ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  psoratic arthritis So far no virtually no side effects. I sleep more, but since I was having trouble sleeping, this has not been a problem. I had arthritis in my hands so bad that in the mornings I had to run hot water over them to get them moving. With Enbrel the problem has disappeared. 64 3 months
8/14/2008
 5  
6/16/2009
 3  
7/20/2009
 3  Ankylosing Spondyloathritis 1 days
50mg a wl
1/8/2016
 3  Akloysing spondylitis It has taken my hair out and my nails But the only one that works.Was on the surecluck my dr lowered my dose from 50 to 25 and the drugstore sent syringes I can't do it the arthritis in my hands is so bad I can't do it so now all I want to do is cry and this stuff hurts so bad when it's injects I've heard the syringes hurt worse. Need to fix the pain aspect of this drug 62 4 months
25 now 1X W
10/3/2022
Email
 2  PsA Even more fatigue than I already had. Then I started getting rashes that seemed to thicken. I went to the dermatologist and she couldn’t really explain it but gave me some ointment for it. I also started getting headaches which I hadn’t had for 20 years. It got to the point at the end of the day were the only energy I had left I had to decide whether to brush my teeth or wash my face. Brushing teeth always comes out on top. I felt a little better like the first month and then it just drastically has gotten worse. Oh yes and the restless legs the knots in my calf muscles are the worst. I never understood what people were talking about that had restless legs. Now I know and they keep you up for hours on end at night. I took my last shot last Friday and I’ll never go on it again. 58 0 months
40mg
2/13/2019
 1  RA nausea; eventually side effects include cancer and MS. Note if you send me a message provide your e-mail address or I cannot respond the drugs will poison you; try the honey and vinegar diet which cured me and vitamins! (esp niacinamide) See for instance Dr Saul's website at doctoryourself.com or his book Fire Your Doctor. Everything is curable, 'just say no to drugs'. (Nancy Reagan) 55 30 days
50 mg 1X W
2/3/2011
Email

Patient History
 5  RA No bad side effects After reading some of the comments on here I had to respond. I'm a hospital nurse on a medical unit and have been exposed to H1N1, TB, and many other things. I have never gotton sick even with having less ability to fight infections. There are also many comments about the injections being painful. I don't feel it at all. I don't use the autoject. I allow it to reach room temp, clean an area on my belly with alcohol and Allow it to dry. Then pinch up an area and inject slowly. I have noticed it hurts some if injected to fast which may be a problem with the autojects. I wouldn't be walking if I wasn't taking this drug. F 57 4 years
50mg 1X W
11/27/2010
Email
 5  RA Very minor discomfort with the injections. Not using the Sure-click as that IS painful. I also take Methotrexate and have finally weaned myself entirely off of Predizone. My feelings are very much the same as the that of the person leaving the last comment. Just hoping Enbrel continues to work because my life without it was beyond awful. F 58 3 years
50mg 1X W
12/1/2010
Email
 5  RA & Psoriasis I have had no side effects It is a wonderful drug and changed my life, it not only cleared up my psoriasis but also my RA had improved 90% before I had to get shots of cortizone in my hand just to function F 70 4 years
30mg 1X W
11/16/2010
Email
 5  RA Enbrel has given me my life back not in so much pain as before I started the drug.How ever I have experince some weight gain as a result of taking the meds. F 38 5 weeks
50mg 1X W
10/16/2010
 5  RA Redness, lump at injection site Wonderful drug. Gave me back my life! F 52 8 weeks
50mg 1X W
8/23/2010
 5  Psoriatic Arthritis The injections are painful - and I'm no wimp. I take the 50mg Sureclik once a week. The night before my 3rd injection I developed a large hive at each of the previous 2 injection sites. They took a full 2 weeks to go away. No issues since, although I take an antihistamine daily now... just in case. Dizzy at times. No trouble thus far with infections. I had no idea how bad I felt overall until it went away. The lethargy that I had come to accept as "just the way I am" - lifted like a fog during the first week of treatment. Literally for the first time in years I feel awake, alert and full of enough energy to live my life. My arthritis is much improved, and I am excited about life again. I am, however, concerned about the potential serious side effects... but for today, I am feeling better than I have in YEARS. F 44 3 months
1/28/2010
 5  RA As far as I am concerned I have had no side effects. Oh I get bloody noses but that is when the air is dry, or I get numbness, but that is because I use the coumputer mouse too much. I get a cold once a year, but I did before Enbrel, so nothing new there. It has been the best thing and has kept my joints from degenerating and has allowed me to continue working. I am almost 61 and came down with RA during menopause, so about 13-15 years ago. Every day I can walk or work and I thank Enbrel for that. F 61 8 years
50mg 1X W
2/12/2010
Email
 5  ankylosing spodilitus Tiredness, headaches and a weird rash under by right cheek which has spread...sure it is something to do with enbrel it has given me my life back! F 31 3 months
15mg 1X W
2/20/2010
 5  rheumatoid arthritis occasional spots on trunk of body Enbrel has transformed by life. I was in severe pain, now this has been considerably reduced. F 53 4 years
50mg 1X W
3/5/2010
 5  Rheumatoid Arthritis a few minutes of itching which began about 3 hours after the injection I'm shocked. Had put off taking this drug due to fear of side effects...had opted for "alternative relief" from RA. Had some success with that but remained in great pain....so finally tried the Enbrel injection. Relief was experienced the very next day!!! (was in big flare situation day first shot was taken) Relief has remained constant. Just took 2nd injection and am very grateful for the improvement. Soooo, so far, so very good! F 58 7 days
50mg 1X W
4/12/2010
Email
 5  Rhuematoid arthritis no side effects SECRET TO PAINFREE INJECTION!!! After a terrible experience with my first (CLICK) injection given by the doctor in his office I was terrified to try this at home. The first one was excrutiatingly painful. The 2nd one given by my husband at home went without a hitch. I let the click pen warm to room temerature for 30 minutes. Took 2 Ibroprophen and 2 Xanax an hour before the injection. I iced the injection site (thigh) with a blue ice pack for a few minutes until it was numb. My husband slightly stretched the skin where he was going to inject. The medication went in within 7-10 seconds with just a very slight (barely noticeable) sting. The only glitch was we waited and waited for that 2nd click.... then realized my husband was still holding down the purple button. After 45 seconds and a confirmed purple reading of the medication indicator we assumed all the med was safely injected. I am the biggest baby in the world when it comes to needles... so this was not easy for me and I fretted and made myself sick over this impending injection. But it was a breeze....even tho the needle was in 3 times longer than it should of been. Of course you would want to check with your doctor regarding the Ibro and Xanax... but it sure helped me! I think stretching the skin helped too. ANYWAY... I felt nothing but a slight sting as the med went in. 2 weeks ago I was on mega doses of Predisone and could barely function. Today I walked the mall with no pain at all and am off F 60 2 weeks
50mg 1X W
5/19/2010
Email
 5  Rheumatoid Arthritis No side effects at all This drug completely cancelled my severe RA - it has slowly improved my already previously deformed joints as well. Fantastic and hard to believe, but true! Now I have been off it for a year and living in total misery, feeling suicidal every day. My hands are useless and I can hardly walk. I only stopped taking Enbrel because of some other patients mentioning cancer in the on-line forums like this one... Now thinking of starting this medication again, bacause I want to LIVE! F 36 4 years
50 1X W
5/30/2010
Email
 5  rheumatoid arthritis none Works better than humira, which semi worked, still had regualr achy pain from RA, skin crawling, etc. F 53 2 years
50mg 1X W
6/10/2010
  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

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