it completely resolved my RA and gave me my life back . I went off it for a year and a half to have a baby. Three months after I went back on it, I developed severe headaches and nausea for a couple of days, assumed it was migraine. Got progressively worse and developed a small rash on tummy-in short I had developed shingles which had progressed to Viral Meningitis. After hospitalisation for a month with anti viral treatment , I was fine again. I was reluctant to go back on the medication but had no choice due to deterioration of RA-. Despite the severity of the side effect- I am happily back on Enbrel-meningitis is curable, joint damage and deformity is not- I am taking my chances... F 34 3 years
2/5/2009

 4  Plaque psorasis Have been taking enbrel for nearly 3 years, find it has kept posoriasis at bay. Have just started getting large sores on one leg very weepy and sore hope it is not the start of ulcerated leg. Anyone else experienced this? F 51 3 years
12/28/2008

 4  Sero-neg. RA and arthrosis Not sure if from Enbrel, but: increased fatigue, blurred vision, digestive problems, bloated abdomen, weight gain despite no change in diet. 50 once week, find it hard to administer and feel dizzy afterwards (cancel any Thursday appointments on principle now)but no rash at inj site. Scared as have had TB in the past; now almost constantly suffering from cold infections but doc said keep shooting as long as no high temperature Took a while to notice any difference (but final diagnosis had also taken around 3 years, so fairly advanced by then) but it seems to have solved the RA almost completely; arthrosis remains, hands semi-crippled. Taken with MTX and NSAIDs. Has changed my life, but aware that the price for that may be high in terms of serious infections F 58 3 years
1/6/2009
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 4  RA persistent sinus problems been using for nearly 3 years.took about 2 weeks to work and was amazing.before enbrel i was in constant pain and felt horrendous fatigue.i feel the effects sre beginning to wear off although my doctor doesnt agree.i am now starting to get pain again. I fear the day it stops working altogether. F 43 3 years
9/21/2008

 4  RA Slight stinging while injecting...I do my injections in my stomach and haven't had any rashes etc... In the last year, though, I've experienced severe fatigue, depression and no energy. Wondering if lengthening out the time between injections would help that??? It's been great for my RA. I have occasional aches in my hands and SI joint during storms/weather changes but other than that I feel tons better....when I'm not sleeping from being so tired F 39 3 years
9/25/2008
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 4  PA I had a couple of times my injection site "bubble up" and i could barely get the last of the 50 mg into my subQ skin layer. when i took my first shot of enbrel i could feel it overnight that it took away the pain and some of the swelling. i was actually able to clean the kitchen for the first time in a year.It took the docters about a year and a half to figure out what was actually wrong with me.after a couple of months of not knowing what i was dealing with i was in severe pain and could barely get around.this drug has helped me take control over my life again, the only thing is that it has not really helped my psoriasis i still have some on my scalp and behind the ear. F 19 3 years
11/15/2007
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 4  Ankylosing Spondylitis Tired and flu-like symptoms often Worked great for my back pain, but the longer I take it, the more side effects I seem to be experiencing. Has this happened to anyone else? F 22 3 years
2/29/2008
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 4  psoriatic arthritis I've had a cold for much longer than I should. And have noticed this every time I get a minor cold. When i cut my ankle in a bathroom accident, it took about 5 months to heal completely. It got infected, I was on antibiotics, it oozed, and it disturbed my psoriasis. (A dermatologist was finally able to heal it completely.) Most non-arthristis doctors don't know enough about this drug. But overall, it's been great at treating my aching finger and knee joints. I'm trying to weigh the pros and cons. M 42 3 years
1/4/2007

 1  RA Headaches, dizziness, nose bleed, night sweats, chills, stomach pain, redness at the injection site, rashes, bruising, trouble with breathing, numbness in the hands, nerve damage in the left hand and arm. It helped me with RA but the side effects are dangerous. OT I have developed stomach pain, CT was all ok. Doctors cant figure it out and its getting worse. Has anyone else has same problem with Enbrel? M 61 3 years
50 mg 1X W
3/27/2010
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 5  Arthritis It works great. Took about a month to kick in. M 55 2.5 years
10/4/2005

