ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Moderate Plaque Psoriasis I developed a serious staph G infection in my knee. My blood pressure dropped to 80/40 in the doctor's office, and for a few minutes I was so sick I thought I was dying. I came around in a few minutes, and was rushed by ambulance to the hospital, and put on IV antibiotics for 2 days until the infection cleared up. Not positive it was caused by Enbrel, but i would say likely. Cleared the psoriasis up a bit in spots, but unless it overtakes my body (currently 5 - 10% body psoriasis), I think it is too severe a gamble for me. Good luck. M 58 1 years
not sure 2X W
1/12/2014
 3  Plaque Psoriasis & Arthritis None, except for slight burning when I accidentally hit a blood vessel during injection. Once had a slight rash at injection site on thigh. I have also experienced a little dry mouth on occasion. My pain and swelling has reduced significantly, but the plaque psoriasis on my legs, feet and scalp has not cleared up as expected. In fact, my feet and legs are slightly worse, as I have now developed pustular psoriasis on those areas as well as the plaque. The plaque on my scalp seems to have decreased somewhat, but not as much as I expected. Overall, I'm not as happy as I anticipated I would be after waiting 8 months for my insurance to approve my use of the drug. F 50 4 months
50 MG 1X W
12/19/2013
 1  Psoriatic arthritis Very first day enbrel came on market my doctor called to get the injection because methotrexate wasn't working tried both pill and needle it was making me nauseated Enbrel worked good at beginning but short time after started getting infections. I was on and off for a few years until 2010 I got a serious infection that almost cost me my life all organs shut down I was on a respiratory life support with a trac. I keep getting pnomenia in and out hospital getting trac changed. I can't talk walk only dignity I have left feed myself. I can't believe a drug that's suppose to help make life easier ruined mine. But I wanted to feel good be able to go out to work pain free but now I rather suffer a little pain then of taken enbrel F 55 10 years
25 mg
12/8/2013
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 1  Rheumatoid arthritis Serious injection site reaction. Was very hopeful that enbrel would work. But I only felt worse. Joints became more swollen, more pain. Had to stop after 5 weeks. F 64 5 weeks
50 mg 1X W
11/25/2013
 1  ra I got sepsis from enbrel on May 12 2013. The ER gave me 12 hours to die or live. 103 temp and unconscious for 2 days. In fall of 2012 I asked to be taken off Enbrel & was told no. I had an arthritis nodule on my right wrist that got infected with white cells (sepsis). had two surgeries & 17 staples & 3 weeks of infusion antibiotics & 3 weeks of oral antibiotics. not able to take my arthritis meds and the only thing that is helping with RA pain is 20 mg prednisone. READ very carefully the medical insert that comes with your enbrel and ask yourself is it worth the risk. Sepsis is very painful and very dangerous. Not many people survive sepsis and I am very lucky! F 60 6 years
50 mg 1X W
11/11/2013
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 4  ra Fungal lung infection have caught every bug that comes along it helped my joints but do not like all the side effects M 65 10 years
50mg
11/5/2013
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 4  Severe plaque Psoriasis entire body Although it worked it almost cost me my life. I had flu like symtoms and became so dehydrated from vomiting my husband finally made me go to ER. It also decreases appetite. I just made it to ER and as soon as a nurse started an IV for fluids to be given and draw blood, my heart stopped. I refused to go to ER for two days because I thought I had the flu. I was then life flighted to a trauma heart center. I have been psoriasis free for 4 years now. Patients should be seen by their private medical Dr at least twice a month even if they are feeling well. The dermatologist who administered my injections never told me I should be closely monitored by my personal physician. PLEASE post these symptoms on your web site and tv advertising. It should be known. Thank you F 40 3 months
100my 2X M
10/12/2013
 5  plaque psoriasis & psoriatic arthri Very occasional injection site reaction. F 30 10 years
50 mg
9/29/2013
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 5  Rheumatoid arthritis since 1995 I have a history of headaches and have had a few doozies in the last 3 weeks but I'm not sure if its me or the Enbrel. My BP was up to 170/105 and that's unusual so I'm getting that checked out but I have had NO JOINT PAIN since I started 3 weeks ago. I can straighten my fingers which I haven't been able to do for a year. I can work out with pretty heavy weights and my grip strength is like a normal person plus no swelling the next day. I'm really excited that I've had such success and pray it will be the new norm. F 43 3 weeks
30mg
8/12/2013
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 3  Juvenile arthritis I've seen a positive improvement in my joints after taking enbrel, but this week after my fifth injection I got a horrible face rash that worsens when I go in the sun. F 14 5 weeks
7/7/2013
 1  rhumatoid arthritis After being prescribed Embrel, i decided not to take it due to all the bad side affects that i heard about. I chose to go on a trial drug test , i have been on it for 3 years now and it is to be realeased on the market here in Australia at the end of the year. USA has been realeased already. its fantastic. Blocked stuffy nose at night ( but this could also be age related ) is my only side affect. I am now on no prednisolone at all... was 20mg a day. have lost weight , no swelling or sore joints . and feel fantastic. I hope it works for everyone how its worked for me. Its also in the form of a tablet. F 49
