ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Ankylosing Spondylitis Occasional dizziness, almost feel hung over, but without drinking. Don't know if it's the Enbrel, or just getting used to not being on ibuprofen all the time. Skin doesn't seem as healthy as before, zits don't heal as fast. I am doing things I couldn't do before. Driving long distances, lifting objects, strenuous yard work. I've even stopped taking drops for my recurrent iritis. The Enbrel is working great at stopping the AS. However, I don't feel physically at the top of my game, and I don't know why. M 54 3 months
50mg 1X W
8/12/2016
 4  Ankolosing spondilitis Blurred vision ,saddness, small bruise at injection sight. Usaully goes away before next injction. Other than these small things has reduces stiffness greatly has allowed me to walk around and began to enjoy simple things like putting on my own clothes and serving my own dinner.. Overall ..success M 31 8 months
7/28/2016
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 3  RA Diagnosed with RA 8 months ago. Started with Xeljanz but worked well for 3 months only. I followed a strict diet of eating only good foods for like leafy vegetable,deep sea fish and fruits. Took 3 caps turmeric daily, Kefir and accupuncture. Actually, before I started with embrel my ESR was down to 35 from 39. I Just had 2 shots of embrel 25mg so I don't see the difference yet. I refrained from Salt, sugar, red meats, preserve meats and all foods bad for RA. I did my own research, doctors are maybe busy to guide patients on this but really all these help. The joint pains and tightness in my fingers are minimal. F 62 7 days
6/19/2016
 4  RA Extreme fatigue for 1-3 days after injecting F 1 months
50 1X W
6/6/2016
 4  RA Extreme tiredness and lethargy that comes and goes. Feelings of depression when tired. Sinus infections that are manageable. I use Enbrel with Methotrexate. I didn't want to commence with either of these drugs, as I have avoided drugs all my adult life. However after reading all the literature available to me, I did commence and the pain of RA has diminished. I still suffer flare ups and have minor side effects from the drugs (others seem to suffer more so). At this stage all going ok F 47 18 months
50mg 1X W
5/22/2016
 1  RA PAIN AND DEFORMITY OF JOINTS It has helped the pain but the rash and starts immediately after injection have tried everything but always get a rash that lasts 2 to 3 weeks. Call Embrel and they are no help the nurses just read the instructions to me. Well I know how to read, I want to know why the rashes and why do they take so long to clear. The HELL with what Embrel states; if you have a skin reaction it will clear up in 3 to 7 days, in reality it clears up in 5 to 8 weeks. They could have better nurses that actually have experience in doing injections. And are able to give rational and informed communication. F 70 2 months
50 1X W
5/12/2016
 4  RA Rash at injection sites and headaches and stomach pain F 57 2 months
30mg
5/11/2016
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 1  AS At start ok however now bad site reactions. Rash and pain at site. Sore throat and ear. Extreme tiredness.Blurred vision. I had a similar reaction with humira . Biologics are very risky and backup on UK is very poor. M 64 2 months
50mg
4/30/2016
 1  Rheumatoid arthritis Was on Humira for about a year until the sinus infections became so bad I took myself off dr. suggested Enbrel . Was taking it for about four months , my last injection left my leg swollen itchy Which wasn't a big problem for me it went away in a few days . It's been probably three weeks since my last injection , I've called my dr to find another remedy . I'm short of breath coughing having night sweats and just all-around miserable . Biologics just aren't for me .. Since I've been off the injection I'm feeling very stiff and sore but I'm also dealing with chest congestion possible lung infection . At this point I'm just afraid of the Biologics . I can't deal with being deathly ill 99% of the time . F 50 3 months
4/7/2016
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 5  Ankylosing Spondylitis Slow skin healing, easy discoloration I had a positive experience with Enbrel from my first injection... No injection-site reactions or other side effects... I experienced noticeable improvement in SI, neck, and hip pain after 2 injections, with continued improvement. After several months I noticed slower wound healing, and discoloration after a cut or breakout had healed. With the reduction in pain, my stress decreased, I was able to increase exercise & stretching, sleep more, bring inflammation down, and stop using the Enbtel after a year and a half. I discontinued using it without tapering- listened to my body, and stopped when I felt I was ready. A couple things I found helpful from the beginning: to utilize breathing & relaxation techniques just before & during each injection, and to inject into a fleshy area of my upper thigh. F 47 18 months
50mg 1X W
3/22/2016
 5  Psoriatic Arthritis Very slight injection location rash which no longer happens Was very apprehensive about being told by my Rheumy that my psoriatic arthritis was quite severe and that I should take this drug. I also hated the idea of having to inject myself. However, since I started taking this drug 4 months ago, after an initial 4/6 weeks, the main side effect is that I feel great. The chronic foot and back pain is gone. The muscle pain and general fatigue is also in the past. I didn't realise how badly I was affected by my arthritis until the Enbrel took effect. Time will tell how effective this is and if I get any nasty side effects, but for now, this is truly a miracle drug for me. M 50 4 months
50mg 1X W
3/5/2016
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 5  RA I have an ongoing slight sinus infecton which gets worse if I get a cold. Which is about 2 times a year and I get on antibiotic. Recently I have been getting dizzy and was just wondering if it had something to do with the medication, that's why I am on this site. Trying to learn the long term effects from your experiences. I had severe pain in my joints for three 3 years prior to being on Enbrel. It improved the quality of my life. I have flare ups but they are not debilitating. F 53 10 years
50 MG 1x w
3/5/2016
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 3  Severe RA Diarrhea, dizziness, painful injections. Just recently started working kinda and am off the leflunomide and prednisone for the time being. Just Aleve and the enbrel. To anyone discouraged by the medicine not working I please urge you to keep going and ask your doctor about how long until you feel the effects... Only bad part is I've been shutting my brains out. I guess it beats crying in a fetal position... M 27 3 months
1 syringe
2/29/2016
 2  ankolosing spondilitis no side effects but also no relief, have just as much pain if not more. I cannot bear this anymore I am so miserable. F 60 1 months
50 mg week 1X W
2/22/2016
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 3  Rheumatoid Arthritis Severe disfiguring of my thigh. Usually after injection, there is a lump under the skin for several days. But, 3 weeks ago my injection site looked totally different. I have a fist sized deep dent on the side of my thigh. It totally makes me sick to look at. And it's very noticeable while wearing jeans, leggings, etc. I thought it would get better by now. I have no idea what to do. F 49 1 years
50 MG
2/13/2016
Email
 4  as Headaches and hair loss F 43 1 weeks
50mg
2/8/2016
Email
 5  Ra Really none. Occasional sinus infection I hardly have any joint damage F 70 16 years
25mg 2X W
2/4/2016
 1  A.S. I have a bad case of A.S. I went to ucla when this drug came out. took it for 2mo then the wounds start so I stop it. this was 8+yrs ago I still go to Wound care ever Wk and almost died 2 Times from infections. Good luck! M 48 1 days
2/3/2016
 4  Rheumatoid Arthritis The drug is brilliant at controlling arthritis and I have no pain and no flare ups whatsoever. However, I'm on the verge of losing my job because I get so many infections and illnesses which leaves me feeling really down and totally out of control because I have to call in sick a lot. I now have to decide which is worse - having arthritis pain and flare ups or being constantly ill. F 37 4 years
2/1/2016
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 2  Ra No side effects Wore off after about 6 years. But now in worse shape then before. Have had RA for almost 20 years. Enbrel better then MTX and Arava F 36 8 years
1/19/2016

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