 4  Inflammatory Arthritis Weight gain, depression, injection side pain F 42 2.5 years
2/24/2009

 3  psoriatic arthropathy spasms, twitches, lots of headaches became clustered, weakness,major sinus trouble, major weight gain, more lethargic everyday, feelings of emptyness no motivation, loss of sex drive, major mood swings, irritable all time, eyesight became weaker, high blood pressure. when i started enbrel i was amazed at how fast it worked an the pain relief i got was great also my psoriasis dissapeared an i thought that on its own was worth it. then the side effects came, at the start it was the general rashes, mild headaches,sinus trouble an some quite serious chest infections, these all became more an more frequent an i got the others added to the list too. i can only assume that my body became intolerant to the drug. i gained 2 stone(28lbs) in 2 years which wasn good yet i was more active than id ever been i was looking after myself more an didn feel that my diet had changed. i could no longer fit into any of my clothes an the side effects have became unbearable i would be given more drugs then to counter act the side effects until finally ive gave up an came off enbrel. i felt that i was always feeling ill an i was becoming quite down in the dumps about it so ive took myself off it. im due to go an see my rheumy an explain all this the next visit but im off it 8weeks an ive lost inches and am able to fit back into my last set of clothes now. i feel good about myself although my psoriasis has returned i dont care im going to treat it the old fashioned way an im back to feelin stiff, but i feel normal again an i think this is the wasy to go for me at this min. alot of the spasms an twitches an eyesight decline sparked the rhemy to send me to a nuerologist because they suspected this may all come from my nervous system, but the consultant said he F 39 2.5 years
50mg 1X W
8/10/2010
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 1  PA Took for 6 months in '03-'04. Stopped due to insurance and the symptoms returned 5 times worse (only had it in first joint of fingers then came back to affect all finger and thumb joints as well as feet). I began taking again since July of 2007. On Nov. 27, 2009 I went to the emergency room for breathing problems and was diagnosed with congestive heart failure, ejection fraction of 20%, and needed a pace maker. Other than that, my health is perfect. Doctors suspect Enbrel. I cannot believe I am considered disbled at 46. M 46 2.5 years
12/30/2009

 5  Psoriatic Arthritis None This drug has enhanced my life. I am very active I have had this condition for 16 years. M 43 2 years
11/6/2006

 5  rheumatoid arthritis none Works better than humira, which semi worked, still had regualr achy pain from RA, skin crawling, etc. F 53 2 years
50mg 1X W
6/10/2010

 5  Psoriatic arthritis Injection sight reactions...fairly large, 3 inch red itchy whelps, last 4 days or so and pain at the injection site. Like many before me have said it gave me my life back. At the time of my diagnoses, I could barely walk around my home and forget getting up stairs! I was depressed and had no hope of continuing my career in education. After the first injection I was able to go for a walk within 4 days with out being in incredible pain. Since then I have ran two half marathons (13.1), exercising regular, playing softball and best of all teaching! I don't know where I would be without it. Sadly I have to stop taking Enbrel due to it not treating my irithis I developed this year. I've just started Remicade and hope it works as well as the Enbrel has. F 27 2 years
50 1X W
5/20/2010
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 5  Rheumatiod Arthritis Some injection site itching. Perhaps increased severity of sinus infections. Took 6 weeks to take effect, and when it did, it relieved 90% of symptoms. It is not a miracle drug..still get tired easily, and do not have former strength, but before Enbrel, I couldn't even turn the key to start my truck, and had difficulty in slipping a credit card in and out of a gas pump. I can now resume controlling a shopping cart with one hand, so it has worked well, even with time-outs for back and hip surgery. Previously, I had a terrible reaction to methotrexate [and it did work for 2 months from the original dose, but on trying it again, it worked not at all]. Enbrel let me get off Prednisone entirely. I hope it keeps working. Medicare part D helps a bunch, but I go through the donut hole in late February to mid March M 77 2 years
10/28/2007
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 5  RA injection site hive - take benadryl at night and Tagamet during the day What a lifesaver. It started working within a week and my rheum says she would never know I had RA now. I was/am fearful of the lymphoma issue. However my 27 yr old sis is fighting Hodgkins and she's never taken a biologic and has no risk factors other than our sketchy DNA. I really believe it's the disease that causes cancer and not the drugs. I even stayed on Enbrel while pregnant and my son is 7 months and ahead of all his developmental milestones. Thank you to Amgen Wyeth for giving me my life back! F 37 2 years
2/10/2009

