ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Ra Really none. Occasional sinus infection I hardly have any joint damage F 70 16 years
25mg 2X W
2/4/2016
 5  psoriasis arthritis has worked wonderful.no side effects except for one time when i was hospitalized for hepatitis. F 63 15 years
50mg 1X W
11/21/2014
 5   Very slight skin dry spots I have been injecting for 15 years, it was a complete game changer for me was close to being unable to work, but have been in employment the whole duration, was one of the first to be prescribed, I’ve been asked by my rhumetologist if I would like to go back to methotrexate but the thought fills me with trepidation. M 55 15 years
50mg
10/17/2018
Email
 5  ra Started taking Enbrel when it first came out in the early 90's and it was a Godsend! Before taking Enbrel I had very little energy and my fingers were starting to get deformed. I took everything that was available. After taking Enbrel I felt great immediately, less swelling & joint pain, more energy, and I do not have any disfiguration of fingers. Over the years I have developed female yeast infections and yeast in my digestive tract and mouth. I manage these by taking non-milk based acidophilas and staying away from yeast breads and eating very little bread & pasta prodcts. I also take arava along with the Enbrel and this controls my ra. I also take calcium & vitamin D as I am now of the age to get octeoarthritis. I was diagnosed when I was 12 with jra and am now 56 years and hold down a full time job and have lots of energy. I do like the 50mg autoinjector, very convenient. I understand that Enbrel is not for everyone, but it has worked wonders for me. I understand the side effects, and I have minimal brusing/itching at injection site, I inject myself on thighs and back of arms. F 56 15 years
8/16/2009
 4  Psoriatic and Rheumatoid Arthritis After being on this drug for many years I developed a mysterious and severe staph infection in my cervical spine, threatening paralysis. Doctors couldn't figure out what was going on and did emergency surgery and biopsy. Several disc fusions and months on antibiotic fusions, doctors took me off Enbrel, thinking lowered immunity led to staph infection. Was off for two years and tried methotrexate. That was horrible and eventually went back to Enbrel. Seem to get every cold, virus, and sinus infection possible. Resistant to antibiotics. Began this drug many years ago off label before approved. Even with serious complications, being on Enbrel has allowed me to live relatively pain free and function almost normally. Didn't really control the psoriasis though. F 58 15 years
50mg 1X W
3/19/2013
 5  RA No side effects. Completely changed my life--I would be in a wheelchair by now w/o Enbrel. Was initially on MTX, plaquenil and minocycline but couldn't get above the lowest dose of MTX because of bone marrow suppression. Went on Enbrel as soon as it came out and experienced relief within days. What little pain I experienced with regular inj was nothing compared to RA pain....have no pain at all with autoject. Some side effects that people experience would occur with RA regardless of being on Enbrel--I know this from being a healthcare professional myself. You just have to weigh the pros and cons and decide if the benefit outweighs the risk. F 48 14 years
50MG 1X W
4/16/2013
 5  Psoriatic Arthritis Mild injection site reaction Amazing, immediate results after one injection; alleviated all pain and kept the progression of my disease in check for 14 years. VERY pleased with Enbrel - gave me my life back. Not sure why, may have been linked to hormone changes brought on by menopause, (?) but I began to have pain, stiffness and swelling in my finger/hand/wrist, along with pain in feet, stiffness upon waking all over, back and neck pain. Rheumatologist switched me to Humira with no change, added Arava - been on this for a month with little to no change. F 47 14 years
50 MG 1X W
10/31/2017
 5  R A ENBREL is a god send from 1994 to starting ENBREL in 1999 I was in lots of pain 24 hrs a day . Nothing else worked . I am virtually no pain . Thank you to the people who invented ENBREL M 62 10 years
25g
9/27/2015
 5  RA I have an ongoing slight sinus infecton which gets worse if I get a cold. Which is about 2 times a year and I get on antibiotic. Recently I have been getting dizzy and was just wondering if it had something to do with the medication, that's why I am on this site. Trying to learn the long term effects from your experiences. I had severe pain in my joints for three 3 years prior to being on Enbrel. It improved the quality of my life. I have flare ups but they are not debilitating. F 53 10 years
50 MG 1x w
3/5/2016
Email
 5  plaque psoriasis & psoriatic arthri Very occasional injection site reaction. F 30 10 years
50 mg
9/29/2013
Email
 5  rheumatoid and osteo arthritis For the first six weeks, had red bump at injection site. Ten years on, I still feel tired after a shot. Have frequent heartburn, and generally feel a bit low, even though nothing's wrong. Colds are more severe, and sinus problems are frequent. I tried the pre-mixed once a week injections, but the twice a week is painless, due to having a 7.4 ph, unlike the pre-mix. This is not a perfect drug. Is there such a thing? But I would probably be dead by now if not for this. I had severe RA with high sed rate and nothing (and I tried nearly everything) had more than a slight effect. I felt better after my first two shots. Much damage had already occured, but Enbrel seems to have nearly stopped the progression. If an excess of tumor necrosis factor-a is what is going on with your arthritis, this may be the best drug for you, if you have good health insurance or are independently wealthy. Added advice-take vitamin d and c for your immune system. F 65 10 years
1/13/2010
Email
