ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Arthritis Serious infection after 120 days, comma. Almost death. But, they were a great 90 pain free days. I am in so much pain without enbrel but,if I got a serious infection once will it happen again? F 57 1 days
30
1/19/2016
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 5  psoriatic arthritis none Has me pain free and playing hockey and golf. I have even taken up guitar M 56 3 years
50 mg 1X W
1/17/2016
 4  RA Burning with injections. I prefer prefilled syringes versus the auto inject. I can control how fast to give it to myself. I do get erythema at the injection sites for about 3-4 days after injection. I'm also on Methotrexate injection weekly. I started about 3 wks ago with a headache to my forehead, cheeks radiating into my jaws and posterior neck. These start about 2 days after the injection and lasts about 2-3 days. I notice they start in the evening and cause severe nausea. They kind of knock me down for a while. I have a history of migraine headaches, so I initially thought it was the headaches coming back again. After a lot of research , I now realize it's a side effect of the Enbrel. I have experienced moderate relief of the pain to my hands and feet.☺ It used to hurt so bad to step on the floor in the mornings, or to make a fist or hold a pen. Those symptoms have improved and a intermittent. I'm thankful for the relief I've experienced. I'm praying the headaches will subside over time and I can continue on Enbrel. I am disappointed with the minimal information on the Amgen website regarding headaches. They don't inform on the severity of these and how debilitating they can be. I'm hanging unto the Enbrel train though, until theres a need to change. Remember: research, inquire, study and learn all you can about your illness. Be sure the info is Reputable!! Arming yourself with knowledge keeps you in control of your body. Prayers and hugs to all.👍💝 F 47 7 weeks
50mg 1X W
1/11/2016
 5  RA seronegative arthritis No side effects at all.Just great results. ... I took RA at in my late 20s. Before that I was very fit and played rugby and boxed at a high level.I had no problems at all with arthritis. When I took RA It was very aggressive and the doctor said it was the worst case he had seen.it got that bad that every single joint was swollen on my body.Avert hard time in my life and if your reading this with arthritis u will understand. Once I was put on enbrel.I was clear of any swollen joints within a week. I am feeling good now and have ran a few half marathons and weight train 3-4 days a week. Ps Don't let arthritis beat you M 35 4 years
50mg weekl
1/10/2016
 3  Ankylosing Spondyloathritis 1 days
50mg a wl
1/8/2016
 4  Ra Severe headaches Initially it seemed to be a wonder drug and worked great for my many symptoms. With the past few injections I have experienced severe headaches. F 50 5 months
50mg
1/6/2016
 5  psorasis high triygiserides works on my skin like none other ever did M 60 5 years
50ml 1X W
12/31/2015
 3  Rheumatoid arthritis Brain fog extreme tiredness pain rash on my leg sometimes it leaves me feeling in a box the world is going on and I'm in a box horrible feeling may not continue I see my doctor on Monday I want to see if there's another alternative I feel at this point my blood test showed everything is normal even my arthritis is normal I don't feel normal F 67 6 months
50
12/26/2015
 1  psoriatic arthritis I really thought I was going to die. I only did 2 injections. My overall condition got worse. I developed rashes that a dermatologist is still trying to figure out. I developed weakness that I never had. I was so sick overall. This is going on two months and I'm wondering if I will ever recover from this. I know these drugs may work for some people but I wish I would have never tried this. One injection of Humira had a similar effect. I have decided that I will not take anything that supresses the immune system ever again including steroids. I will do as much as I can naturally. This was very dangerous for me. I believe I may have had an underlying condition and Enbrel made it worse by lowering immunity. I am interested if anyone knows how to recover from this. M 46 2 weeks
50mg
11/27/2015
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 3  RA My Rheumy doubled the Enbrel doze to 100mg weekly because of pain, then l developed severe heart burn ( too long a story to get into but missed 6 weeks of work) which resulted in long term issue. Now must take life long low dose old fashioned anti depressant for heartburn issue. Recently caught severe virus with flu like symptoms, severe cough, bronchitis then sinus infection, my first. I assume with a weakened and supressed immune system if I continue taking Enbrel I'll continue to get sick and just can not afford this pattern. Not sure I want to go back on Enbrel. Not sure what to do. F 63 3 years