 5  Psoriatic Arthritis Tired, sleepy, lathargic at times. I have been rotating arms in my once a week shot - I stopped shooting in the leg. I have never had an injection site rash or swelling. Pain is totally gone. Miracle drug, take a shot and your pain goes away! Just had a small amount of psorisis on my forehead and behind my ears - those didn't clear up with the shot but I put stuff on it. M 36 2 years
7/26/2008

 5  psoriasis, psoriatic arthritis Slight headache for the first couple weeks, but no side effects since. I do experience a slight flu like weakness pain all over which is controlled with pain meds. I dont know if this is from the drug or the arthritis itself. A miracle drug for me. Virually took away 95% of psoriasis. Could hardly walk on sore ankles at times before taking drug. I can lead a somewhat normal lifestyle now. M 54 2 years
1/1/2009
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 5  Psoriasis Have had no side affects. Have plaque psoriasis and when taking embrel twice a week for the first 3 months, it cleared my psoriasis. Have been taking Enbrel on and off for two years now and it works for me, but then my doctor has taken me off of it because he is concern of possible effect if taking a long period of time. M 48 2 years
8/26/2009

 5  Psoriatic arthritis Fatigue, some headaches, sinus congestion, maybe some weight gain, winter flu has been much more severe. Is very effective for me. Went off Enbrel for a few months and symptoms returned,but went back on and had almost immediate improvement (2 days). M 47 2 years
10/23/2009

 4  PA I have found that my respiratory infections have taken longer to clear up. Now when I feel like I am getting sick I will stop taking the Enbrel until I am completely better. I have noticed that my weight has increased and that despite continual exercise I feel heavier than I usally am (usually thin). I wonder how this affects bloating -- something I have noticed that I experience more of. M 44 2 years
9/7/2009

 4  Juvenile Rheumatoid Arthritis I take it once every other week instead of once weekly. I haven't noticed any side effects. I am taking birth control and have noticed moderate mood changes, but I can't be sure this is from the birth control or from the enbrel. I am going to ask my doctor. F 29 2 years
5/13/2009

 4  rhuematoid artritis I would have a runny nose most of the time,and tired every day I find enbrel 50mg and metrotrexate have given me a good quality of life ive been taken enbrel now for 2 years. F 40 2 years
5/28/2009
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 4  psoriatic arthritis + psoriasis I have trouble waking up. Seem to be tired all the time. I also seem to be depressed and irritable since injections started. The 50mg once a week do hurt but worth the pain. no infection at the injection site(leg). I have had 2 needles not retract after injection. M 22 2 years
11/24/2008
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 4  Psoriasis Injection site irritation and burning as injected. Occasional bruising. Initially the dose was every 4 days. It took 6 months before an improvement was seen. Very slow. After the first year the dose was reduced to every 5 days. Continue to see improvements after 2 1/2 years. Using topical creams much less these days. Feet are really the only part where the psoriasis is difficult to treat. F 52 2 years
8/13/2008

 4  rheumatoid arthritis Enbrel was wonderful for the first 2 years but it has now started to wear off so will be trying it with Methotrexate..Injection site rash but that was the only side effect. Felt like a real person again. F 46 2 years
4/3/2007

 3  RA headache with nausia and sweating, usually several days after missing a dose, or after vigourous exercise. At first only occasional, but gradually these sick head aches became more frequent. The headaches were so unpleasant that I stopped taking Enbrel for several months. Then RA flared up badly, and I started Enbrel again. I have a sick headache as I type this, and am vowing never to take Enbrel again. Headache and sick feeling is really unpleasant. Enbrel does work VERY well for my RA, however. F 52 2 years
9/10/2007