 5  RA More infections such as sinus. Not much else. This is a miracle drug in my book. The opportunity to do what others do, live a normal life. I have been on Enbrel since it came out. I was one of the first patients in GA to have access to the drug back when you had to register with the manufacturer to obtain the medication. My advancement was slowed so much it is unbelievable. When diagnosed in 1992 I was given 18 months to be in a wheel chair. I'm not, never have been. I have had several surgeries over the years and never have any issues healing. I would suggest this drug to anyone willing to go on living. It has made a difference in my life beyond any comprehension. F 51 10 years
6/16/2009
 5  rheumatoid arthritis none I began taking Enbrel about 10 years ago on 3rd phase testing, double blind study. I knew the first two weeks that I had the drug and not a placibo. I went into a complete remission for about 2 1/2 years. I haven't had even one flare since I started injecting Enbrel. However, I feel that it isn't working as well as the first 2 1/2 years, but I am still very happy with this drug. I feel that it has changed the course of my RA, I have only one MCP joint that has some damage. Great Drug!! F 63 10 years
7/29/2007
Email
 5  Juvenile Rheumatoid Arthritis (JRA) I have been one of the lucky few who has been virtually side effect free. I have occassional injection site reactions (maybe 1 out of every 10). They are just itchy for a few days, and I barely notice them. Otherwise, I believe that Enbrel has caused a lupus like red rash on my face (tested negative for lupus). Not painful at all, responds to topical steroids for the self conscious. Biggest problem is that if you get any serious infection, you probably will have to get off the Enbrel until it goes away. Its in times like those that you really appreciate how much the medicine is doing for you I was on methotrexate and extremely high doses of NSAIDS before getting the opportunity to try enbrel. My doctor encouraged it, and I was fortunate enough to have an insurance willing to pay the massive costs. It is EXPENSIVE. Very EXPENSIVE. Might be less than some other options, but my insurance company is shelling out $1,500+/month. If other things have failed for you, please consider talking to your doctor about this kind of treatment. It has changed my life in so many ways and allows me to do things(walking almost pain free, jogging, even running with a little work in the gym first to strengthen up those muscles). M 24 10 years
5/22/2008
 4  RA Horrible itchy rash for 1 year, 'white matter on the brain, lost periods of time, vision abnormalities. I am going through test to determine if I have MS. Enbrel was great until it side effects hit me like a bomb. F 59 10 years
50mg 1X W
10/12/2011
 4  ra Fungal lung infection have caught every bug that comes along it helped my joints but do not like all the side effects M 65 10 years
50mg
11/5/2013
Email
 3  RA Enbrel was an amazing drug for me for many years with little to no side effects until the last year. Started to get bizarre rashes. Went to a couple of dermatologists and was put on high doses of prednisone which made me crazy and my family fear my wrath. Lol. Those of you who have had the roid rage understand. They just said it was eczema. RA doctor did not know what rash was either. Finally the rash got so bad went to another dermatologist who was (is) amazing and biopsied rash. Thank goodness she discovered I had a severe staph infection. (presently going through this. If i hadn't gone to her I could have been hospitalized. I think after long term use it may cause infections. Don't know why this just started to happen. I'm going to call Enbrel's hotline and inform them. Going to find new RA doctor and stop Enbrel. I have been a huge advocate and know how it can change your life. Sorry it is causing rashes and infections. Good Luck to everyone as I know how tough it is to have an a F 49 10 years
50 mg 1X W
8/10/2015
Email
 3  psoriatic arthritis and psoriasis malignant kidney tumor; loss of teeth due to infection M 52 10 years
50 mg 1X W
2/20/2013
 1  Psoriatic arthritis Very first day enbrel came on market my doctor called to get the injection because methotrexate wasn't working tried both pill and needle it was making me nauseated Enbrel worked good at beginning but short time after started getting infections. I was on and off for a few years until 2010 I got a serious infection that almost cost me my life all organs shut down I was on a respiratory life support with a trac. I keep getting pnomenia in and out hospital getting trac changed. I can't talk walk only dignity I have left feed myself. I can't believe a drug that's suppose to help make life easier ruined mine. But I wanted to feel good be able to go out to work pain free but now I rather suffer a little pain then of taken enbrel F 55 10 years
25 mg
12/8/2013
Email
 5  psoriatic arthritis Absolutely none. The 50 mg. injection can be slightly painful, but I learned that this can be lessened significantly by letting the syringe warm up a bit after taking it out of the fridge. I wait 15 minutes and then inject. Also, the best place to inject is around the naval. Enough fat there to absorb the needle easily without hitting any blood vessels! This is a miracle drug. I have been on Enbrel for almost ten years, and let me tell you, it gave me back my life. I am no longer in constant pain, the bone in by finger joints has regrown and my fingers do not appear as misshapen, and I no longer need to take Celebrex or any other NSAID. The scientists at Immunex who developed this drug should be given the Noble Prize. Think about it. Kids who were in wheelchairs are now playing football. An absolute miracle drug. M 52 9.5 years
2/4/2009
Email
  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

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