ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  RA None Worked for 5 years. At times I could go 5 weeks between shots, then take an injection when I felt stiffness coming on. Then it stopped working. M 81 5 years
50mg 1X W
5/6/2013
 5  Rheumatiod Arthritis Some injection site itching. Perhaps increased severity of sinus infections. Took 6 weeks to take effect, and when it did, it relieved 90% of symptoms. It is not a miracle drug..still get tired easily, and do not have former strength, but before Enbrel, I couldn't even turn the key to start my truck, and had difficulty in slipping a credit card in and out of a gas pump. I can now resume controlling a shopping cart with one hand, so it has worked well, even with time-outs for back and hip surgery. Previously, I had a terrible reaction to methotrexate [and it did work for 2 months from the original dose, but on trying it again, it worked not at all]. Enbrel let me get off Prednisone entirely. I hope it keeps working. Medicare part D helps a bunch, but I go through the donut hole in late February to mid March M 77 2 years
10/28/2007
 4  Rheum Arthritis None so far {5 weekly injections]. Supposed to take weekly, but I stretch to between 8 and 9 days intervals. Seems to be working...am 50-60% improved over nothing, and can open jar lids, open cans, drive. Is Expensive, but Medicare supplement program pays for out of pocket over $3,600 for this and a few other drugs. M 75 35 days
10/13/2005
 5  Mixed Connective Tissue Disease After 5 years of 100% relief, am now getting serious infections and will need to get off drug (regrettably). This is a known side effect. These infections can even be life threatening. Gave me a normal life after years of rheumatoid arthritis, severe, joint pains with no relief from other meds, except large doses of prednisone M 72 5 years
10/24/2005
 5  RA no side effects This is the Best medication for my arthritis. I have tried many others one but no one has helped me so much. M 71 7 years
1X W
5/25/2013
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 5  RA & Psoriasis I have had no side effects It is a wonderful drug and changed my life, it not only cleared up my psoriasis but also my RA had improved 90% before I had to get shots of cortizone in my hand just to function F 70 4 years
30mg 1X W
11/16/2010
Email
 5  Ra Really none. Occasional sinus infection I hardly have any joint damage F 70 16 years
25mg 2X W
2/4/2016
 1  RA PAIN AND DEFORMITY OF JOINTS It has helped the pain but the rash and starts immediately after injection have tried everything but always get a rash that lasts 2 to 3 weeks. Call Embrel and they are no help the nurses just read the instructions to me. Well I know how to read, I want to know why the rashes and why do they take so long to clear. The HELL with what Embrel states; if you have a skin reaction it will clear up in 3 to 7 days, in reality it clears up in 5 to 8 weeks. They could have better nurses that actually have experience in doing injections. And are able to give rational and informed communication. F 70 2 months
50 1X W
5/12/2016
 4  rheumatoid arthritis Serious cough and dry reaching or vomiting nearly every day. Severe stomach pain when eating or just after eating. Red, itchy rash on lower legs and spreading. Cortisone cream does not help it at all. Have had pneumonia several times a year and also prone to catching any infection going around. Enbrel worked from the very first injection. Absolutely fantastic BUT now experiencing severe side effects. Have had all necessary tests done to find out why coughing and vomiting and all have come back clear so can only blame it on the Enbrel. Not nice to be out to dinner, one cough and then vomiting. F 68 2 years
50 mg 1X W
10/28/2015
 3  Psoriasis, Sapho Syndrome Possibly edema and increased psoriatic breakouts Took 50 mg Enbrel for 6 weeks every seven days. After extremely high SED rate came within normal range, was advised to take every ten days which I've been doing for two months. I seem to be getting more psoriasis flare-ups and little red bumps all over my body more frequently. Does anyone else feel that the Enbrel makes their psoriasis worse? F 68 4 months
1/3/2009
 5  RA Have had no side effects Works very well. Couldn't believe how fast it started working. Got off of it for 3-4 weeks because of sinus infection and the difference was amazing. After I got back on it, I could tell a big improvement almost immediately. M 67 8 months
10/1/2007
 5  rheumatoid arthritis Injection site inflammation for first six months then I got better at injecting all ok now. Works well for my RA.Inflamatory markers normal last 3.5 years. F 67 4 years
50mg
8/18/2015
 4  Plaque Psoriasis Outbreak of guttate psoriasis in the last three months. Have stopped injecting Enbrel but still dealing with the same psoriais which my derm says is not an unusual side effect after using Enbrel for this length of time. Not sure which is worse, the plaque or guttate psoriasis. Enbrel worked quite well until this episode took place. Plaque psoriasis has not worsened since stopping Enbrel, only the guttate. M 67 5 years
8/20/2008
Email
 3  Rheumatoid arthritis Brain fog extreme tiredness pain rash on my leg sometimes it leaves me feeling in a box the world is going on and I'm in a box horrible feeling may not continue I see my doctor on Monday I want to see if there's another alternative I feel at this point my blood test showed everything is normal even my arthritis is normal I don't feel normal F 67 6 months
50
12/26/2015
 3  Pa Rash on face when in the sun i use the multi dose vials and they do not hurt at all, if I have to use those others methods of injection I would not use Embrel F 67 2 years
50
3/20/2015
Email
 4  AS So far I have no side effects I felt improvement from first week I had taken enbrel , now I feel almost 80% of my pain is gone M 66 7 months
50 mg 1X W
3/20/2012
Email
 3  Rheumatoid arthritis After 2 months on Enbrel I had no more pain. However, I had to stop taking it shortly after due to a perforated colon with abscess. Reading various articles seems to prove that this is not an uncommon side effect. My doctor wants me to start taking it again, but I have decided not to as I do not want to run the risk of another intestinal problem. M 66 2 months
4/28/2009
Email
 5  rheumatoid and osteo arthritis For the first six weeks, had red bump at injection site. Ten years on, I still feel tired after a shot. Have frequent heartburn, and generally feel a bit low, even though nothing's wrong. Colds are more severe, and sinus problems are frequent. I tried the pre-mixed once a week injections, but the twice a week is painless, due to having a 7.4 ph, unlike the pre-mix. This is not a perfect drug. Is there such a thing? But I would probably be dead by now if not for this. I had severe RA with high sed rate and nothing (and I tried nearly everything) had more than a slight effect. I felt better after my first two shots. Much damage had already occured, but Enbrel seems to have nearly stopped the progression. If an excess of tumor necrosis factor-a is what is going on with your arthritis, this may be the best drug for you, if you have good health insurance or are independently wealthy. Added advice-take vitamin d and c for your immune system. F 65 10 years
1/13/2010
Email
 5  RA Occasional injection site redness and pain. Intermittent hives. Maybe coincidental but 7 surgeries in the last 12 months for basal cell and squamous cell skin cancer. Intermittent dry skin. I will take all of the side effects rather than change from Enbrel. It has been a life changing drug allowing me to live a full and active life. RA had started to attack my lungs and this drug stopped it dead in its tracks. M 65 18 months
50mg 1X W
11/29/2011
 5  Severe psoriatic Arthritus Guaranteed to have a sore throat within 24 hours. Minor inconvenience. Have over 28 joints involved. Took Humira for 18 months and then it stopped working. Disease is virtually completely controlled with Enbrel. I am a useless blob without this medication. No help on my relatively minor psoriasis. Single dose of 50mg gives me horrible series side effects. M 65 1.5 years
25mg 2X W
3/6/2011
Email
  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

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