 3  RA Two areas of fungus on hips (not at injection point) and a horribly itchy rash on my back and scalp. Currently giving myself 50mg shot weekly and taking 5mg Prednisone daily. I cannot take Methotrexate because it drives my liver enzymes high. Enbrel seemed to work at first, but I have developed hand deformity and cannot open things. One day, I could not start my car. Plus, I've had to stop Enbrel from time to time because of infection F 62 2 years
11/29/2007

 3  RA for 25 years painful injection, slight bruising, staff infection I took enbrel for 2 years with very good results until I got a staff infection which settled in 2 of my thoractic vertebrae. Spent 10 days in the hospital, the first few days in severe pain,many rounds of drugs, blood tests, MRI's. Then spent 2 months wearing a brace from my waist to my chin, and a continuous antibiotic IV for 2 months. We believe the staff infection started from a small cut on my finger, but not sure. I already had degenerative disc disease before all this, now I am on social security disability.Enbrel worked great while it worked but suppressing your immune system has it's risks. I'll never take it again. Now taking methotrexate and celebrex. M 59 2 years
5/6/2008
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 3  Psoriatic arthritis/psoriasis Tired constantly, lethargic, weight gain (a lot) no energy, constant yeast infections. I never realized that I was having any side effects from Enbrel other than being tired. I had to have foot surgery and my surgeon made me stop the drug, I began to diet and exercise to help with the PA symptons as there was no way to stay on pain killers to help with the pain from the PA. I have never felt better, being off this drug has allowed me to control my PA in a more healthy way. I also feel that it was causing fungal infections within my body, this causes so many other problems. And I do believe this caused my weight gain, 40lbs over the 2 1/2 years I was on the drug. I was finally able to loose weight when I quit taking Enbrel, that never happened before. Yes, in the beginning is was great...but to what sacrifice!! Trust in your body, I suggest looking up and staying with anti-inflammatory foods, the right foods can help you control arthritis!!! And you would be surprised what foods can help or hurt your body.....get off the drugs, be healthy from the inside. F 44 2 years
12/27/2008
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 1  psoriatic arthritis I have recently been diagnosed with MS after taking Enbrel for about 2 years. After many MRI scans and doctors visits, it seems that it is very likely that Enbrel brought about the MS. I was once a believer that the benefits outweighed the risks, but that was before being diagnosed with an disease such as MS that may land me in a wheelchair. DO NOT take this drug. F 35 2 years
9/7/2009

 1  Juvenile Rheumatoid Arthritis Did not have any immediate side affects when I took this. I am 17 now and I now have Leukemia. Enbrel has been highly linked to cancer in kids under 18. I am 17 years old and was diagnosed with APML on March 13th of this year. Do not take this drug for anything ever. F 17 2 years
8/6/2009

 4  PA and Psoriasis Fatigue, shooting pain on the arm of injection site at the time of injection (even when at room temp), buzzing in ears, increased infections and severity of infections. This as well as for others has been a life safer. It worked fantastic for the first couple of months and then a switch in my insurance company had me off my medicine for 3 months. When I was back on, the injections did not work the same. I was increased from 25 mg a week to 50 mg, since I begin to feel the need for more medicine within about 5 days. 50 mg made me lethargic and I developed serious infections. I now take 25 mg within 7-10 days. My psoriasis is controlled, but has not cleared on my scalp, behind the ears, & my elbows. I was diagnosed with PA early and but on Enbrel early on. F 28 1.5 years
7/7/2007