1X day
6/18/2013
 5  Psoriasis Bruising at injection site - but only occasionally If I were reading some of the reviews without my own experience, I would be scared to death. However, this has changed my life, and as long as it works, I'll keep taking it. As for painful injection and welts, the stomach is the best to avoid this - also letting the medicine warm up to room temparture helps. I have had no problems with this medication (except for occasional bruising). The biggest pain is having to get blood work done every three months, but I'm glad my doctor stays on top of it to ensure I'm pulled off of Enbrel if there's any chance it's causing other problems. F 36 6 years
50 1X W
6/14/2013
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 5  RA no side effects This is the Best medication for my arthritis. I have tried many others one but no one has helped me so much. M 71 7 years
1X W
5/25/2013
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 1  Rheumatoid Arthritis MAJOR insomnia. Loss of appetite day after injection. Bloating. More colds/infections. Dry mouth. Major injection site reaction. Looked like a bug bite on week 2 but on week 3 looked like a bee sting reaction. 2 inch by 2 inch red inflamed area. Stayed for almost a week. One month after quitting injections muscles still have knots in them from the injection. (Quad muscles). Immediately stopped this drug. I have just started a gluten and dairy free diet to see if this will have any impact before I opt to try any more powerful Meds. God bless to all my fellow sufferers out there. F 38 3 weeks
5/14/2013
 3  RA None Worked for 5 years. At times I could go 5 weeks between shots, then take an injection when I felt stiffness coming on. Then it stopped working. M 81 5 years
50mg 1X W
5/6/2013
 1  psoriasis arthritis Gain weight, easyly caching ilnesses, Cough, Weak body, Pale skin. I used Enbrel after i tried steroids and MTX. after 2 years i tried Enbrel it worked and reduced my joint pains but side effects were crucialy reduced my daily life. then i stopped treatment M 2 years
25mg 2X W
5/4/2013
 5  RA No side effects. Completely changed my life--I would be in a wheelchair by now w/o Enbrel. Was initially on MTX, plaquenil and minocycline but couldn't get above the lowest dose of MTX because of bone marrow suppression. Went on Enbrel as soon as it came out and experienced relief within days. What little pain I experienced with regular inj was nothing compared to RA pain....have no pain at all with autoject. Some side effects that people experience would occur with RA regardless of being on Enbrel--I know this from being a healthcare professional myself. You just have to weigh the pros and cons and decide if the benefit outweighs the risk. F 48 14 years
50MG 1X W
4/16/2013
 4  anklosing spodylitis(AS) & colitis Burning at injection site for 20-30 seconds durring/after injection. I was diagnosed with ulcerative colitis at 15 yrs old. Sacroilitis kicked in at 20, and I've been on vicodin ever since (9 years). I walk with a severe limp because of the pain half of the time, and experience stiffness for about a hour & a half after waking everyday. My spine has straightened from c8-c1, and causes intense tension headaches that wake me in the middle of the night. My head would hurt so bad that I would use icepacks, pain killers, muscle relaxors and nothing would change the level of the pain. The only thing that helpful was anti-inflammatories, but I can not take those because my ulcerative colitis would immediately flare up and my colon would bleed heavily. My headaches usually last 1-4 weeks, moderate back pain is present 50 percent of the time, severe sacroilitis that leaves me bed bound is once 1-3 days every 3-4 months. I am taking Enbrel injections once a week, and I am looking forward to my 3rd shot in a few days! Since my first injection I have not limped, my back pain is barely noticeable, and my stiffness in the morning is down to 20-30 minutes. My headaches are are a 1 out of 10, and my neck's muscle tension is at a 2 out of 10. This improvement is amazing, and I hope that it will last. I am worried about side effects like weight gain, hair loss, and infections. F 29 2 weeks
50 MG 1X W
4/15/2013
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 4  Psoriatic and Rheumatoid Arthritis After being on this drug for many years I developed a mysterious and severe staph infection in my cervical spine, threatening paralysis. Doctors couldn't figure out what was going on and did emergency surgery and biopsy. Several disc fusions and months on antibiotic fusions, doctors took me off Enbrel, thinking lowered immunity led to staph infection. Was off for two years and tried methotrexate. That was horrible and eventually went back to Enbrel. Seem to get every cold, virus, and sinus infection possible. Resistant to antibiotics. Began this drug many years ago off label before approved. Even with serious complications, being on Enbrel has allowed me to live relatively pain free and function almost normally. Didn't really control the psoriasis though. F 58 15 years
50mg 1X W
3/19/2013
 3  psoriatic arthritis and psoriasis malignant kidney tumor; loss of teeth due to infection M 52 10 years
50 mg 1X W
2/20/2013

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