50mg 1X W
11/25/2015
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 5  as None Joint pain, tendon pain neck pain back pain, cardiac issues spasms in neck and back all much improved due to embark and methotrexate wish I had started years ago when first went undiagnosed still have fatigue but pain and immobility going awaHi bey geeatly M 63 1 years
11/23/2015
 4  JRA After the 1st mouth of injections my condition improve so much so that I could begin playing sports again, with out much pain. There was one side effect that persisted with treatment (sever headaches) in the mornings after injection night prior. M 16 6 months
11/4/2015
 4  rheumatoid arthritis Serious cough and dry reaching or vomiting nearly every day. Severe stomach pain when eating or just after eating. Red, itchy rash on lower legs and spreading. Cortisone cream does not help it at all. Have had pneumonia several times a year and also prone to catching any infection going around. Enbrel worked from the very first injection. Absolutely fantastic BUT now experiencing severe side effects. Have had all necessary tests done to find out why coughing and vomiting and all have come back clear so can only blame it on the Enbrel. Not nice to be out to dinner, one cough and then vomiting. F 68 2 years
50 mg 1X W
10/28/2015
 5  Rheumatoid Arthritis No side effects because I use the powder vials 25mg 2x/wk because they don't burn. The powder and diluent has to be mixed prior to injection. It's a very fine needle injection. Much better than the auto injector. If using the auto injector at 50mg 1x/wk it burns and gives an injection site reaction from the preservative in it. If using the prefilled syringe at 50 mg 1x/wk, it's not as bad and only stings. Again from the preservative. It works. I take it without methotrexate. F 50 7 years
25mg 2x wk
10/1/2015
 5  R A ENBREL is a god send from 1994 to starting ENBREL in 1999 I was in lots of pain 24 hrs a day . Nothing else worked . I am virtually no pain . Thank you to the people who invented ENBREL M 62 10 years
25g
9/27/2015
 1  My sister took one shot My sister took 1 shot of this on Sunday 8/30/2015 around 8:30 pm. She went to sleep at 10:30 pm that night and never woke up--she passed away in her sleep. She was only 46. Her RA was a recent diagnosis and she had tried some pills for it but her RA doctor put her on the shot. F 46 1 days
1X day
9/21/2015
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 5  JIA and ankolising spondylitis None It works wonder to me I can't barely walk and feeling depressed all the time because of constant pain. And since I started enbrel I am pain free F 38 9 months
50 mg
9/8/2015
 2  RA After the 1st dose, I thought Enbrel was my miracle but after the second dose I experienced extreme nauseas for 4 days. I called my RA doc who wanted me to discontinue next dose of methotrexate and Enbrel then take next dose of Enbrel by itself. That night I had the nausea but next morning things seemed fine. I had slight confusion through the morning and felt 'burned' by the sun when I took students outside. I ended up losing conscience and having extreme confusion (maybe a seizure) over the next 2-3 hours. Went to er, had normal MRI and CT, blood sugar and cell counts but still felt confusion, inability to make my body respond to mental commands, difficulty speaking words that I wanted to say (mentally not physically). After 2 days I was still having nausea even with drinking water and now it's been 3 days and I'm still drinking Boost (no appetite) and still some brain fog. I still feel worried and afraid of long-term effects. F 58 24 days
50 MG 1X W
8/28/2015
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 5  rheumatoid arthritis Injection site inflammation for first six months then I got better at injecting all ok now. Works well for my RA.Inflamatory markers normal last 3.5 years. F 67 4 years
50mg
8/18/2015
 1  Ra After taking enbrel for over 2years, I got sinus infections and cough that lasted 3-4 months this year. Overall I felt sickly this year. 2 months ago I broke out in blisters on my hands and scaley red spots on my foot. Dermatologist did biopsy and diagnosed psoriasis and to stop enbrel. My ra doctor agreed and is looking for alternate drug. I knew something was wrong with my health but had no idea it was enbrel doing the damage. I felt safe from side effects because of the length of time on enbrel. I was wrong. F 59 2 years
1X W
8/14/2015
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