 4  AS Very sleepy a day or so after injection, but fine after that. Recently noticing that my extremities go to sleep quickly after minutes of sitting or just putting my arm on the back of the couch (weird) not sure if related to drug or not. Keeping up with flu shots has kept flu and colds away. This has greatly improved my quality of life, over the last year and a half. I pray it continues to work as well as it does. M 37 1.5 years
50mg 1X W
2/9/2010
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 3  plaque psoriasis stings at injection site, a general bogged down feeling for a couple days afterwards but not every week. I have had psoriasis since I was 20. I probably have it on 10-15% of my body with the worst being my scalp and finger nails. I notice when my finger nails are really bad and I am in a meeting or socializing in a group people notice my finger nails right away. I know this because they automatically start looking/biting and picking at their nails. I CANT STAND PEOPLE DOING THIS!!!! Enbrel has suppressed elbow, scalp, and knee patches but it completely cleared my finger nails in 4-5 weeks (had to grow out). I love it for this very fact but hate it for what I know it may be able to do to you in the long run. I don't want to die from lymphoma, or never recover from severe influenza. I know if I use this stuff forever this will be the case. I only use it when my nails start getting really bad. I'll do a month on and then quit for 4 months. Seems to be working out alright like this. I also use clobetasol proprianate ( a topical ointment) in conjuction with enbrel on all my elbow, knee, buttocks patches and I can almost get it completely clear for a few weeks before the lack of enbrel use regularly makes it start to come back. M 30 1.5 years
50mg 1X W
8/19/2010
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 3  ankylosing spondilitis Hi all~ N.B.: I have always taken this drug with a Cox 2 inhibitor or anti-inflammatory daily. Burning at site of injection, even with sureclick autoinjector, but tolerable. Tired after injection but felt much better the next day. Dry mouth after abt. one year of use at 50 mg/weekly. Lately, I have experienced nausea and sweats, mostly during the night. Discontinued the COX-2 inhibitor, thinking this was the cause of the nausea. Two weeks later, taking double dose of Nexium and a liquid antacid. Took my weekly shot last night and whoa, was extremely nauseous the whole night, despite all the Nexium and antacids. Either the problem is the Enrel itself or something else is going on. I found Enbrel to be quite effective but only when combined with a Cox 2 inhibitor or an anti-inflammatory (naprolen). When taking the two together, my spine was much more flexible and my joints generally felt much better. My neck, shoulder and TMJ jointa are very painful now that I'm off the other meds. Depressing, this stuff, isn't it? F 55 1.5 years
4/10/2008

 5  Psoriasis No side effects at all for the year I was on it. Slight weight gain...but I don't know if it was related. My psoriasis cleared up completely...from Scalp, arms, legs, torso and about 50% on my nails. My dermatologist recommended I stop after 1 yr of twice weekly injections to see if it would stay clear. Well I have been off it for 4 months and my scalp is back to where it was...but the rest had yet to come back. Since I have stopped injecting the Enbrel I've had recurring veginal infections (and have never had any issues "down there" in my life). I'm sure its a side effect...but why would I get them now...only after stopping the medication? Anyone else have this problem? So now I wanna get back on it...but am weary of the damage it's done even after getting off the medication. F 26 1 years
3/4/2009
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 4   Caution:After on it 9 months. Dizzy,memory problems, feet tingling, shaky hands, blurred vision, weak muscles. Doctors denied Enbrel as reason; restarting prooved they were wrong. On Enbrel for aboug 6 months when I noticed that 36 hrs later I was having Dizzy, blurred eyes problems. 3 months later I had major problems and was bed ridden; doctors at first thought Ms because of the Enbrel; Then decided no. So after I healed 3 months later I restarted it because they didn't believe it was the Enbrel. By the 5th injection my systems were coming back stronger. I have discontinued it. Advice: Listen to yourself; sometimes you just know. F 48 1 years
2/26/2009
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 4  RA Itchy rash at the injection site after injection. But, more concerning, I noticed that the day after my first injection, my breathing capability went downhill and has stayed that way more than a year later. While Enbrel helped reduce pain and swelling, I'm concerned about possible lung damage. My doctor hears nothing wrong, but I'm easily winded. Also tired, lethargic, and weight gain. Instead of weekly injections, I went to monthly injections as a sort of maintenance program and this seemed to help increase energy. Currently off the drug, but thinking of starting up again. F 56 1 years
11/6/2008

 4  AS I have experienced no side effects to enbrel.Taking it now for a year.Occasional brusing around injection site which is not the drugs fault. Prior to taking enbrel I couldnt even turn over in bed without severe pain.I was like an old man.My life has been transformed by enbrel and I am not exaggerating.Of course I am concerned about the long term effects but live for today and be happy. M 44 1 years
8/14/2009


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